MENU
+Compare
IONS
Stock ticker: NASDAQ
AS OF
Dec 24 closing price
Price
$80.65
Change
+$0.32 (+0.40%)
Capitalization
13.06B

IONS Ionis Pharmaceuticals Forecast, Technical & Fundamental Analysis

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs... Show more

Industry: #Biotechnology
IONS
Daily Signal:
Gain/Loss:
Interact to see
Advertisement
A.I.Advisor
a Summary for IONS with price predictions
Dec 24, 2025

IONS's Stochastic Oscillator drives into overbought zone

The Stochastic Oscillator for IONS moved into overbought territory on December 24, 2025. Be on the watch for a price drop or consolidation in the future -- when this happens, think about selling the stock or exploring put options.

Price Prediction Chart

Technical Analysis (Indicators)

Bearish Trend Analysis

The 10-day RSI Indicator for IONS moved out of overbought territory on December 02, 2025. This could be a bearish sign for the stock. Traders may want to consider selling the stock or buying put options. Tickeron's A.I.dvisor looked at 26 similar instances where the indicator moved out of overbought territory. In of the 26 cases, the stock moved lower in the following days. This puts the odds of a move lower at .

The Moving Average Convergence Divergence Histogram (MACD) for IONS turned negative on December 09, 2025. This could be a sign that the stock is set to turn lower in the coming weeks. Traders may want to sell the stock or buy put options. Tickeron's A.I.dvisor looked at 52 similar instances when the indicator turned negative. In of the 52 cases the stock turned lower in the days that followed. This puts the odds of success at .

Following a 3-day decline, the stock is projected to fall further. Considering past instances where IONS declined for three days, the price rose further in of 62 cases within the following month. The odds of a continued downward trend are .

IONS broke above its upper Bollinger Band on November 24, 2025. This could be a sign that the stock is set to drop as the stock moves back below the upper band and toward the middle band. You may want to consider selling the stock or exploring put options.

Bullish Trend Analysis

The Momentum Indicator moved above the 0 level on December 23, 2025. You may want to consider a long position or call options on IONS as a result. In of 98 past instances where the momentum indicator moved above 0, the stock continued to climb. The odds of a continued upward trend are .

Following a 3-day Advance, the price is estimated to grow further. Considering data from situations where IONS advanced for three days, in of 280 cases, the price rose further within the following month. The odds of a continued upward trend are .

The Aroon Indicator entered an Uptrend today. In of 223 cases where IONS Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are .

Fundamental Analysis (Ratings)

The Tickeron Price Growth Rating for this company is (best 1 - 100 worst), indicating steady price growth. IONS’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.

The Tickeron Seasonality Score of (best 1 - 100 worst) indicates that the company is fair valued in the industry. The Tickeron Seasonality score describes the variance of predictable price changes around the same period every calendar year. These changes can be tied to a specific month, quarter, holiday or vacation period, as well as a meteorological or growing season.

The Tickeron Profit vs. Risk Rating rating for this company is (best 1 - 100 worst), indicating well-balanced risk and returns. The average Profit vs. Risk Rating rating for the industry is 94, placing this stock slightly better than average.

The Tickeron PE Growth Rating for this company is (best 1 - 100 worst), pointing to consistent earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.

The Tickeron SMR rating for this company is (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.

The Tickeron Valuation Rating of (best 1 - 100 worst) indicates that the company is significantly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (21.142) is normal, around the industry mean (26.541). P/E Ratio (0.000) is within average values for comparable stocks, (51.479). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (1.873). Dividend Yield (0.000) settles around the average of (0.049) among similar stocks. P/S Ratio (13.245) is also within normal values, averaging (311.015).

View a ticker or compare two or three
IONS
Daily Signal:
Gain/Loss:
Interact to see
Advertisement
A.I. Advisor
published Earnings

IONS is expected to report earnings to rise 63.75% to -130 cents per share on February 25

Ionis Pharmaceuticals IONS Stock Earnings Reports
Q4'25
Est.
$-1.31
Q3'25
Beat
by $0.42
Q2'25
Beat
by $0.94
Q1'25
Beat
by $0.15
Q4'24
Beat
by $0.45
The last earnings report on October 29 showed earnings per share of -80 cents, beating the estimate of -122 cents. With 480.23K shares outstanding, the current market capitalization sits at 13.06B.
A.I. Advisor
published General Information

General Information

a developer of antisense drugs

Industry Biotechnology

Profile
Fundamentals
Details
Industry
Biotechnology
Address
2855 Gazelle Court
Phone
+1 760 931-9200
Employees
927
Web
https://www.ionispharma.com
Interesting Tickers
1D
1W
1M
1Q
6M
1Y
5Y
1 Day
ETFs / NAMEPrice $Chg $Chg %
OZEM35.500.25
+0.70%
Roundhill GLP-1 & Weight Loss ETF
NOCT58.200.05
+0.08%
Innovator Growth-100 Pwr Buff ETF™ Oct
RODM37.130.02
+0.05%
Hartford Multifactor Dev Mkts (exUS) ETF
HYDR34.14-0.01
-0.03%
Global X Hydrogen ETF
MUNY103.27-0.17
-0.16%
Vanguard New York Tx-Exm Bd ETF

IONS and Stocks

Correlation & Price change

A.I.dvisor indicates that over the last year, IONS has been loosely correlated with CYTK. These tickers have moved in lockstep 63% of the time. This A.I.-generated data suggests there is some statistical probability that if IONS jumps, then CYTK could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To IONS
1D Price
Change %
IONS100%
+0.40%
CYTK - IONS
63%
Loosely correlated
+1.41%
MLYS - IONS
49%
Loosely correlated
+0.21%
MNKD - IONS
48%
Loosely correlated
N/A
ARWR - IONS
47%
Loosely correlated
+0.40%
IDYA - IONS
47%
Loosely correlated
+0.76%
More