PTGX
Price
$76.94
Change
-$2.23 (-2.82%)
Updated
Oct 14 closing price
Capitalization
4.79B
21 days until earnings call
Intraday Buy/Sell Signals
TRVI
Price
$10.19
Change
+$0.48 (+4.94%)
Updated
Oct 14 closing price
Capitalization
1.24B
21 days until earnings call
Intraday Buy/Sell Signals
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PTGX vs TRVI

Header iconPTGX vs TRVI Comparison
Open Charts PTGX vs TRVIBanner chart's image
Protagonist Therapeutics
Price$76.94
Change-$2.23 (-2.82%)
Volume$1.89M
Capitalization4.79B
Trevi Therapeutics
Price$10.19
Change+$0.48 (+4.94%)
Volume$2.57M
Capitalization1.24B
PTGX vs TRVI Comparison Chart in %
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PTGX vs. TRVI commentary
Oct 16, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is PTGX is a Hold and TRVI is a Hold.

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COMPARISON
Comparison
Oct 16, 2025
Stock price -- (PTGX: $76.94 vs. TRVI: $10.19)
Brand notoriety: PTGX and TRVI are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: PTGX: 156% vs. TRVI: 108%
Market capitalization -- PTGX: $4.79B vs. TRVI: $1.24B
PTGX [@Biotechnology] is valued at $4.79B. TRVI’s [@Biotechnology] market capitalization is $1.24B. The market cap for tickers in the [@Biotechnology] industry ranges from $105.69B to $0. The average market capitalization across the [@Biotechnology] industry is $2.07B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

PTGX’s FA Score shows that 1 FA rating(s) are green whileTRVI’s FA Score has 1 green FA rating(s).

  • PTGX’s FA Score: 1 green, 4 red.
  • TRVI’s FA Score: 1 green, 4 red.
According to our system of comparison, PTGX is a better buy in the long-term than TRVI.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

PTGX’s TA Score shows that 2 TA indicator(s) are bullish while TRVI’s TA Score has 5 bullish TA indicator(s).

  • PTGX’s TA Score: 2 bullish, 6 bearish.
  • TRVI’s TA Score: 5 bullish, 4 bearish.
According to our system of comparison, TRVI is a better buy in the short-term than PTGX.

Price Growth

PTGX (@Biotechnology) experienced а +17.52% price change this week, while TRVI (@Biotechnology) price change was +6.70% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.76%. For the same industry, the average monthly price growth was +13.99%, and the average quarterly price growth was +268.92%.

Reported Earning Dates

PTGX is expected to report earnings on Nov 05, 2025.

TRVI is expected to report earnings on Nov 05, 2025.

Industries' Descriptions

@Biotechnology (+0.76% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PTGX($4.79B) has a higher market cap than TRVI($1.24B). TRVI YTD gains are higher at: 147.330 vs. PTGX (99.326). PTGX has higher annual earnings (EBITDA): 26.8M vs. TRVI (-47.19M). PTGX has more cash in the bank: 570M vs. TRVI (204M). TRVI has less debt than PTGX: TRVI (891K) vs PTGX (11.3M). PTGX has higher revenues than TRVI: PTGX (209M) vs TRVI (0).
PTGXTRVIPTGX / TRVI
Capitalization4.79B1.24B386%
EBITDA26.8M-47.19M-57%
Gain YTD99.326147.33067%
P/E Ratio105.40N/A-
Revenue209M0-
Total Cash570M204M279%
Total Debt11.3M891K1,268%
FUNDAMENTALS RATINGS
PTGX vs TRVI: Fundamental Ratings
PTGX
TRVI
OUTLOOK RATING
1..100
8122
VALUATION
overvalued / fair valued / undervalued
1..100
87
Overvalued
39
Fair valued
PROFIT vs RISK RATING
1..100
4427
SMR RATING
1..100
6397
PRICE GROWTH RATING
1..100
4136
P/E GROWTH RATING
1..100
3100
SEASONALITY SCORE
1..100
4785

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TRVI's Valuation (39) in the Pharmaceuticals Major industry is somewhat better than the same rating for PTGX (87) in the Biotechnology industry. This means that TRVI’s stock grew somewhat faster than PTGX’s over the last 12 months.

TRVI's Profit vs Risk Rating (27) in the Pharmaceuticals Major industry is in the same range as PTGX (44) in the Biotechnology industry. This means that TRVI’s stock grew similarly to PTGX’s over the last 12 months.

PTGX's SMR Rating (63) in the Biotechnology industry is somewhat better than the same rating for TRVI (97) in the Pharmaceuticals Major industry. This means that PTGX’s stock grew somewhat faster than TRVI’s over the last 12 months.

TRVI's Price Growth Rating (36) in the Pharmaceuticals Major industry is in the same range as PTGX (41) in the Biotechnology industry. This means that TRVI’s stock grew similarly to PTGX’s over the last 12 months.

PTGX's P/E Growth Rating (3) in the Biotechnology industry is significantly better than the same rating for TRVI (100) in the Pharmaceuticals Major industry. This means that PTGX’s stock grew significantly faster than TRVI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
PTGXTRVI
RSI
ODDS (%)
Bearish Trend 8 days ago
67%
Bearish Trend 8 days ago
90%
Stochastic
ODDS (%)
Bearish Trend 8 days ago
67%
Bearish Trend 8 days ago
90%
Momentum
ODDS (%)
Bearish Trend 8 days ago
73%
Bullish Trend 8 days ago
81%
MACD
ODDS (%)
Bearish Trend 8 days ago
71%
Bullish Trend 8 days ago
80%
TrendWeek
ODDS (%)
Bullish Trend 8 days ago
80%
Bullish Trend 8 days ago
84%
TrendMonth
ODDS (%)
Bullish Trend 8 days ago
82%
Bullish Trend 8 days ago
83%
Advances
ODDS (%)
Bullish Trend 22 days ago
78%
Bullish Trend 10 days ago
82%
Declines
ODDS (%)
Bearish Trend 10 days ago
77%
Bearish Trend about 1 month ago
90%
BollingerBands
ODDS (%)
Bearish Trend 8 days ago
60%
Bearish Trend 8 days ago
90%
Aroon
ODDS (%)
Bullish Trend 8 days ago
81%
Bullish Trend 8 days ago
90%
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PTGX
Daily Signalchanged days ago
Gain/Loss if bought
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TRVI
Daily Signalchanged days ago
Gain/Loss if bought
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PTGX and

Correlation & Price change

A.I.dvisor indicates that over the last year, PTGX has been closely correlated with BIESF. These tickers have moved in lockstep 66% of the time. This A.I.-generated data suggests there is a high statistical probability that if PTGX jumps, then BIESF could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PTGX
1D Price
Change %
PTGX100%
-2.82%
BIESF - PTGX
66%
Closely correlated
N/A
TRVI - PTGX
41%
Loosely correlated
+4.94%
MLYS - PTGX
38%
Loosely correlated
-0.58%
FULC - PTGX
38%
Loosely correlated
-0.69%
PLRX - PTGX
35%
Loosely correlated
+1.34%
More

TRVI and

Correlation & Price change

A.I.dvisor indicates that over the last year, TRVI has been loosely correlated with BIESF. These tickers have moved in lockstep 43% of the time. This A.I.-generated data suggests there is some statistical probability that if TRVI jumps, then BIESF could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To TRVI
1D Price
Change %
TRVI100%
+4.94%
BIESF - TRVI
43%
Loosely correlated
N/A
PTGX - TRVI
40%
Loosely correlated
-2.82%
GOSS - TRVI
29%
Poorly correlated
-2.46%
XENE - TRVI
28%
Poorly correlated
+1.45%
FATE - TRVI
28%
Poorly correlated
+7.91%
More