SPHRY
Price
$2.60
Change
+$0.20 (+8.33%)
Updated
Dec 8 closing price
Capitalization
101.87M
81 days until earnings call
Intraday BUY SELL Signals
ZBIO
Price
$40.21
Change
+$1.11 (+2.84%)
Updated
Dec 11 closing price
Capitalization
2.16B
75 days until earnings call
Intraday BUY SELL Signals
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SPHRY vs ZBIO

Header iconSPHRY vs ZBIO Comparison
Open Charts SPHRY vs ZBIOBanner chart's image
Starpharma Holdings
Price$2.60
Change+$0.20 (+8.33%)
Volume$3.5K
Capitalization101.87M
Zenas Biopharma
Price$40.21
Change+$1.11 (+2.84%)
Volume$209.73K
Capitalization2.16B
SPHRY vs ZBIO Comparison Chart in %
SPHRY
Daily Signal:
Gain/Loss:
ZBIO
Daily Signal:
Gain/Loss:
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SPHRY vs. ZBIO commentary
Dec 13, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is SPHRY is a Hold and ZBIO is a Hold.

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COMPARISON
Comparison
Dec 13, 2025
Stock price -- (SPHRY: $2.60 vs. ZBIO: $40.21)
Brand notoriety: SPHRY and ZBIO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: SPHRY: 224% vs. ZBIO: 45%
Market capitalization -- SPHRY: $101.87M vs. ZBIO: $2.16B
SPHRY [@Biotechnology] is valued at $101.87M. ZBIO’s [@Biotechnology] market capitalization is $2.16B. The market cap for tickers in the [@Biotechnology] industry ranges from $113.14B to $0. The average market capitalization across the [@Biotechnology] industry is $2.21B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

SPHRY’s FA Score shows that 0 FA rating(s) are green whileZBIO’s FA Score has 1 green FA rating(s).

  • SPHRY’s FA Score: 0 green, 5 red.
  • ZBIO’s FA Score: 1 green, 4 red.
According to our system of comparison, ZBIO is a better buy in the long-term than SPHRY.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SPHRY’s TA Score shows that 2 TA indicator(s) are bullish while ZBIO’s TA Score has 2 bullish TA indicator(s).

  • SPHRY’s TA Score: 2 bullish, 5 bearish.
  • ZBIO’s TA Score: 2 bullish, 6 bearish.
According to our system of comparison, SPHRY is a better buy in the short-term than ZBIO.

Price Growth

SPHRY (@Biotechnology) experienced а +8.33% price change this week, while ZBIO (@Biotechnology) price change was +5.51% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.68%. For the same industry, the average monthly price growth was +4.10%, and the average quarterly price growth was +64.61%.

Reported Earning Dates

SPHRY is expected to report earnings on Mar 03, 2026.

ZBIO is expected to report earnings on Feb 25, 2026.

Industries' Descriptions

@Biotechnology (+0.68% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
ZBIO($2.16B) has a higher market cap than SPHRY($102M). ZBIO YTD gains are higher at: 390.965 vs. SPHRY (304.166). SPHRY has higher annual earnings (EBITDA): -13.7M vs. ZBIO (-189M). ZBIO has higher revenues than SPHRY: ZBIO (15M) vs SPHRY (2.98M).
SPHRYZBIOSPHRY / ZBIO
Capitalization102M2.16B5%
EBITDA-13.7M-189M7%
Gain YTD304.166390.96578%
P/E RatioN/A2.94-
Revenue2.98M15M20%
Total CashN/A273M-
Total DebtN/A1.01M-
FUNDAMENTALS RATINGS
SPHRY vs ZBIO: Fundamental Ratings
SPHRY
ZBIO
OUTLOOK RATING
1..100
3077
VALUATION
overvalued / fair valued / undervalued
1..100
49
Fair valued
60
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
96100
PRICE GROWTH RATING
1..100
3434
P/E GROWTH RATING
1..100
10034
SEASONALITY SCORE
1..100
85n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SPHRY's Valuation (49) in the null industry is in the same range as ZBIO (60). This means that SPHRY’s stock grew similarly to ZBIO’s over the last 12 months.

SPHRY's Profit vs Risk Rating (100) in the null industry is in the same range as ZBIO (100). This means that SPHRY’s stock grew similarly to ZBIO’s over the last 12 months.

SPHRY's SMR Rating (96) in the null industry is in the same range as ZBIO (100). This means that SPHRY’s stock grew similarly to ZBIO’s over the last 12 months.

SPHRY's Price Growth Rating (34) in the null industry is in the same range as ZBIO (34). This means that SPHRY’s stock grew similarly to ZBIO’s over the last 12 months.

ZBIO's P/E Growth Rating (34) in the null industry is significantly better than the same rating for SPHRY (100). This means that ZBIO’s stock grew significantly faster than SPHRY’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
SPHRYZBIO
RSI
ODDS (%)
Bearish Trend 3 days ago
86%
Bearish Trend 3 days ago
63%
Stochastic
ODDS (%)
Bearish Trend 3 days ago
90%
Bearish Trend 3 days ago
69%
Momentum
ODDS (%)
Bearish Trend 3 days ago
80%
Bearish Trend 3 days ago
70%
MACD
ODDS (%)
Bearish Trend 3 days ago
85%
Bearish Trend 3 days ago
89%
TrendWeek
ODDS (%)
Bullish Trend 3 days ago
63%
Bullish Trend 3 days ago
90%
TrendMonth
ODDS (%)
Bullish Trend 3 days ago
60%
Bullish Trend 3 days ago
90%
Advances
ODDS (%)
Bullish Trend about 1 month ago
68%
Bullish Trend 8 days ago
90%
Declines
ODDS (%)
Bearish Trend 26 days ago
78%
Bearish Trend 4 days ago
79%
BollingerBands
ODDS (%)
Bullish Trend 3 days ago
72%
Bearish Trend 3 days ago
80%
Aroon
ODDS (%)
Bullish Trend 3 days ago
58%
Bullish Trend 3 days ago
90%
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SPHRY
Daily Signal:
Gain/Loss:
ZBIO
Daily Signal:
Gain/Loss:
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SPHRY and

Correlation & Price change

A.I.dvisor tells us that SPHRY and VACBF have been poorly correlated (+29% of the time) for the last year. This A.I.-generated data suggests there is low statistical probability that SPHRY and VACBF's prices will move in lockstep.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SPHRY
1D Price
Change %
SPHRY100%
N/A
VACBF - SPHRY
29%
Poorly correlated
N/A
SPHRF - SPHRY
25%
Poorly correlated
+15.60%
ASPHF - SPHRY
22%
Poorly correlated
N/A
INM - SPHRY
21%
Poorly correlated
+5.30%
DRUG - SPHRY
21%
Poorly correlated
+5.47%
More

ZBIO and

Correlation & Price change

A.I.dvisor indicates that over the last year, ZBIO has been loosely correlated with IDYA. These tickers have moved in lockstep 48% of the time. This A.I.-generated data suggests there is some statistical probability that if ZBIO jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ZBIO
1D Price
Change %
ZBIO100%
+2.84%
IDYA - ZBIO
48%
Loosely correlated
-0.24%
RGNX - ZBIO
47%
Loosely correlated
-1.61%
SYRE - ZBIO
46%
Loosely correlated
-0.87%
IMNM - ZBIO
46%
Loosely correlated
-3.99%
KURA - ZBIO
46%
Loosely correlated
-2.61%
More