SPRB
Price
$7.75
Change
-$0.00 (-0.00%)
Updated
Sep 26 closing price
Capitalization
4.36M
50 days until earnings call
VYNE
Price
$0.33
Change
+$0.01 (+3.12%)
Updated
Sep 26 closing price
Capitalization
8.45M
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SPRB vs VYNE

Header iconSPRB vs VYNE Comparison
Open Charts SPRB vs VYNEBanner chart's image
Spruce Biosciences
Price$7.75
Change-$0.00 (-0.00%)
Volume$824
Capitalization4.36M
VYNE Therapeutics
Price$0.33
Change+$0.01 (+3.12%)
Volume$1.46M
Capitalization8.45M
SPRB vs VYNE Comparison Chart in %
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SPRB
Daily Signalchanged days ago
Gain/Loss if bought
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VYNE
Daily Signalchanged days ago
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SPRB vs. VYNE commentary
Sep 29, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SPRB is a Buy and VYNE is a Buy.

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COMPARISON
Comparison
Sep 29, 2025
Stock price -- (SPRB: $7.75 vs. VYNE: $0.33)
Brand notoriety: SPRB and VYNE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: SPRB: 10% vs. VYNE: 52%
Market capitalization -- SPRB: $4.36M vs. VYNE: $8.45M
SPRB [@Biotechnology] is valued at $4.36M. VYNE’s [@Biotechnology] market capitalization is $8.45M. The market cap for tickers in the [@Biotechnology] industry ranges from $98.9B to $0. The average market capitalization across the [@Biotechnology] industry is $1.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SPRB’s FA Score shows that 1 FA rating(s) are green whileVYNE’s FA Score has 2 green FA rating(s).

  • SPRB’s FA Score: 1 green, 4 red.
  • VYNE’s FA Score: 2 green, 3 red.
According to our system of comparison, VYNE is a better buy in the long-term than SPRB.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SPRB’s TA Score shows that 1 TA indicator(s) are bullish while VYNE’s TA Score has 4 bullish TA indicator(s).

  • SPRB’s TA Score: 1 bullish, 8 bearish.
  • VYNE’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, VYNE is a better buy in the short-term than SPRB.

Price Growth

SPRB (@Biotechnology) experienced а -7.46% price change this week, while VYNE (@Biotechnology) price change was +9.07% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.00%. For the same industry, the average monthly price growth was +9.18%, and the average quarterly price growth was +54.60%.

Reported Earning Dates

SPRB is expected to report earnings on Nov 17, 2025.

Industries' Descriptions

@Biotechnology (+4.00% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
VYNE($8.45M) has a higher market cap than SPRB($4.36M). SPRB YTD gains are higher at: 1745.238 vs. VYNE (-90.096).
SPRBVYNESPRB / VYNE
Capitalization4.36M8.45M52%
EBITDAN/A-42.58M-
Gain YTD1745.238-90.096-1,937%
P/E RatioN/A0.71-
RevenueN/A476K-
Total CashN/A39.6M-
Total DebtN/A25K-
FUNDAMENTALS RATINGS
VYNE: Fundamental Ratings
VYNE
OUTLOOK RATING
1..100
74
VALUATION
overvalued / fair valued / undervalued
1..100
17
Undervalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
98
PRICE GROWTH RATING
1..100
65
P/E GROWTH RATING
1..100
1
SEASONALITY SCORE
1..100
41

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
SPRBVYNE
RSI
ODDS (%)
Bearish Trend 3 days ago
90%
Bullish Trend 3 days ago
84%
Stochastic
ODDS (%)
Bullish Trend 3 days ago
80%
Bearish Trend 3 days ago
88%
Momentum
ODDS (%)
Bearish Trend 3 days ago
85%
Bullish Trend 3 days ago
83%
MACD
ODDS (%)
Bearish Trend 3 days ago
89%
Bullish Trend 7 days ago
77%
TrendWeek
ODDS (%)
Bearish Trend 3 days ago
88%
Bullish Trend 3 days ago
79%
TrendMonth
ODDS (%)
Bullish Trend 3 days ago
83%
Bullish Trend 3 days ago
77%
Advances
ODDS (%)
N/A
Bullish Trend 6 days ago
80%
Declines
ODDS (%)
Bearish Trend 4 days ago
87%
Bearish Trend 4 days ago
88%
BollingerBands
ODDS (%)
Bearish Trend 3 days ago
85%
Bearish Trend 3 days ago
90%
Aroon
ODDS (%)
Bearish Trend 3 days ago
86%
Bearish Trend 3 days ago
87%
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SPRB
Daily Signalchanged days ago
Gain/Loss if bought
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VYNE
Daily Signalchanged days ago
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SPRB and

Correlation & Price change

A.I.dvisor indicates that over the last year, SPRB has been closely correlated with JBIO. These tickers have moved in lockstep 85% of the time. This A.I.-generated data suggests there is a high statistical probability that if SPRB jumps, then JBIO could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SPRB
1D Price
Change %
SPRB100%
N/A
JBIO - SPRB
85%
Closely correlated
+5.21%
IMRX - SPRB
52%
Loosely correlated
+1.00%
ENTBF - SPRB
38%
Loosely correlated
-9.76%
IMCR - SPRB
38%
Loosely correlated
-0.18%
IPSC - SPRB
36%
Loosely correlated
+4.39%
More

VYNE and

Correlation & Price change

A.I.dvisor indicates that over the last year, VYNE has been loosely correlated with NEVPF. These tickers have moved in lockstep 52% of the time. This A.I.-generated data suggests there is some statistical probability that if VYNE jumps, then NEVPF could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To VYNE
1D Price
Change %
VYNE100%
+5.00%
NEVPF - VYNE
52%
Loosely correlated
N/A
SYRE - VYNE
36%
Loosely correlated
+4.04%
ABVX - VYNE
34%
Loosely correlated
+1.02%
SPRB - VYNE
34%
Loosely correlated
N/A
EYPT - VYNE
33%
Loosely correlated
+5.38%
More