PTGX
Price
$88.78
Change
-$0.06 (-0.07%)
Updated
Dec 26 closing price
Capitalization
5.55B
80 days until earnings call
Intraday BUY SELL Signals
TRVI
Price
$12.85
Change
-$0.12 (-0.93%)
Updated
Dec 26 closing price
Capitalization
1.65B
88 days until earnings call
Intraday BUY SELL Signals
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PTGX vs TRVI

Header iconPTGX vs TRVI Comparison
Open Charts PTGX vs TRVIBanner chart's image
Protagonist Therapeutics
Price$88.78
Change-$0.06 (-0.07%)
Volume$390.11K
Capitalization5.55B
Trevi Therapeutics
Price$12.85
Change-$0.12 (-0.93%)
Volume$1.2M
Capitalization1.65B
PTGX vs TRVI Comparison Chart in %
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PTGX vs. TRVI commentary
Dec 28, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is PTGX is a Buy and TRVI is a Buy.

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COMPARISON
Comparison
Dec 28, 2025
Stock price -- (PTGX: $88.78 vs. TRVI: $12.85)
Brand notoriety: PTGX and TRVI are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: PTGX: 41% vs. TRVI: 62%
Market capitalization -- PTGX: $5.55B vs. TRVI: $1.65B
PTGX [@Biotechnology] is valued at $5.55B. TRVI’s [@Biotechnology] market capitalization is $1.65B. The market cap for tickers in the [@Biotechnology] industry ranges from $117.45B to $0. The average market capitalization across the [@Biotechnology] industry is $2.21B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

PTGX’s FA Score shows that 2 FA rating(s) are green whileTRVI’s FA Score has 1 green FA rating(s).

  • PTGX’s FA Score: 2 green, 3 red.
  • TRVI’s FA Score: 1 green, 4 red.
According to our system of comparison, both PTGX and TRVI are a good buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

PTGX’s TA Score shows that 3 TA indicator(s) are bullish while TRVI’s TA Score has 3 bullish TA indicator(s).

  • PTGX’s TA Score: 3 bullish, 5 bearish.
  • TRVI’s TA Score: 3 bullish, 5 bearish.
According to our system of comparison, both PTGX and TRVI are a bad buy in the short-term.

Price Growth

PTGX (@Biotechnology) experienced а +3.17% price change this week, while TRVI (@Biotechnology) price change was -1.23% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.36%. For the same industry, the average monthly price growth was +0.27%, and the average quarterly price growth was +54.56%.

Reported Earning Dates

PTGX is expected to report earnings on Mar 18, 2026.

TRVI is expected to report earnings on Mar 25, 2026.

Industries' Descriptions

@Biotechnology (+0.36% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PTGX($5.55B) has a higher market cap than TRVI($1.65B). TRVI YTD gains are higher at: 211.893 vs. PTGX (130.000). PTGX has higher annual earnings (EBITDA): 21.7M vs. TRVI (-45.74M). PTGX has more cash in the bank: 576M vs. TRVI (195M). TRVI has less debt than PTGX: TRVI (823K) vs PTGX (10.7M). PTGX has higher revenues than TRVI: PTGX (209M) vs TRVI (0).
PTGXTRVIPTGX / TRVI
Capitalization5.55B1.65B337%
EBITDA21.7M-45.74M-47%
Gain YTD130.000211.89361%
P/E Ratio134.52N/A-
Revenue209M0-
Total Cash576M195M295%
Total Debt10.7M823K1,300%
FUNDAMENTALS RATINGS
PTGX vs TRVI: Fundamental Ratings
PTGX
TRVI
OUTLOOK RATING
1..100
7781
VALUATION
overvalued / fair valued / undervalued
1..100
91
Overvalued
46
Fair valued
PROFIT vs RISK RATING
1..100
3210
SMR RATING
1..100
6797
PRICE GROWTH RATING
1..100
3835
P/E GROWTH RATING
1..100
2100
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TRVI's Valuation (46) in the Pharmaceuticals Major industry is somewhat better than the same rating for PTGX (91) in the Biotechnology industry. This means that TRVI’s stock grew somewhat faster than PTGX’s over the last 12 months.

TRVI's Profit vs Risk Rating (10) in the Pharmaceuticals Major industry is in the same range as PTGX (32) in the Biotechnology industry. This means that TRVI’s stock grew similarly to PTGX’s over the last 12 months.

PTGX's SMR Rating (67) in the Biotechnology industry is in the same range as TRVI (97) in the Pharmaceuticals Major industry. This means that PTGX’s stock grew similarly to TRVI’s over the last 12 months.

TRVI's Price Growth Rating (35) in the Pharmaceuticals Major industry is in the same range as PTGX (38) in the Biotechnology industry. This means that TRVI’s stock grew similarly to PTGX’s over the last 12 months.

PTGX's P/E Growth Rating (2) in the Biotechnology industry is significantly better than the same rating for TRVI (100) in the Pharmaceuticals Major industry. This means that PTGX’s stock grew significantly faster than TRVI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
PTGXTRVI
RSI
ODDS (%)
Bearish Trend 2 days ago
60%
Bearish Trend 2 days ago
82%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
76%
Bullish Trend 2 days ago
82%
Momentum
ODDS (%)
Bearish Trend 2 days ago
66%
Bearish Trend 2 days ago
88%
MACD
ODDS (%)
Bearish Trend 2 days ago
73%
Bearish Trend 2 days ago
85%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
80%
Bullish Trend 2 days ago
85%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
84%
Advances
ODDS (%)
Bullish Trend 4 days ago
78%
Bullish Trend 4 days ago
83%
Declines
ODDS (%)
Bearish Trend 10 days ago
74%
Bearish Trend 11 days ago
88%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
61%
Bearish Trend 2 days ago
80%
Aroon
ODDS (%)
Bullish Trend 2 days ago
81%
Bullish Trend 2 days ago
88%
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PTGX
Daily Signal:
Gain/Loss:
TRVI
Daily Signal:
Gain/Loss:
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PTGX and

Correlation & Price change

A.I.dvisor indicates that over the last year, PTGX has been loosely correlated with BIESF. These tickers have moved in lockstep 61% of the time. This A.I.-generated data suggests there is some statistical probability that if PTGX jumps, then BIESF could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PTGX
1D Price
Change %
PTGX100%
-0.07%
BIESF - PTGX
61%
Loosely correlated
N/A
TRVI - PTGX
43%
Loosely correlated
-0.93%
DNLI - PTGX
41%
Loosely correlated
-0.71%
ORMP - PTGX
37%
Loosely correlated
-6.35%
MLYS - PTGX
37%
Loosely correlated
-0.77%
More

TRVI and

Correlation & Price change

A.I.dvisor indicates that over the last year, TRVI has been loosely correlated with BIESF. These tickers have moved in lockstep 48% of the time. This A.I.-generated data suggests there is some statistical probability that if TRVI jumps, then BIESF could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To TRVI
1D Price
Change %
TRVI100%
-0.93%
BIESF - TRVI
48%
Loosely correlated
N/A
PTGX - TRVI
43%
Loosely correlated
-0.07%
QURE - TRVI
30%
Poorly correlated
-1.51%
NGNE - TRVI
30%
Poorly correlated
-0.30%
XENE - TRVI
29%
Poorly correlated
-0.38%
More