SYRE
Price
$22.63
Change
-$0.80 (-3.41%)
Updated
Nov 13 closing price
Capitalization
1.76B
104 days until earnings call
Intraday BUY SELL Signals
ZURA
Price
$4.18
Change
-$0.45 (-9.72%)
Updated
Nov 13 closing price
Capitalization
272.43M
Intraday BUY SELL Signals
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SYRE vs ZURA

Header iconSYRE vs ZURA Comparison
Open Charts SYRE vs ZURABanner chart's image
Spyre Therapeutics
Price$22.63
Change-$0.80 (-3.41%)
Volume$514.56K
Capitalization1.76B
Zura Bio
Price$4.18
Change-$0.45 (-9.72%)
Volume$549.32K
Capitalization272.43M
SYRE vs ZURA Comparison Chart in %
SYRE
Daily Signal:
Gain/Loss:
ZURA
Daily Signal:
Gain/Loss:
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VS
SYRE vs. ZURA commentary
Nov 14, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SYRE is a Buy and ZURA is a Hold.

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COMPARISON
Comparison
Nov 14, 2025
Stock price -- (SYRE: $23.43 vs. ZURA: $4.63)
Brand notoriety: SYRE and ZURA are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: SYRE: 64% vs. ZURA: 37%
Market capitalization -- SYRE: $1.76B vs. ZURA: $272.43M
SYRE [@Biotechnology] is valued at $1.76B. ZURA’s [@Biotechnology] market capitalization is $272.43M. The market cap for tickers in the [@Biotechnology] industry ranges from $110.25B to $0. The average market capitalization across the [@Biotechnology] industry is $2.1B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SYRE’s FA Score shows that 0 FA rating(s) are green whileZURA’s FA Score has 1 green FA rating(s).

  • SYRE’s FA Score: 0 green, 5 red.
  • ZURA’s FA Score: 1 green, 4 red.
According to our system of comparison, ZURA is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SYRE’s TA Score shows that 5 TA indicator(s) are bullish while ZURA’s TA Score has 3 bullish TA indicator(s).

  • SYRE’s TA Score: 5 bullish, 5 bearish.
  • ZURA’s TA Score: 3 bullish, 4 bearish.
According to our system of comparison, both SYRE and ZURA are a good buy in the short-term.

Price Growth

SYRE (@Biotechnology) experienced а +2.54% price change this week, while ZURA (@Biotechnology) price change was +27.55% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.51%. For the same industry, the average monthly price growth was -3.12%, and the average quarterly price growth was +61.90%.

Reported Earning Dates

SYRE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+1.51% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($1.76B) has a higher market cap than ZURA($272M). ZURA has higher P/E ratio than SYRE: ZURA (7.96) vs SYRE (1.72). ZURA YTD gains are higher at: 85.200 vs. SYRE (0.644). ZURA has higher annual earnings (EBITDA): -72.34M vs. SYRE (-222.15M). SYRE has more cash in the bank: 527M vs. ZURA (154M). SYRE (0) and ZURA (0) have equivalent revenues.
SYREZURASYRE / ZURA
Capitalization1.76B272M646%
EBITDA-222.15M-72.34M307%
Gain YTD0.64485.2001%
P/E Ratio1.727.9622%
Revenue00-
Total Cash527M154M342%
Total Debt0N/A-
FUNDAMENTALS RATINGS
SYRE: Fundamental Ratings
SYRE
OUTLOOK RATING
1..100
86
VALUATION
overvalued / fair valued / undervalued
1..100
68
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
97
PRICE GROWTH RATING
1..100
40
P/E GROWTH RATING
1..100
77
SEASONALITY SCORE
1..100
85

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
SYREZURA
RSI
ODDS (%)
Bearish Trend 2 days ago
88%
Bearish Trend 2 days ago
50%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
89%
Bearish Trend 2 days ago
59%
Momentum
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
56%
MACD
ODDS (%)
Bearish Trend 2 days ago
87%
Bullish Trend 2 days ago
54%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
83%
Bullish Trend 2 days ago
50%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
51%
Advances
ODDS (%)
Bullish Trend 2 days ago
84%
Bullish Trend 2 days ago
82%
Declines
ODDS (%)
Bearish Trend 8 days ago
90%
Bearish Trend 10 days ago
83%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
43%
Aroon
ODDS (%)
Bullish Trend 2 days ago
86%
N/A
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SYRE
Daily Signal:
Gain/Loss:
ZURA
Daily Signal:
Gain/Loss:
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SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with APGE. These tickers have moved in lockstep 59% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then APGE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+0.34%
APGE - SYRE
59%
Loosely correlated
+0.24%
CGON - SYRE
58%
Loosely correlated
+1.47%
IDYA - SYRE
57%
Loosely correlated
-0.19%
RGNX - SYRE
56%
Loosely correlated
+0.43%
NRIX - SYRE
56%
Loosely correlated
-5.37%
More

ZURA and

Correlation & Price change

A.I.dvisor indicates that over the last year, ZURA has been loosely correlated with SYRE. These tickers have moved in lockstep 44% of the time. This A.I.-generated data suggests there is some statistical probability that if ZURA jumps, then SYRE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ZURA
1D Price
Change %
ZURA100%
+4.75%
SYRE - ZURA
44%
Loosely correlated
+0.34%
FATE - ZURA
43%
Loosely correlated
-7.14%
CGON - ZURA
42%
Loosely correlated
+1.47%
BDTX - ZURA
41%
Loosely correlated
+5.41%
FULC - ZURA
40%
Loosely correlated
+2.58%
More