PTCT
Price
$49.84
Change
+$0.29 (+0.59%)
Updated
Jun 27 closing price
Capitalization
3.95B
31 days until earnings call
SYRE
Price
$15.22
Change
-$0.80 (-4.99%)
Updated
Jun 27 closing price
Capitalization
918.58M
31 days until earnings call
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PTCT vs SYRE

Header iconPTCT vs SYRE Comparison
Open Charts PTCT vs SYREBanner chart's image
PTC Therapeutics
Price$49.84
Change+$0.29 (+0.59%)
Volume$1.39M
Capitalization3.95B
Spyre Therapeutics
Price$15.22
Change-$0.80 (-4.99%)
Volume$2.21M
Capitalization918.58M
PTCT vs SYRE Comparison Chart in %
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PTCT
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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PTCT vs. SYRE commentary
Jun 30, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is PTCT is a Buy and SYRE is a Buy.

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COMPARISON
Comparison
Jun 30, 2025
Stock price -- (PTCT: $49.84 vs. SYRE: $15.22)
Brand notoriety: PTCT and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: PTCT: 108% vs. SYRE: 393%
Market capitalization -- PTCT: $3.95B vs. SYRE: $918.58M
PTCT [@Biotechnology] is valued at $3.95B. SYRE’s [@Biotechnology] market capitalization is $918.58M. The market cap for tickers in the [@Biotechnology] industry ranges from $304.6B to $0. The average market capitalization across the [@Biotechnology] industry is $2.32B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

PTCT’s FA Score shows that 1 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • PTCT’s FA Score: 1 green, 4 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, PTCT is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

PTCT’s TA Score shows that 6 TA indicator(s) are bullish while SYRE’s TA Score has 5 bullish TA indicator(s).

  • PTCT’s TA Score: 6 bullish, 4 bearish.
  • SYRE’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, PTCT is a better buy in the short-term than SYRE.

Price Growth

PTCT (@Biotechnology) experienced а -0.72% price change this week, while SYRE (@Biotechnology) price change was +1.40% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.13%. For the same industry, the average monthly price growth was +31.22%, and the average quarterly price growth was +12.91%.

Reported Earning Dates

PTCT is expected to report earnings on Jul 31, 2025.

SYRE is expected to report earnings on Jul 31, 2025.

Industries' Descriptions

@Biotechnology (+4.13% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PTCT($3.95B) has a higher market cap than SYRE($919M). PTCT has higher P/E ratio than SYRE: PTCT (7.66) vs SYRE (1.68). PTCT YTD gains are higher at: 10.412 vs. SYRE (-34.622). PTCT has higher annual earnings (EBITDA): 839M vs. SYRE (-214.36M). PTCT has more cash in the bank: 2.03B vs. SYRE (565M). SYRE has less debt than PTCT: SYRE (0) vs PTCT (390M). PTCT has higher revenues than SYRE: PTCT (1.77B) vs SYRE (0).
PTCTSYREPTCT / SYRE
Capitalization3.95B919M430%
EBITDA839M-214.36M-391%
Gain YTD10.412-34.622-30%
P/E Ratio7.661.68454%
Revenue1.77B0-
Total Cash2.03B565M359%
Total Debt390M0-
FUNDAMENTALS RATINGS
PTCT vs SYRE: Fundamental Ratings
PTCT
SYRE
OUTLOOK RATING
1..100
5050
VALUATION
overvalued / fair valued / undervalued
1..100
99
Overvalued
75
Overvalued
PROFIT vs RISK RATING
1..100
98100
SMR RATING
1..100
10098
PRICE GROWTH RATING
1..100
4864
P/E GROWTH RATING
1..100
1884
SEASONALITY SCORE
1..100
85n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SYRE's Valuation (75) in the Pharmaceuticals Major industry is in the same range as PTCT (99) in the Biotechnology industry. This means that SYRE’s stock grew similarly to PTCT’s over the last 12 months.

PTCT's Profit vs Risk Rating (98) in the Biotechnology industry is in the same range as SYRE (100) in the Pharmaceuticals Major industry. This means that PTCT’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's SMR Rating (98) in the Pharmaceuticals Major industry is in the same range as PTCT (100) in the Biotechnology industry. This means that SYRE’s stock grew similarly to PTCT’s over the last 12 months.

PTCT's Price Growth Rating (48) in the Biotechnology industry is in the same range as SYRE (64) in the Pharmaceuticals Major industry. This means that PTCT’s stock grew similarly to SYRE’s over the last 12 months.

PTCT's P/E Growth Rating (18) in the Biotechnology industry is significantly better than the same rating for SYRE (84) in the Pharmaceuticals Major industry. This means that PTCT’s stock grew significantly faster than SYRE’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
PTCTSYRE
RSI
ODDS (%)
Bearish Trend 4 days ago
90%
Bearish Trend 4 days ago
88%
Stochastic
ODDS (%)
Bullish Trend 4 days ago
80%
Bullish Trend 4 days ago
89%
Momentum
ODDS (%)
Bearish Trend 4 days ago
89%
Bearish Trend 4 days ago
89%
MACD
ODDS (%)
Bearish Trend 4 days ago
78%
Bearish Trend 4 days ago
86%
TrendWeek
ODDS (%)
Bearish Trend 4 days ago
78%
Bullish Trend 4 days ago
84%
TrendMonth
ODDS (%)
Bullish Trend 4 days ago
77%
Bullish Trend 4 days ago
84%
Advances
ODDS (%)
Bullish Trend 4 days ago
74%
Bullish Trend 21 days ago
84%
Declines
ODDS (%)
Bearish Trend 11 days ago
81%
Bearish Trend 11 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 4 days ago
82%
Bearish Trend 4 days ago
90%
Aroon
ODDS (%)
Bullish Trend 4 days ago
81%
Bullish Trend 4 days ago
90%
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PTCT
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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PTCT and

Correlation & Price change

A.I.dvisor indicates that over the last year, PTCT has been loosely correlated with RXRX. These tickers have moved in lockstep 44% of the time. This A.I.-generated data suggests there is some statistical probability that if PTCT jumps, then RXRX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PTCT
1D Price
Change %
PTCT100%
+0.59%
RXRX - PTCT
44%
Loosely correlated
-6.85%
SYRE - PTCT
44%
Loosely correlated
-4.99%
XNCR - PTCT
42%
Loosely correlated
-3.10%
BEAM - PTCT
42%
Loosely correlated
-1.98%
IDYA - PTCT
42%
Loosely correlated
-4.13%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with CGON. These tickers have moved in lockstep 57% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then CGON could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
-4.99%
CGON - SYRE
57%
Loosely correlated
-0.46%
BEAM - SYRE
55%
Loosely correlated
-1.98%
IMNM - SYRE
54%
Loosely correlated
-0.23%
APGE - SYRE
53%
Loosely correlated
N/A
XNCR - SYRE
53%
Loosely correlated
-3.10%
More