PGEN
Price
$3.85
Change
+$0.15 (+4.04%)
Updated
Sep 24, 04:59 PM (EDT)
Capitalization
1.31B
49 days until earnings call
SYRE
Price
$17.01
Change
+$0.99 (+6.18%)
Updated
Sep 24, 04:59 PM (EDT)
Capitalization
967.62M
43 days until earnings call
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PGEN vs SYRE

Header iconPGEN vs SYRE Comparison
Open Charts PGEN vs SYREBanner chart's image
Precigen
Price$3.85
Change+$0.15 (+4.04%)
Volume$104.21K
Capitalization1.31B
Spyre Therapeutics
Price$17.01
Change+$0.99 (+6.18%)
Volume$34.27K
Capitalization967.62M
PGEN vs SYRE Comparison Chart in %
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PGEN
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
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PGEN vs. SYRE commentary
Sep 25, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is PGEN is a Hold and SYRE is a StrongBuy.

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COMPARISON
Comparison
Sep 25, 2025
Stock price -- (PGEN: $3.71 vs. SYRE: $16.02)
Brand notoriety: PGEN and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: PGEN: 58% vs. SYRE: 176%
Market capitalization -- PGEN: $1.31B vs. SYRE: $967.62M
PGEN [@Biotechnology] is valued at $1.31B. SYRE’s [@Biotechnology] market capitalization is $967.62M. The market cap for tickers in the [@Biotechnology] industry ranges from $97.36B to $0. The average market capitalization across the [@Biotechnology] industry is $1.91B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

PGEN’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • PGEN’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, PGEN is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

PGEN’s TA Score shows that 4 TA indicator(s) are bullish while SYRE’s TA Score has 4 bullish TA indicator(s).

  • PGEN’s TA Score: 4 bullish, 4 bearish.
  • SYRE’s TA Score: 4 bullish, 6 bearish.
According to our system of comparison, PGEN is a better buy in the short-term than SYRE.

Price Growth

PGEN (@Biotechnology) experienced а -4.63% price change this week, while SYRE (@Biotechnology) price change was +8.10% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.90%. For the same industry, the average monthly price growth was +10.70%, and the average quarterly price growth was +54.52%.

Reported Earning Dates

PGEN is expected to report earnings on Nov 12, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+4.90% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PGEN($1.31B) has a higher market cap than SYRE($968M). PGEN YTD gains are higher at: 231.250 vs. SYRE (-31.186). PGEN has higher annual earnings (EBITDA): -121.98M vs. SYRE (-222.15M). SYRE has more cash in the bank: 527M vs. PGEN (59.8M). SYRE has less debt than PGEN: SYRE (0) vs PGEN (5.15M). PGEN has higher revenues than SYRE: PGEN (4.34M) vs SYRE (0).
PGENSYREPGEN / SYRE
Capitalization1.31B968M135%
EBITDA-121.98M-222.15M55%
Gain YTD231.250-31.186-742%
P/E RatioN/A1.68-
Revenue4.34M0-
Total Cash59.8M527M11%
Total Debt5.15M0-
FUNDAMENTALS RATINGS
PGEN vs SYRE: Fundamental Ratings
PGEN
SYRE
OUTLOOK RATING
1..100
5679
VALUATION
overvalued / fair valued / undervalued
1..100
71
Overvalued
72
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10098
PRICE GROWTH RATING
1..100
3585
P/E GROWTH RATING
1..100
10081
SEASONALITY SCORE
1..100
8521

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

PGEN's Valuation (71) in the null industry is in the same range as SYRE (72) in the Pharmaceuticals Major industry. This means that PGEN’s stock grew similarly to SYRE’s over the last 12 months.

PGEN's Profit vs Risk Rating (100) in the null industry is in the same range as SYRE (100) in the Pharmaceuticals Major industry. This means that PGEN’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's SMR Rating (98) in the Pharmaceuticals Major industry is in the same range as PGEN (100) in the null industry. This means that SYRE’s stock grew similarly to PGEN’s over the last 12 months.

PGEN's Price Growth Rating (35) in the null industry is somewhat better than the same rating for SYRE (85) in the Pharmaceuticals Major industry. This means that PGEN’s stock grew somewhat faster than SYRE’s over the last 12 months.

SYRE's P/E Growth Rating (81) in the Pharmaceuticals Major industry is in the same range as PGEN (100) in the null industry. This means that SYRE’s stock grew similarly to PGEN’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
PGENSYRE
RSI
ODDS (%)
Bearish Trend 2 days ago
86%
Bullish Trend 2 days ago
86%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
88%
Bullish Trend 2 days ago
82%
Momentum
ODDS (%)
Bearish Trend 2 days ago
89%
Bearish Trend 2 days ago
89%
MACD
ODDS (%)
Bearish Trend 2 days ago
86%
Bearish Trend 2 days ago
90%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
86%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
86%
Bearish Trend 2 days ago
89%
Advances
ODDS (%)
Bullish Trend 29 days ago
84%
Bullish Trend 2 days ago
84%
Declines
ODDS (%)
Bearish Trend 6 days ago
84%
Bearish Trend 9 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
90%
Bullish Trend 2 days ago
78%
Aroon
ODDS (%)
Bullish Trend 2 days ago
87%
Bearish Trend 2 days ago
89%
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PGEN
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
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PGEN and

Correlation & Price change

A.I.dvisor indicates that over the last year, PGEN has been loosely correlated with ZNTL. These tickers have moved in lockstep 40% of the time. This A.I.-generated data suggests there is some statistical probability that if PGEN jumps, then ZNTL could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PGEN
1D Price
Change %
PGEN100%
-3.64%
ZNTL - PGEN
40%
Loosely correlated
-1.32%
XENE - PGEN
39%
Loosely correlated
-0.11%
MRNA - PGEN
38%
Loosely correlated
-2.90%
KPTI - PGEN
38%
Loosely correlated
+27.86%
SYRE - PGEN
38%
Loosely correlated
+4.77%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with CGON. These tickers have moved in lockstep 59% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then CGON could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+4.77%
CGON - SYRE
59%
Loosely correlated
-0.92%
IDYA - SYRE
59%
Loosely correlated
+0.04%
XNCR - SYRE
57%
Loosely correlated
-0.67%
CRNX - SYRE
56%
Loosely correlated
+6.35%
BEAM - SYRE
55%
Loosely correlated
-2.79%
More