SRPT
Price
$22.50
Change
-$0.84 (-3.60%)
Updated
Oct 17, 04:59 PM (EDT)
Capitalization
2.36B
11 days until earnings call
SYRE
Price
$22.48
Change
+$0.24 (+1.08%)
Updated
Oct 17, 04:59 PM (EDT)
Capitalization
1.74B
19 days until earnings call
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SRPT vs SYRE

Header iconSRPT vs SYRE Comparison
Open Charts SRPT vs SYREBanner chart's image
Sarepta Therapeutics
Price$22.50
Change-$0.84 (-3.60%)
Volume$111.71K
Capitalization2.36B
Spyre Therapeutics
Price$22.48
Change+$0.24 (+1.08%)
Volume$46.04K
Capitalization1.74B
SRPT vs SYRE Comparison Chart in %
SRPT
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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SRPT vs. SYRE commentary
Oct 18, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SRPT is a Hold and SYRE is a Hold.

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COMPARISON
Comparison
Oct 18, 2025
Stock price -- (SRPT: $23.34 vs. SYRE: $22.24)
Brand notoriety: SRPT: Notable vs. SYRE: Not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: SRPT: 84% vs. SYRE: 294%
Market capitalization -- SRPT: $2.36B vs. SYRE: $1.74B
SRPT [@Biotechnology] is valued at $2.36B. SYRE’s [@Biotechnology] market capitalization is $1.74B. The market cap for tickers in the [@Biotechnology] industry ranges from $106.87B to $0. The average market capitalization across the [@Biotechnology] industry is $2.06B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SRPT’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • SRPT’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, both SRPT and SYRE are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SRPT’s TA Score shows that 6 TA indicator(s) are bullish while SYRE’s TA Score has 5 bullish TA indicator(s).

  • SRPT’s TA Score: 6 bullish, 4 bearish.
  • SYRE’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, SRPT is a better buy in the short-term than SYRE.

Price Growth

SRPT (@Biotechnology) experienced а +0.91% price change this week, while SYRE (@Biotechnology) price change was +5.05% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.56%. For the same industry, the average monthly price growth was +16.02%, and the average quarterly price growth was +79.42%.

Reported Earning Dates

SRPT is expected to report earnings on Oct 29, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+1.56% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SRPT($2.36B) has a higher market cap than SYRE($1.74B). SRPT has higher P/E ratio than SYRE: SRPT (27.21) vs SYRE (1.72). SYRE YTD gains are higher at: -4.467 vs. SRPT (-80.804). SRPT has higher annual earnings (EBITDA): 36.1M vs. SYRE (-222.15M). SRPT has more cash in the bank: 800M vs. SYRE (527M). SYRE has less debt than SRPT: SYRE (0) vs SRPT (1.35B). SRPT has higher revenues than SYRE: SRPT (2.48B) vs SYRE (0).
SRPTSYRESRPT / SYRE
Capitalization2.36B1.74B135%
EBITDA36.1M-222.15M-16%
Gain YTD-80.804-4.4671,809%
P/E Ratio27.211.721,586%
Revenue2.48B0-
Total Cash800M527M152%
Total Debt1.35B0-
FUNDAMENTALS RATINGS
SRPT vs SYRE: Fundamental Ratings
SRPT
SYRE
OUTLOOK RATING
1..100
1226
VALUATION
overvalued / fair valued / undervalued
1..100
72
Overvalued
67
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
100100
PRICE GROWTH RATING
1..100
9493
P/E GROWTH RATING
1..100
10080
SEASONALITY SCORE
1..100
875

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SYRE's Valuation (67) in the Pharmaceuticals Major industry is in the same range as SRPT (72) in the Biotechnology industry. This means that SYRE’s stock grew similarly to SRPT’s over the last 12 months.

SYRE's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as SRPT (100) in the Biotechnology industry. This means that SYRE’s stock grew similarly to SRPT’s over the last 12 months.

SYRE's SMR Rating (100) in the Pharmaceuticals Major industry is in the same range as SRPT (100) in the Biotechnology industry. This means that SYRE’s stock grew similarly to SRPT’s over the last 12 months.

SYRE's Price Growth Rating (93) in the Pharmaceuticals Major industry is in the same range as SRPT (94) in the Biotechnology industry. This means that SYRE’s stock grew similarly to SRPT’s over the last 12 months.

SYRE's P/E Growth Rating (80) in the Pharmaceuticals Major industry is in the same range as SRPT (100) in the Biotechnology industry. This means that SYRE’s stock grew similarly to SRPT’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
SRPTSYRE
RSI
ODDS (%)
Bearish Trend 2 days ago
79%
Bearish Trend 2 days ago
90%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
78%
Bearish Trend 2 days ago
90%
Momentum
ODDS (%)
Bullish Trend 2 days ago
64%
Bullish Trend 2 days ago
82%
MACD
ODDS (%)
Bullish Trend 2 days ago
80%
Bullish Trend 2 days ago
89%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
74%
Bullish Trend 2 days ago
82%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
71%
Bullish Trend 2 days ago
82%
Advances
ODDS (%)
Bullish Trend 2 days ago
75%
Bullish Trend 2 days ago
83%
Declines
ODDS (%)
Bearish Trend 4 days ago
78%
Bearish Trend 5 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
Bullish Trend 2 days ago
76%
Bearish Trend 2 days ago
90%
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SRPT
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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SRPT and

Correlation & Price change

A.I.dvisor indicates that over the last year, SRPT has been loosely correlated with ALZN. These tickers have moved in lockstep 49% of the time. This A.I.-generated data suggests there is some statistical probability that if SRPT jumps, then ALZN could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SRPT
1D Price
Change %
SRPT100%
+5.14%
ALZN - SRPT
49%
Loosely correlated
+1.72%
AXON - SRPT
43%
Loosely correlated
+1.11%
ARWR - SRPT
42%
Loosely correlated
+2.04%
BHVN - SRPT
41%
Loosely correlated
-5.07%
SYRE - SRPT
41%
Loosely correlated
+0.23%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with CGON. These tickers have moved in lockstep 59% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then CGON could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+0.23%
CGON - SYRE
59%
Loosely correlated
-2.79%
APGE - SYRE
58%
Loosely correlated
-4.39%
IDYA - SYRE
56%
Loosely correlated
-2.43%
NRIX - SYRE
55%
Loosely correlated
-3.09%
RGNX - SYRE
55%
Loosely correlated
+0.33%
More