LGND
Price
$104.48
Change
+$1.97 (+1.92%)
Updated
May 9 closing price
Capitalization
2.01B
93 days until earnings call
SYRE
Price
$14.10
Change
+$1.24 (+9.64%)
Updated
May 9 closing price
Capitalization
849.89M
82 days until earnings call
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LGND vs SYRE

Header iconLGND vs SYRE Comparison
Open Charts LGND vs SYREBanner chart's image
Ligand Pharmaceuticals
Price$104.48
Change+$1.97 (+1.92%)
Volume$148.63K
Capitalization2.01B
Spyre Therapeutics
Price$14.10
Change+$1.24 (+9.64%)
Volume$966.72K
Capitalization849.89M
LGND vs SYRE Comparison Chart
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LGND
Daily Signalchanged days ago
Gain/Loss if bought
Show more...
SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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VS
LGND vs. SYRE commentary
May 11, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is LGND is a Hold and SYRE is a StrongBuy.

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COMPARISON
Comparison
May 11, 2025
Stock price -- (LGND: $104.48 vs. SYRE: $14.10)
Brand notoriety: LGND and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: LGND: 120% vs. SYRE: 135%
Market capitalization -- LGND: $2.01B vs. SYRE: $849.89M
LGND [@Biotechnology] is valued at $2.01B. SYRE’s [@Biotechnology] market capitalization is $849.89M. The market cap for tickers in the [@Biotechnology] industry ranges from $296.96B to $0. The average market capitalization across the [@Biotechnology] industry is $2.13B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

LGND’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • LGND’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, LGND is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

LGND’s TA Score shows that 4 TA indicator(s) are bullish while SYRE’s TA Score has 4 bullish TA indicator(s).

  • LGND’s TA Score: 4 bullish, 7 bearish.
  • SYRE’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, SYRE is a better buy in the short-term than LGND.

Price Growth

LGND (@Biotechnology) experienced а -4.49% price change this week, while SYRE (@Biotechnology) price change was -6.68% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -6.25%. For the same industry, the average monthly price growth was +9.40%, and the average quarterly price growth was -13.49%.

Reported Earning Dates

LGND is expected to report earnings on Aug 11, 2025.

SYRE is expected to report earnings on Jul 31, 2025.

Industries' Descriptions

@Biotechnology (-6.25% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
LGND($2.01B) has a higher market cap than SYRE($850M). LGND has higher P/E ratio than SYRE: LGND (46.19) vs SYRE (1.68). LGND YTD gains are higher at: -2.492 vs. SYRE (-39.433). LGND has higher annual earnings (EBITDA): 40.8M vs. SYRE (-208.57M). SYRE has more cash in the bank: 603M vs. LGND (256M). SYRE has less debt than LGND: SYRE (0) vs LGND (7.11M). LGND has higher revenues than SYRE: LGND (167M) vs SYRE (0).
LGNDSYRELGND / SYRE
Capitalization2.01B850M237%
EBITDA40.8M-208.57M-20%
Gain YTD-2.492-39.4336%
P/E Ratio46.191.682,742%
Revenue167M0-
Total Cash256M603M42%
Total Debt7.11M0-
FUNDAMENTALS RATINGS
LGND vs SYRE: Fundamental Ratings
LGND
SYRE
OUTLOOK RATING
1..100
7022
VALUATION
overvalued / fair valued / undervalued
1..100
77
Overvalued
76
Overvalued
PROFIT vs RISK RATING
1..100
58100
SMR RATING
1..100
9198
PRICE GROWTH RATING
1..100
5565
P/E GROWTH RATING
1..100
9079
SEASONALITY SCORE
1..100
n/an/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SYRE's Valuation (76) in the Pharmaceuticals Major industry is in the same range as LGND (77) in the Biotechnology industry. This means that SYRE’s stock grew similarly to LGND’s over the last 12 months.

LGND's Profit vs Risk Rating (58) in the Biotechnology industry is somewhat better than the same rating for SYRE (100) in the Pharmaceuticals Major industry. This means that LGND’s stock grew somewhat faster than SYRE’s over the last 12 months.

LGND's SMR Rating (91) in the Biotechnology industry is in the same range as SYRE (98) in the Pharmaceuticals Major industry. This means that LGND’s stock grew similarly to SYRE’s over the last 12 months.

LGND's Price Growth Rating (55) in the Biotechnology industry is in the same range as SYRE (65) in the Pharmaceuticals Major industry. This means that LGND’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's P/E Growth Rating (79) in the Pharmaceuticals Major industry is in the same range as LGND (90) in the Biotechnology industry. This means that SYRE’s stock grew similarly to LGND’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
LGNDSYRE
RSI
ODDS (%)
Bullish Trend 2 days ago
69%
Bullish Trend 2 days ago
81%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
76%
Bullish Trend 2 days ago
84%
Momentum
ODDS (%)
Bearish Trend 2 days ago
77%
Bearish Trend 2 days ago
90%
MACD
ODDS (%)
Bearish Trend 2 days ago
89%
Bullish Trend 2 days ago
77%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
75%
Bearish Trend 2 days ago
88%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
73%
Bullish Trend 2 days ago
83%
Advances
ODDS (%)
Bullish Trend 12 days ago
73%
Bullish Trend 2 days ago
84%
Declines
ODDS (%)
Bearish Trend 5 days ago
75%
Bearish Trend 5 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
82%
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
Bullish Trend 2 days ago
77%
Bearish Trend 2 days ago
88%
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LGND
Daily Signalchanged days ago
Gain/Loss if bought
Show more...
SYRE
Daily Signalchanged days ago
Gain/Loss if bought
Show more...
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LGND and

Correlation & Price change

A.I.dvisor indicates that over the last year, LGND has been loosely correlated with ACLX. These tickers have moved in lockstep 51% of the time. This A.I.-generated data suggests there is some statistical probability that if LGND jumps, then ACLX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To LGND
1D Price
Change %
LGND100%
+1.92%
ACLX - LGND
51%
Loosely correlated
+2.29%
ROIV - LGND
46%
Loosely correlated
-3.54%
CRNX - LGND
46%
Loosely correlated
-6.18%
DNLI - LGND
45%
Loosely correlated
-0.42%
SYRE - LGND
44%
Loosely correlated
+9.64%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with BEAM. These tickers have moved in lockstep 54% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then BEAM could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+9.64%
BEAM - SYRE
54%
Loosely correlated
+0.93%
APGE - SYRE
53%
Loosely correlated
-1.38%
CGON - SYRE
52%
Loosely correlated
-1.62%
RGNX - SYRE
49%
Loosely correlated
+5.17%
ACLX - SYRE
49%
Loosely correlated
+2.29%
More