NGNE
Price
$17.56
Change
-$14.00 (-44.36%)
Updated
Feb 3 closing price
Capitalization
270.45M
Intraday BUY SELL Signals
SYRE
Price
$31.97
Change
-$1.32 (-3.97%)
Updated
Feb 4, 12:24 PM (EDT)
Capitalization
2.59B
22 days until earnings call
Intraday BUY SELL Signals
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NGNE vs SYRE

Header iconNGNE vs SYRE Comparison
Open Charts NGNE vs SYREBanner chart's image
Neurogene
Price$17.56
Change-$14.00 (-44.36%)
Volume$114.44K
Capitalization270.45M
Spyre Therapeutics
Price$31.97
Change-$1.32 (-3.97%)
Volume$100
Capitalization2.59B
NGNE vs SYRE Comparison Chart in %
NGNE
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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NGNE vs. SYRE commentary
Feb 04, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is NGNE is a Hold and SYRE is a Hold.

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COMPARISON
Comparison
Feb 04, 2026
Stock price -- (NGNE: $17.56 vs. SYRE: $33.29)
Brand notoriety: NGNE and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: NGNE: 68% vs. SYRE: 62%
Market capitalization -- NGNE: $270.45M vs. SYRE: $2.59B
NGNE [@Biotechnology] is valued at $270.45M. SYRE’s [@Biotechnology] market capitalization is $2.59B. The market cap for tickers in the [@Biotechnology] industry ranges from $118.13B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

NGNE’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • NGNE’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, SYRE is a better buy in the long-term than NGNE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

NGNE’s TA Score shows that 4 TA indicator(s) are bullish while SYRE’s TA Score has 2 bullish TA indicator(s).

  • NGNE’s TA Score: 4 bullish, 4 bearish.
  • SYRE’s TA Score: 2 bullish, 4 bearish.
According to our system of comparison, NGNE is a better buy in the short-term than SYRE.

Price Growth

NGNE (@Biotechnology) experienced а -11.63% price change this week, while SYRE (@Biotechnology) price change was -0.21% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -4.22%. For the same industry, the average monthly price growth was +3.03%, and the average quarterly price growth was +35.17%.

Reported Earning Dates

SYRE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (-4.22% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($2.59B) has a higher market cap than NGNE($270M). SYRE YTD gains are higher at: 1.618 vs. NGNE (-14.757). NGNE has higher annual earnings (EBITDA): -82.02M vs. SYRE (-223.64M). SYRE has more cash in the bank: 486M vs. NGNE (265M). SYRE has less debt than NGNE: SYRE (0) vs NGNE (11.3M). NGNE (0) and SYRE (0) have equivalent revenues.
NGNESYRENGNE / SYRE
Capitalization270M2.59B10%
EBITDA-82.02M-223.64M37%
Gain YTD-14.7571.618-912%
P/E RatioN/A1.72-
Revenue00-
Total Cash265M486M55%
Total Debt11.3M0-
FUNDAMENTALS RATINGS
NGNE vs SYRE: Fundamental Ratings
NGNE
SYRE
OUTLOOK RATING
1..100
5411
VALUATION
overvalued / fair valued / undervalued
1..100
58
Fair valued
70
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9797
PRICE GROWTH RATING
1..100
6438
P/E GROWTH RATING
1..100
10078
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

NGNE's Valuation (58) in the null industry is in the same range as SYRE (70) in the Pharmaceuticals Major industry. This means that NGNE’s stock grew similarly to SYRE’s over the last 12 months.

NGNE's Profit vs Risk Rating (100) in the null industry is in the same range as SYRE (100) in the Pharmaceuticals Major industry. This means that NGNE’s stock grew similarly to SYRE’s over the last 12 months.

NGNE's SMR Rating (97) in the null industry is in the same range as SYRE (97) in the Pharmaceuticals Major industry. This means that NGNE’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's Price Growth Rating (38) in the Pharmaceuticals Major industry is in the same range as NGNE (64) in the null industry. This means that SYRE’s stock grew similarly to NGNE’s over the last 12 months.

SYRE's P/E Growth Rating (78) in the Pharmaceuticals Major industry is in the same range as NGNE (100) in the null industry. This means that SYRE’s stock grew similarly to NGNE’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
NGNESYRE
RSI
ODDS (%)
N/A
N/A
Stochastic
ODDS (%)
Bullish Trend 2 days ago
86%
Bearish Trend 2 days ago
89%
Momentum
ODDS (%)
Bullish Trend 2 days ago
86%
Bearish Trend 2 days ago
88%
MACD
ODDS (%)
Bullish Trend 2 days ago
77%
Bearish Trend 2 days ago
89%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
87%
Bearish Trend 2 days ago
87%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
85%
Bullish Trend 2 days ago
83%
Advances
ODDS (%)
Bullish Trend 9 days ago
83%
Bullish Trend 2 days ago
85%
Declines
ODDS (%)
Bearish Trend 6 days ago
87%
N/A
BollingerBands
ODDS (%)
Bearish Trend 3 days ago
90%
Bullish Trend 2 days ago
82%
Aroon
ODDS (%)
Bearish Trend 2 days ago
89%
Bearish Trend 2 days ago
90%
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NGNE
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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NGNE and

Correlation & Price change

A.I.dvisor indicates that over the last year, NGNE has been loosely correlated with BRNS. These tickers have moved in lockstep 51% of the time. This A.I.-generated data suggests there is some statistical probability that if NGNE jumps, then BRNS could also see price increases.

1D
1W
1M
1Q
6M
1Y
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Ticker /
NAME
Correlation
To NGNE
1D Price
Change %
NGNE100%
-4.20%
BRNS - NGNE
51%
Loosely correlated
+2.76%
TSHA - NGNE
49%
Loosely correlated
+1.29%
RNAZ - NGNE
48%
Loosely correlated
-3.44%
CABA - NGNE
44%
Loosely correlated
+3.60%
SYRE - NGNE
44%
Loosely correlated
+1.65%
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