SRZN
Price
$22.20
Change
-$0.70 (-3.06%)
Updated
Dec 26 closing price
Capitalization
190.29M
Intraday BUY SELL Signals
UPB
Price
$29.48
Change
-$0.79 (-2.61%)
Updated
Dec 26 closing price
Capitalization
1.59B
81 days until earnings call
Intraday BUY SELL Signals
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SRZN vs UPB

Header iconSRZN vs UPB Comparison
Open Charts SRZN vs UPBBanner chart's image
Surrozen
Price$22.20
Change-$0.70 (-3.06%)
Volume$29.41K
Capitalization190.29M
Upstream Bio
Price$29.48
Change-$0.79 (-2.61%)
Volume$228.01K
Capitalization1.59B
SRZN vs UPB Comparison Chart in %
SRZN
Daily Signal:
Gain/Loss:
UPB
Daily Signal:
Gain/Loss:
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VS
SRZN vs. UPB commentary
Dec 28, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SRZN is a Hold and UPB is a StrongBuy.

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COMPARISON
Comparison
Dec 28, 2025
Stock price -- (SRZN: $22.20 vs. UPB: $29.48)
Brand notoriety: SRZN and UPB are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: SRZN: 30% vs. UPB: 47%
Market capitalization -- SRZN: $190.29M vs. UPB: $1.59B
SRZN [@Biotechnology] is valued at $190.29M. UPB’s [@Biotechnology] market capitalization is $1.59B. The market cap for tickers in the [@Biotechnology] industry ranges from $117.45B to $0. The average market capitalization across the [@Biotechnology] industry is $2.21B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SRZN’s FA Score shows that 1 FA rating(s) are green whileUPB’s FA Score has 0 green FA rating(s).

  • SRZN’s FA Score: 1 green, 4 red.
  • UPB’s FA Score: 0 green, 5 red.
According to our system of comparison, SRZN is a better buy in the long-term than UPB.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SRZN’s TA Score shows that 3 TA indicator(s) are bullish while UPB’s TA Score has 3 bullish TA indicator(s).

  • SRZN’s TA Score: 3 bullish, 6 bearish.
  • UPB’s TA Score: 3 bullish, 4 bearish.
According to our system of comparison, UPB is a better buy in the short-term than SRZN.

Price Growth

SRZN (@Biotechnology) experienced а +2.02% price change this week, while UPB (@Biotechnology) price change was +0.44% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.36%. For the same industry, the average monthly price growth was +0.27%, and the average quarterly price growth was +54.56%.

Reported Earning Dates

UPB is expected to report earnings on Mar 18, 2026.

Industries' Descriptions

@Biotechnology (+0.36% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
UPB($1.59B) has a higher market cap than SRZN($190M). UPB YTD gains are higher at: 79.319 vs. SRZN (54.704). SRZN has higher annual earnings (EBITDA): -37.23M vs. UPB (-140.33M). UPB has more cash in the bank: 372M vs. SRZN (81.3M). UPB has less debt than SRZN: UPB (1.42M) vs SRZN (7.08M). SRZN has higher revenues than UPB: SRZN (3.6M) vs UPB (2.8M).
SRZNUPBSRZN / UPB
Capitalization190M1.59B12%
EBITDA-37.23M-140.33M27%
Gain YTD54.70479.31969%
P/E RatioN/AN/A-
Revenue3.6M2.8M129%
Total Cash81.3M372M22%
Total Debt7.08M1.42M499%
TECHNICAL ANALYSIS
Technical Analysis
SRZNUPB
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
55%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
73%
Momentum
ODDS (%)
Bearish Trend 2 days ago
83%
Bullish Trend 2 days ago
73%
MACD
ODDS (%)
Bearish Trend 2 days ago
89%
Bearish Trend 2 days ago
90%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
82%
Bearish Trend 2 days ago
81%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
81%
Bullish Trend 2 days ago
90%
Advances
ODDS (%)
Bullish Trend 6 days ago
86%
Bullish Trend 20 days ago
89%
Declines
ODDS (%)
Bearish Trend 2 days ago
83%
N/A
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
82%
Bearish Trend 2 days ago
69%
Aroon
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
90%
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SRZN
Daily Signal:
Gain/Loss:
UPB
Daily Signal:
Gain/Loss:
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SRZN and

Correlation & Price change

A.I.dvisor tells us that SRZN and UPB have been poorly correlated (+29% of the time) for the last year. This A.I.-generated data suggests there is low statistical probability that SRZN and UPB's prices will move in lockstep.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SRZN
1D Price
Change %
SRZN100%
-3.04%
UPB - SRZN
29%
Poorly correlated
-2.61%
DSGN - SRZN
29%
Poorly correlated
-1.13%
AVBP - SRZN
28%
Poorly correlated
-1.44%
PDSB - SRZN
28%
Poorly correlated
+1.22%
ABEO - SRZN
27%
Poorly correlated
+0.74%
More

UPB and

Correlation & Price change

A.I.dvisor indicates that over the last year, UPB has been loosely correlated with IDYA. These tickers have moved in lockstep 42% of the time. This A.I.-generated data suggests there is some statistical probability that if UPB jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To UPB
1D Price
Change %
UPB100%
-2.61%
IDYA - UPB
42%
Loosely correlated
-1.35%
VYGR - UPB
41%
Loosely correlated
+0.25%
ORKA - UPB
40%
Loosely correlated
-1.31%
DSGN - UPB
39%
Loosely correlated
-1.13%
SYRE - UPB
39%
Loosely correlated
-0.33%
More