SYRE
Price
$33.05
Change
-$0.18 (-0.54%)
Updated
Dec 24 closing price
Capitalization
2.56B
63 days until earnings call
Intraday BUY SELL Signals
XBI
Price
$126.30
Change
+$1.41 (+1.13%)
Updated
Dec 24 closing price
Net Assets
8.54B
Intraday BUY SELL Signals
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SYRE vs XBI

Header iconSYRE vs XBI Comparison
Open Charts SYRE vs XBIBanner chart's image
Spyre Therapeutics
Price$33.05
Change-$0.18 (-0.54%)
Volume$291.96K
Capitalization2.56B
State Street® SPDR® S&P® Biotech ETF
Price$126.30
Change+$1.41 (+1.13%)
Volume$3.3M
Net Assets8.54B
SYRE vs XBI Comparison Chart in %
SYRE
Daily Signal:
Gain/Loss:
XBI
Daily Signal:
Gain/Loss:
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VS
SYRE vs. XBI commentary
Dec 25, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SYRE is a Hold and XBI is a StrongBuy.

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COMPARISON
Comparison
Dec 25, 2025
Stock price -- (SYRE: $33.05)
Brand notoriety:
Market capitalization --

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SYRE’s FA Score shows that 0 FA rating(s) are green while.

  • SYRE’s FA Score: 0 green, 5 red.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SYRE’s TA Score shows that 2 TA indicator(s) are bullish.

  • SYRE’s TA Score: 2 bullish, 6 bearish.

Price Growth

SYRE (@Biotechnology) experienced а -0.03% price change this weekfor the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.88%. For the same industry, the average monthly price growth was +4.46%, and the average quarterly price growth was +55.39%.

Reported Earning Dates

SYRE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+2.88% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS RATINGS
SYRE: Fundamental Ratings
SYRE
OUTLOOK RATING
1..100
64
VALUATION
overvalued / fair valued / undervalued
1..100
70
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
97
PRICE GROWTH RATING
1..100
36
P/E GROWTH RATING
1..100
80
SEASONALITY SCORE
1..100
50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
SYREXBI
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
83%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
83%
Momentum
ODDS (%)
Bearish Trend 2 days ago
84%
Bullish Trend 2 days ago
90%
MACD
ODDS (%)
Bearish Trend 2 days ago
89%
Bearish Trend 2 days ago
90%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
87%
Bullish Trend 2 days ago
88%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
83%
Bullish Trend 2 days ago
88%
Advances
ODDS (%)
Bullish Trend 8 days ago
85%
Bullish Trend 4 days ago
89%
Declines
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 8 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
87%
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
Bullish Trend 2 days ago
84%
Bullish Trend 2 days ago
88%
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SYRE
Daily Signal:
Gain/Loss:
XBI
Daily Signal:
Gain/Loss:
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SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with BEAM. These tickers have moved in lockstep 57% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then BEAM could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
-0.54%
BEAM - SYRE
57%
Loosely correlated
+1.33%
XNCR - SYRE
57%
Loosely correlated
-0.13%
RGNX - SYRE
57%
Loosely correlated
+0.77%
CGON - SYRE
56%
Loosely correlated
+0.22%
APGE - SYRE
56%
Loosely correlated
+1.02%
More

XBI and

Correlation & Price change

A.I.dvisor indicates that over the last year, XBI has been closely correlated with IDYA. These tickers have moved in lockstep 72% of the time. This A.I.-generated data suggests there is a high statistical probability that if XBI jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To XBI
1D Price
Change %
XBI100%
+1.13%
IDYA - XBI
72%
Closely correlated
+0.76%
XNCR - XBI
70%
Closely correlated
-0.13%
BEAM - XBI
70%
Closely correlated
+1.33%
SYRE - XBI
70%
Closely correlated
-0.54%
NUVL - XBI
68%
Closely correlated
+0.89%
More