MDGL
Price
$598.91
Change
-$3.91 (-0.65%)
Updated
Dec 26 closing price
Capitalization
13.6B
67 days until earnings call
Intraday BUY SELL Signals
SYBX
Price
$1.19
Change
+$0.02 (+1.71%)
Updated
Dec 26, 04:59 PM (EDT)
Capitalization
13.69M
Intraday BUY SELL Signals
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MDGL vs SYBX

Header iconMDGL vs SYBX Comparison
Open Charts MDGL vs SYBXBanner chart's image
Madrigal Pharmaceuticals
Price$598.91
Change-$3.91 (-0.65%)
Volume$97.81K
Capitalization13.6B
Synlogic
Price$1.19
Change+$0.02 (+1.71%)
Volume$100
Capitalization13.69M
MDGL vs SYBX Comparison Chart in %
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VS
MDGL vs. SYBX commentary
Dec 27, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is MDGL is a Buy and SYBX is a Buy.

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COMPARISON
Comparison
Dec 27, 2025
Stock price -- (MDGL: $602.82 vs. SYBX: $1.17)
Brand notoriety: MDGL and SYBX are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: MDGL: 28% vs. SYBX: 14%
Market capitalization -- MDGL: $13.69B vs. SYBX: $13.69M
MDGL [@Biotechnology] is valued at $13.69B. SYBX’s [@Biotechnology] market capitalization is $13.69M. The market cap for tickers in the [@Biotechnology] industry ranges from $117.47B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

MDGL’s FA Score shows that 1 FA rating(s) are green whileSYBX’s FA Score has 1 green FA rating(s).

  • MDGL’s FA Score: 1 green, 4 red.
  • SYBX’s FA Score: 1 green, 4 red.
According to our system of comparison, MDGL is a better buy in the long-term than SYBX.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

MDGL’s TA Score shows that 4 TA indicator(s) are bullish while SYBX’s TA Score has 6 bullish TA indicator(s).

  • MDGL’s TA Score: 4 bullish, 4 bearish.
  • SYBX’s TA Score: 6 bullish, 2 bearish.
According to our system of comparison, SYBX is a better buy in the short-term than MDGL.

Price Growth

MDGL (@Biotechnology) experienced а +10.37% price change this week, while SYBX (@Biotechnology) price change was +5.41% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.37%. For the same industry, the average monthly price growth was +0.28%, and the average quarterly price growth was +55.43%.

Reported Earning Dates

MDGL is expected to report earnings on Mar 04, 2026.

Industries' Descriptions

@Biotechnology (+0.37% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
MDGL($13.6B) has a higher market cap than SYBX($13.7M). MDGL YTD gains are higher at: 94.092 vs. SYBX (-16.429). SYBX has higher annual earnings (EBITDA): -11.43M vs. MDGL (-270.14M). MDGL has more cash in the bank: 1.11B vs. SYBX (15.6M). SYBX has less debt than MDGL: SYBX (0) vs MDGL (346M). MDGL has higher revenues than SYBX: MDGL (741M) vs SYBX (8K).
MDGLSYBXMDGL / SYBX
Capitalization13.6B13.7M99,270%
EBITDA-270.14M-11.43M2,363%
Gain YTD94.092-16.429-573%
P/E RatioN/A6.36-
Revenue741M8K9,262,500%
Total Cash1.11B15.6M7,115%
Total Debt346M0-
FUNDAMENTALS RATINGS
MDGL vs SYBX: Fundamental Ratings
MDGL
SYBX
OUTLOOK RATING
1..100
612
VALUATION
overvalued / fair valued / undervalued
1..100
65
Fair valued
82
Overvalued
PROFIT vs RISK RATING
1..100
15100
SMR RATING
1..100
9796
PRICE GROWTH RATING
1..100
3786
P/E GROWTH RATING
1..100
10022
SEASONALITY SCORE
1..100
7585

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

MDGL's Valuation (65) in the Pharmaceuticals Other industry is in the same range as SYBX (82) in the Biotechnology industry. This means that MDGL’s stock grew similarly to SYBX’s over the last 12 months.

MDGL's Profit vs Risk Rating (15) in the Pharmaceuticals Other industry is significantly better than the same rating for SYBX (100) in the Biotechnology industry. This means that MDGL’s stock grew significantly faster than SYBX’s over the last 12 months.

SYBX's SMR Rating (96) in the Biotechnology industry is in the same range as MDGL (97) in the Pharmaceuticals Other industry. This means that SYBX’s stock grew similarly to MDGL’s over the last 12 months.

MDGL's Price Growth Rating (37) in the Pharmaceuticals Other industry is somewhat better than the same rating for SYBX (86) in the Biotechnology industry. This means that MDGL’s stock grew somewhat faster than SYBX’s over the last 12 months.

SYBX's P/E Growth Rating (22) in the Biotechnology industry is significantly better than the same rating for MDGL (100) in the Pharmaceuticals Other industry. This means that SYBX’s stock grew significantly faster than MDGL’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
MDGLSYBX
RSI
ODDS (%)
Bearish Trend 1 day ago
90%
Bullish Trend 3 days ago
86%
Stochastic
ODDS (%)
Bearish Trend 1 day ago
86%
Bullish Trend 3 days ago
86%
Momentum
ODDS (%)
Bullish Trend 1 day ago
77%
Bullish Trend 3 days ago
81%
MACD
ODDS (%)
Bullish Trend 1 day ago
79%
Bullish Trend 3 days ago
82%
TrendWeek
ODDS (%)
Bullish Trend 1 day ago
78%
Bullish Trend 3 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 1 day ago
77%
Bearish Trend 3 days ago
88%
Advances
ODDS (%)
Bullish Trend 5 days ago
78%
Bullish Trend 8 days ago
82%
Declines
ODDS (%)
Bearish Trend 9 days ago
79%
Bearish Trend 4 days ago
87%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
76%
Bullish Trend 3 days ago
79%
Aroon
ODDS (%)
Bullish Trend 1 day ago
80%
Bearish Trend 3 days ago
90%
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MDGL
Daily Signal:
Gain/Loss:
SYBX
Daily Signal:
Gain/Loss:
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MDGL and

Correlation & Price change

A.I.dvisor indicates that over the last year, MDGL has been loosely correlated with ALXO. These tickers have moved in lockstep 56% of the time. This A.I.-generated data suggests there is some statistical probability that if MDGL jumps, then ALXO could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To MDGL
1D Price
Change %
MDGL100%
-0.65%
ALXO - MDGL
56%
Loosely correlated
-2.21%
IPHA - MDGL
44%
Loosely correlated
+2.94%
GHRS - MDGL
43%
Loosely correlated
-1.45%
LCTX - MDGL
43%
Loosely correlated
-1.79%
CVM - MDGL
43%
Loosely correlated
+0.64%
More

SYBX and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYBX has been loosely correlated with NEUP. These tickers have moved in lockstep 64% of the time. This A.I.-generated data suggests there is some statistical probability that if SYBX jumps, then NEUP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYBX
1D Price
Change %
SYBX100%
N/A
NEUP - SYBX
64%
Loosely correlated
+0.53%
BTAI - SYBX
37%
Loosely correlated
-1.16%
SBHMY - SYBX
34%
Loosely correlated
N/A
MDGL - SYBX
31%
Poorly correlated
+0.10%
LITS - SYBX
30%
Poorly correlated
+1.46%
More