MGTX
Price
$8.26
Change
-$0.40 (-4.62%)
Updated
Nov 13 closing price
Capitalization
666.91M
118 days until earnings call
Intraday BUY SELL Signals
SPRO
Price
$2.44
Change
-$0.22 (-8.27%)
Updated
Nov 13 closing price
Capitalization
137.31M
132 days until earnings call
Intraday BUY SELL Signals
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MGTX vs SPRO

Header iconMGTX vs SPRO Comparison
Open Charts MGTX vs SPROBanner chart's image
MeiraGTx Holdings
Price$8.26
Change-$0.40 (-4.62%)
Volume$1.56M
Capitalization666.91M
Spero Therapeutics
Price$2.44
Change-$0.22 (-8.27%)
Volume$881.76K
Capitalization137.31M
MGTX vs SPRO Comparison Chart in %
MGTX
Daily Signal:
Gain/Loss:
SPRO
Daily Signal:
Gain/Loss:
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VS
MGTX vs. SPRO commentary
Nov 14, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is MGTX is a Hold and SPRO is a Hold.

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COMPARISON
Comparison
Nov 14, 2025
Stock price -- (MGTX: $8.66 vs. SPRO: $2.66)
Brand notoriety: MGTX and SPRO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: MGTX: 123% vs. SPRO: 105%
Market capitalization -- MGTX: $666.91M vs. SPRO: $137.31M
MGTX [@Biotechnology] is valued at $666.91M. SPRO’s [@Biotechnology] market capitalization is $137.31M. The market cap for tickers in the [@Biotechnology] industry ranges from $110.25B to $0. The average market capitalization across the [@Biotechnology] industry is $2.1B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

MGTX’s FA Score shows that 0 FA rating(s) are green whileSPRO’s FA Score has 1 green FA rating(s).

  • MGTX’s FA Score: 0 green, 5 red.
  • SPRO’s FA Score: 1 green, 4 red.
According to our system of comparison, SPRO is a better buy in the long-term than MGTX.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

MGTX’s TA Score shows that 4 TA indicator(s) are bullish while SPRO’s TA Score has 4 bullish TA indicator(s).

  • MGTX’s TA Score: 4 bullish, 4 bearish.
  • SPRO’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, both MGTX and SPRO are a good buy in the short-term.

Price Growth

MGTX (@Biotechnology) experienced а +0.93% price change this week, while SPRO (@Biotechnology) price change was +9.47% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.51%. For the same industry, the average monthly price growth was -3.12%, and the average quarterly price growth was +61.90%.

Reported Earning Dates

MGTX is expected to report earnings on Mar 12, 2026.

SPRO is expected to report earnings on Mar 26, 2026.

Industries' Descriptions

@Biotechnology (+1.51% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
MGTX($667M) has a higher market cap than SPRO($137M). SPRO YTD gains are higher at: 158.252 vs. MGTX (42.200). SPRO has higher annual earnings (EBITDA): -56.36M vs. MGTX (-132.21M). MGTX (32.2M) and SPRO (31.2M) have equal amount of cash in the bank . SPRO has less debt than MGTX: SPRO (3.62M) vs MGTX (80.5M). MGTX has higher revenues than SPRO: MGTX (37.9M) vs SPRO (34.1M).
MGTXSPROMGTX / SPRO
Capitalization667M137M487%
EBITDA-132.21M-56.36M235%
Gain YTD42.200158.25227%
P/E RatioN/A10.75-
Revenue37.9M34.1M111%
Total Cash32.2M31.2M103%
Total Debt80.5M3.62M2,227%
FUNDAMENTALS RATINGS
MGTX vs SPRO: Fundamental Ratings
MGTX
SPRO
OUTLOOK RATING
1..100
2127
VALUATION
overvalued / fair valued / undervalued
1..100
95
Overvalued
60
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10098
PRICE GROWTH RATING
1..100
4035
P/E GROWTH RATING
1..100
1005
SEASONALITY SCORE
1..100
3050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SPRO's Valuation (60) in the Pharmaceuticals Major industry is somewhat better than the same rating for MGTX (95) in the Biotechnology industry. This means that SPRO’s stock grew somewhat faster than MGTX’s over the last 12 months.

SPRO's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as MGTX (100) in the Biotechnology industry. This means that SPRO’s stock grew similarly to MGTX’s over the last 12 months.

SPRO's SMR Rating (98) in the Pharmaceuticals Major industry is in the same range as MGTX (100) in the Biotechnology industry. This means that SPRO’s stock grew similarly to MGTX’s over the last 12 months.

SPRO's Price Growth Rating (35) in the Pharmaceuticals Major industry is in the same range as MGTX (40) in the Biotechnology industry. This means that SPRO’s stock grew similarly to MGTX’s over the last 12 months.

SPRO's P/E Growth Rating (5) in the Pharmaceuticals Major industry is significantly better than the same rating for MGTX (100) in the Biotechnology industry. This means that SPRO’s stock grew significantly faster than MGTX’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
MGTXSPRO
RSI
ODDS (%)
N/A
Bearish Trend 2 days ago
73%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
90%
Bearish Trend 2 days ago
83%
Momentum
ODDS (%)
Bearish Trend 2 days ago
82%
Bullish Trend 2 days ago
72%
MACD
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
70%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
81%
Bullish Trend 2 days ago
74%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
79%
Bullish Trend 2 days ago
74%
Advances
ODDS (%)
Bullish Trend 3 days ago
82%
Bullish Trend 2 days ago
70%
Declines
ODDS (%)
Bearish Trend 10 days ago
82%
Bearish Trend 10 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
82%
Aroon
ODDS (%)
Bullish Trend 2 days ago
76%
N/A
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MGTX
Daily Signal:
Gain/Loss:
SPRO
Daily Signal:
Gain/Loss:
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MGTX and

Correlation & Price change

A.I.dvisor indicates that over the last year, MGTX has been loosely correlated with IDYA. These tickers have moved in lockstep 48% of the time. This A.I.-generated data suggests there is some statistical probability that if MGTX jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To MGTX
1D Price
Change %
MGTX100%
-2.70%
IDYA - MGTX
48%
Loosely correlated
-0.19%
RGNX - MGTX
45%
Loosely correlated
+0.43%
NUVL - MGTX
45%
Loosely correlated
+0.91%
TRDA - MGTX
45%
Loosely correlated
+4.03%
AURA - MGTX
45%
Loosely correlated
-1.59%
More

SPRO and

Correlation & Price change

A.I.dvisor indicates that over the last year, SPRO has been loosely correlated with ASBP. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SPRO jumps, then ASBP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SPRO
1D Price
Change %
SPRO100%
+1.53%
ASBP - SPRO
58%
Loosely correlated
-7.66%
CLGN - SPRO
39%
Loosely correlated
-0.53%
XENE - SPRO
32%
Poorly correlated
-0.60%
MGTX - SPRO
30%
Poorly correlated
-2.70%
MTVA - SPRO
30%
Poorly correlated
-7.91%
More