SYRE
Price
$16.95
Change
+$0.09 (+0.53%)
Updated
Aug 15 closing price
Capitalization
1.02B
80 days until earnings call
TPST
Price
$10.53
Change
+$1.05 (+11.08%)
Updated
Aug 15 closing price
Capitalization
46.75M
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SYRE vs TPST

Header iconSYRE vs TPST Comparison
Open Charts SYRE vs TPSTBanner chart's image
Spyre Therapeutics
Price$16.95
Change+$0.09 (+0.53%)
Volume$536.98K
Capitalization1.02B
Tempest Therapeutics
Price$10.53
Change+$1.05 (+11.08%)
Volume$224.55K
Capitalization46.75M
SYRE vs TPST Comparison Chart in %
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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TPST
Daily Signalchanged days ago
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SYRE vs. TPST commentary
Aug 18, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SYRE is a Hold and TPST is a Hold.

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COMPARISON
Comparison
Aug 18, 2025
Stock price -- (SYRE: $16.95 vs. TPST: $10.53)
Brand notoriety: SYRE and TPST are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: SYRE: 90% vs. TPST: 211%
Market capitalization -- SYRE: $1.02B vs. TPST: $46.75M
SYRE [@Biotechnology] is valued at $1.02B. TPST’s [@Biotechnology] market capitalization is $46.75M. The market cap for tickers in the [@Biotechnology] industry ranges from $100.71B to $0. The average market capitalization across the [@Biotechnology] industry is $1.88B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SYRE’s FA Score shows that 0 FA rating(s) are green whileTPST’s FA Score has 0 green FA rating(s).

  • SYRE’s FA Score: 0 green, 5 red.
  • TPST’s FA Score: 0 green, 5 red.
According to our system of comparison, TPST is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SYRE’s TA Score shows that 6 TA indicator(s) are bullish while TPST’s TA Score has 5 bullish TA indicator(s).

  • SYRE’s TA Score: 6 bullish, 3 bearish.
  • TPST’s TA Score: 5 bullish, 4 bearish.
According to our system of comparison, SYRE is a better buy in the short-term than TPST.

Price Growth

SYRE (@Biotechnology) experienced а +11.22% price change this week, while TPST (@Biotechnology) price change was +43.07% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +5.94%. For the same industry, the average monthly price growth was +21.39%, and the average quarterly price growth was +21.23%.

Reported Earning Dates

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+5.94% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($1.02B) has a higher market cap than TPST($46.8M). TPST YTD gains are higher at: -2.936 vs. SYRE (-27.191). TPST has higher annual earnings (EBITDA): -43.32M vs. SYRE (-214.36M). SYRE has more cash in the bank: 565M vs. TPST (21.5M). SYRE has less debt than TPST: SYRE (0) vs TPST (13.1M). SYRE (0) and TPST (0) have equivalent revenues.
SYRETPSTSYRE / TPST
Capitalization1.02B46.8M2,188%
EBITDA-214.36M-43.32M495%
Gain YTD-27.191-2.936926%
P/E Ratio1.68N/A-
Revenue00-
Total Cash565M21.5M2,628%
Total Debt013.1M-
FUNDAMENTALS RATINGS
SYRE vs TPST: Fundamental Ratings
SYRE
TPST
OUTLOOK RATING
1..100
1026
VALUATION
overvalued / fair valued / undervalued
1..100
73
Overvalued
53
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
99100
PRICE GROWTH RATING
1..100
5942
P/E GROWTH RATING
1..100
8490
SEASONALITY SCORE
1..100
1650

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TPST's Valuation (53) in the Pharmaceuticals Major industry is in the same range as SYRE (73). This means that TPST’s stock grew similarly to SYRE’s over the last 12 months.

TPST's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as SYRE (100). This means that TPST’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's SMR Rating (99) in the Pharmaceuticals Major industry is in the same range as TPST (100). This means that SYRE’s stock grew similarly to TPST’s over the last 12 months.

TPST's Price Growth Rating (42) in the Pharmaceuticals Major industry is in the same range as SYRE (59). This means that TPST’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's P/E Growth Rating (84) in the Pharmaceuticals Major industry is in the same range as TPST (90). This means that SYRE’s stock grew similarly to TPST’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
SYRETPST
RSI
ODDS (%)
N/A
Bearish Trend 3 days ago
90%
Stochastic
ODDS (%)
Bearish Trend 3 days ago
90%
Bearish Trend 3 days ago
90%
Momentum
ODDS (%)
Bullish Trend 3 days ago
85%
Bullish Trend 3 days ago
79%
MACD
ODDS (%)
Bullish Trend 3 days ago
87%
Bullish Trend 3 days ago
81%
TrendWeek
ODDS (%)
Bullish Trend 3 days ago
84%
Bullish Trend 3 days ago
80%
TrendMonth
ODDS (%)
Bullish Trend 3 days ago
83%
Bullish Trend 3 days ago
82%
Advances
ODDS (%)
Bullish Trend 5 days ago
85%
Bullish Trend 3 days ago
82%
Declines
ODDS (%)
Bearish Trend 10 days ago
90%
Bearish Trend 11 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 3 days ago
88%
Bearish Trend 3 days ago
90%
Aroon
ODDS (%)
Bullish Trend 3 days ago
90%
N/A
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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TPST
Daily Signalchanged days ago
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SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with IDYA. These tickers have moved in lockstep 61% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+0.53%
IDYA - SYRE
61%
Loosely correlated
-0.16%
CGON - SYRE
60%
Loosely correlated
-1.00%
BEAM - SYRE
59%
Loosely correlated
+1.08%
XNCR - SYRE
57%
Loosely correlated
+0.39%
CRNX - SYRE
55%
Loosely correlated
+3.47%
More

TPST and

Correlation & Price change

A.I.dvisor indicates that over the last year, TPST has been loosely correlated with PHIO. These tickers have moved in lockstep 51% of the time. This A.I.-generated data suggests there is some statistical probability that if TPST jumps, then PHIO could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To TPST
1D Price
Change %
TPST100%
+11.08%
PHIO - TPST
51%
Loosely correlated
-0.46%
ABCZF - TPST
49%
Loosely correlated
N/A
RXRX - TPST
38%
Loosely correlated
+2.30%
LXEO - TPST
38%
Loosely correlated
-1.46%
SYRE - TPST
37%
Loosely correlated
+0.53%
More