RYTM
Price
$95.89
Change
-$2.03 (-2.07%)
Updated
Nov 13 closing price
Capitalization
6.4B
110 days until earnings call
Intraday BUY SELL Signals
XENE
Price
$40.04
Change
+$0.36 (+0.91%)
Updated
Nov 13 closing price
Capitalization
3.09B
104 days until earnings call
Intraday BUY SELL Signals
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RYTM vs XENE

Header iconRYTM vs XENE Comparison
Open Charts RYTM vs XENEBanner chart's image
Rhythm Pharmaceuticals
Price$95.89
Change-$2.03 (-2.07%)
Volume$862K
Capitalization6.4B
Xenon Pharmaceuticals
Price$40.04
Change+$0.36 (+0.91%)
Volume$967.26K
Capitalization3.09B
RYTM vs XENE Comparison Chart in %
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RYTM vs. XENE commentary
Nov 14, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is RYTM is a Hold and XENE is a Buy.

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COMPARISON
Comparison
Nov 14, 2025
Stock price -- (RYTM: $97.92 vs. XENE: $39.68)
Brand notoriety: RYTM and XENE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: RYTM: 106% vs. XENE: 84%
Market capitalization -- RYTM: $6.4B vs. XENE: $3.09B
RYTM [@Biotechnology] is valued at $6.4B. XENE’s [@Biotechnology] market capitalization is $3.09B. The market cap for tickers in the [@Biotechnology] industry ranges from $110.25B to $0. The average market capitalization across the [@Biotechnology] industry is $2.1B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

RYTM’s FA Score shows that 1 FA rating(s) are green whileXENE’s FA Score has 1 green FA rating(s).

  • RYTM’s FA Score: 1 green, 4 red.
  • XENE’s FA Score: 1 green, 4 red.
According to our system of comparison, XENE is a better buy in the long-term than RYTM.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

RYTM’s TA Score shows that 4 TA indicator(s) are bullish while XENE’s TA Score has 5 bullish TA indicator(s).

  • RYTM’s TA Score: 4 bullish, 5 bearish.
  • XENE’s TA Score: 5 bullish, 4 bearish.
According to our system of comparison, XENE is a better buy in the short-term than RYTM.

Price Growth

RYTM (@Biotechnology) experienced а -1.56% price change this week, while XENE (@Biotechnology) price change was +2.64% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.51%. For the same industry, the average monthly price growth was -3.12%, and the average quarterly price growth was +61.90%.

Reported Earning Dates

RYTM is expected to report earnings on Mar 04, 2026.

XENE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+1.51% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
RYTM($6.4B) has a higher market cap than XENE($3.09B). RYTM YTD gains are higher at: 74.920 vs. XENE (1.224). RYTM has higher annual earnings (EBITDA): -159.11M vs. XENE (-315.5M). XENE has more cash in the bank: 488M vs. RYTM (291M). RYTM has less debt than XENE: RYTM (4.19M) vs XENE (8.72M). RYTM has higher revenues than XENE: RYTM (156M) vs XENE (7.5M).
RYTMXENERYTM / XENE
Capitalization6.4B3.09B207%
EBITDA-159.11M-315.5M50%
Gain YTD74.9201.2246,118%
P/E RatioN/AN/A-
Revenue156M7.5M2,080%
Total Cash291M488M60%
Total Debt4.19M8.72M48%
FUNDAMENTALS RATINGS
RYTM vs XENE: Fundamental Ratings
RYTM
XENE
OUTLOOK RATING
1..100
7558
VALUATION
overvalued / fair valued / undervalued
1..100
79
Overvalued
73
Overvalued
PROFIT vs RISK RATING
1..100
2236
SMR RATING
1..100
10096
PRICE GROWTH RATING
1..100
4249
P/E GROWTH RATING
1..100
1005
SEASONALITY SCORE
1..100
n/a75

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

XENE's Valuation (73) in the Biotechnology industry is in the same range as RYTM (79). This means that XENE’s stock grew similarly to RYTM’s over the last 12 months.

RYTM's Profit vs Risk Rating (22) in the Biotechnology industry is in the same range as XENE (36). This means that RYTM’s stock grew similarly to XENE’s over the last 12 months.

XENE's SMR Rating (96) in the Biotechnology industry is in the same range as RYTM (100). This means that XENE’s stock grew similarly to RYTM’s over the last 12 months.

RYTM's Price Growth Rating (42) in the Biotechnology industry is in the same range as XENE (49). This means that RYTM’s stock grew similarly to XENE’s over the last 12 months.

XENE's P/E Growth Rating (5) in the Biotechnology industry is significantly better than the same rating for RYTM (100). This means that XENE’s stock grew significantly faster than RYTM’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
RYTMXENE
RSI
ODDS (%)
Bearish Trend 2 days ago
77%
Bearish Trend 2 days ago
63%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
89%
Bullish Trend 2 days ago
83%
Momentum
ODDS (%)
Bearish Trend 2 days ago
73%
Bearish Trend 2 days ago
75%
MACD
ODDS (%)
Bearish Trend 2 days ago
81%
Bearish Trend 2 days ago
62%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
77%
Bullish Trend 2 days ago
75%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
77%
Bearish Trend 2 days ago
73%
Advances
ODDS (%)
Bullish Trend 17 days ago
81%
Bullish Trend 3 days ago
72%
Declines
ODDS (%)
Bearish Trend 8 days ago
75%
Bearish Trend 7 days ago
70%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
80%
Bullish Trend 2 days ago
81%
Aroon
ODDS (%)
Bullish Trend 2 days ago
79%
Bullish Trend 2 days ago
80%
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RYTM
Daily Signal:
Gain/Loss:
XENE
Daily Signal:
Gain/Loss:
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RYTM and

Correlation & Price change

A.I.dvisor indicates that over the last year, RYTM has been loosely correlated with OCUL. These tickers have moved in lockstep 40% of the time. This A.I.-generated data suggests there is some statistical probability that if RYTM jumps, then OCUL could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To RYTM
1D Price
Change %
RYTM100%
-1.94%
OCUL - RYTM
40%
Loosely correlated
+2.41%
WVE - RYTM
40%
Loosely correlated
-4.20%
XENE - RYTM
40%
Loosely correlated
-0.60%
IDYA - RYTM
39%
Loosely correlated
-0.19%
TARS - RYTM
39%
Loosely correlated
-1.10%
More

XENE and

Correlation & Price change

A.I.dvisor indicates that over the last year, XENE has been loosely correlated with NUVL. These tickers have moved in lockstep 61% of the time. This A.I.-generated data suggests there is some statistical probability that if XENE jumps, then NUVL could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To XENE
1D Price
Change %
XENE100%
-0.60%
NUVL - XENE
61%
Loosely correlated
+0.91%
IDYA - XENE
57%
Loosely correlated
-0.19%
NRIX - XENE
54%
Loosely correlated
-5.37%
DNLI - XENE
51%
Loosely correlated
-0.34%
CRNX - XENE
51%
Loosely correlated
-0.28%
More