MDGL
Price
$602.82
Change
+$0.61 (+0.10%)
Updated
Dec 24 closing price
Capitalization
13.69B
68 days until earnings call
Intraday BUY SELL Signals
RPRX
Price
$39.25
Change
-$0.14 (-0.36%)
Updated
Dec 24 closing price
Capitalization
16.77B
53 days until earnings call
Intraday BUY SELL Signals
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MDGL vs RPRX

Header iconMDGL vs RPRX Comparison
Open Charts MDGL vs RPRXBanner chart's image
Madrigal Pharmaceuticals
Price$602.82
Change+$0.61 (+0.10%)
Volume$103.02K
Capitalization13.69B
Royalty Pharma
Price$39.25
Change-$0.14 (-0.36%)
Volume$1.09M
Capitalization16.77B
MDGL vs RPRX Comparison Chart in %
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MDGL vs. RPRX commentary
Dec 26, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is MDGL is a Hold and RPRX is a Hold.

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COMPARISON
Comparison
Dec 26, 2025
Stock price -- (MDGL: $602.82 vs. RPRX: $39.25)
Brand notoriety: MDGL and RPRX are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: MDGL: 28% vs. RPRX: 26%
Market capitalization -- MDGL: $13.69B vs. RPRX: $16.77B
MDGL [@Biotechnology] is valued at $13.69B. RPRX’s [@Biotechnology] market capitalization is $16.77B. The market cap for tickers in the [@Biotechnology] industry ranges from $117.47B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

MDGL’s FA Score shows that 1 FA rating(s) are green whileRPRX’s FA Score has 2 green FA rating(s).

  • MDGL’s FA Score: 1 green, 4 red.
  • RPRX’s FA Score: 2 green, 3 red.
According to our system of comparison, RPRX is a better buy in the long-term than MDGL.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

MDGL’s TA Score shows that 4 TA indicator(s) are bullish while RPRX’s TA Score has 3 bullish TA indicator(s).

  • MDGL’s TA Score: 4 bullish, 4 bearish.
  • RPRX’s TA Score: 3 bullish, 2 bearish.
According to our system of comparison, both MDGL and RPRX are a good buy in the short-term.

Price Growth

MDGL (@Biotechnology) experienced а +10.37% price change this week, while RPRX (@Biotechnology) price change was +2.45% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.88%. For the same industry, the average monthly price growth was +4.46%, and the average quarterly price growth was +55.39%.

Reported Earning Dates

MDGL is expected to report earnings on Mar 04, 2026.

RPRX is expected to report earnings on Feb 17, 2026.

Industries' Descriptions

@Biotechnology (+2.88% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
RPRX($16.8B) has a higher market cap than MDGL($13.7B). MDGL YTD gains are higher at: 95.359 vs. RPRX (56.865). RPRX has higher annual earnings (EBITDA): 1.59B vs. MDGL (-270.14M). RPRX has more cash in the bank: 1.82B vs. MDGL (1.11B). MDGL has less debt than RPRX: MDGL (346M) vs RPRX (8.95B). RPRX has higher revenues than MDGL: RPRX (2.35B) vs MDGL (741M).
MDGLRPRXMDGL / RPRX
Capitalization13.7B16.8B82%
EBITDA-270.14M1.59B-17%
Gain YTD95.35956.865168%
P/E RatioN/A22.43-
Revenue741M2.35B32%
Total Cash1.11B1.82B61%
Total Debt346M8.95B4%
FUNDAMENTALS RATINGS
MDGL vs RPRX: Fundamental Ratings
MDGL
RPRX
OUTLOOK RATING
1..100
6768
VALUATION
overvalued / fair valued / undervalued
1..100
65
Fair valued
2
Undervalued
PROFIT vs RISK RATING
1..100
1591
SMR RATING
1..100
9795
PRICE GROWTH RATING
1..100
3745
P/E GROWTH RATING
1..100
1007
SEASONALITY SCORE
1..100
n/a50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

RPRX's Valuation (2) in the Pharmaceuticals Major industry is somewhat better than the same rating for MDGL (65) in the Pharmaceuticals Other industry. This means that RPRX’s stock grew somewhat faster than MDGL’s over the last 12 months.

MDGL's Profit vs Risk Rating (15) in the Pharmaceuticals Other industry is significantly better than the same rating for RPRX (91) in the Pharmaceuticals Major industry. This means that MDGL’s stock grew significantly faster than RPRX’s over the last 12 months.

RPRX's SMR Rating (95) in the Pharmaceuticals Major industry is in the same range as MDGL (97) in the Pharmaceuticals Other industry. This means that RPRX’s stock grew similarly to MDGL’s over the last 12 months.

MDGL's Price Growth Rating (37) in the Pharmaceuticals Other industry is in the same range as RPRX (45) in the Pharmaceuticals Major industry. This means that MDGL’s stock grew similarly to RPRX’s over the last 12 months.

RPRX's P/E Growth Rating (7) in the Pharmaceuticals Major industry is significantly better than the same rating for MDGL (100) in the Pharmaceuticals Other industry. This means that RPRX’s stock grew significantly faster than MDGL’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
MDGLRPRX
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
N/A
Stochastic
ODDS (%)
Bearish Trend 2 days ago
84%
Bearish Trend 2 days ago
60%
Momentum
ODDS (%)
Bullish Trend 2 days ago
73%
Bullish Trend 2 days ago
52%
MACD
ODDS (%)
Bullish Trend 2 days ago
74%
Bullish Trend 2 days ago
49%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 2 days ago
47%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
77%
Bullish Trend 2 days ago
48%
Advances
ODDS (%)
Bullish Trend 4 days ago
78%
Bullish Trend 3 days ago
49%
Declines
ODDS (%)
Bearish Trend 8 days ago
79%
Bearish Trend 9 days ago
60%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
N/A
Aroon
ODDS (%)
Bullish Trend 2 days ago
80%
N/A
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MDGL
Daily Signal:
Gain/Loss:
RPRX
Daily Signal:
Gain/Loss:
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MDGL and

Correlation & Price change

A.I.dvisor indicates that over the last year, MDGL has been loosely correlated with ALXO. These tickers have moved in lockstep 56% of the time. This A.I.-generated data suggests there is some statistical probability that if MDGL jumps, then ALXO could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To MDGL
1D Price
Change %
MDGL100%
+0.10%
ALXO - MDGL
56%
Loosely correlated
-2.86%
IPHA - MDGL
44%
Loosely correlated
-3.41%
GHRS - MDGL
43%
Loosely correlated
+0.27%
LCTX - MDGL
43%
Loosely correlated
+1.20%
CVM - MDGL
43%
Loosely correlated
+5.41%
More

RPRX and

Correlation & Price change

A.I.dvisor indicates that over the last year, RPRX has been loosely correlated with AXON. These tickers have moved in lockstep 48% of the time. This A.I.-generated data suggests there is some statistical probability that if RPRX jumps, then AXON could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To RPRX
1D Price
Change %
RPRX100%
-0.36%
AXON - RPRX
48%
Loosely correlated
+0.02%
MDGL - RPRX
31%
Poorly correlated
+0.10%
ARRY - RPRX
30%
Poorly correlated
+2.10%
QURE - RPRX
29%
Poorly correlated
+4.18%
SLGL - RPRX
28%
Poorly correlated
+0.83%
More