KRYS
Price
$138.88
Change
-$3.70 (-2.60%)
Updated
Jun 27 closing price
Capitalization
4.01B
42 days until earnings call
VRTX
Price
$441.30
Change
-$2.10 (-0.47%)
Updated
Jun 27 closing price
Capitalization
113.32B
31 days until earnings call
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KRYS vs VRTX

Header iconKRYS vs VRTX Comparison
Open Charts KRYS vs VRTXBanner chart's image
Krystal Biotech
Price$138.88
Change-$3.70 (-2.60%)
Volume$418.51K
Capitalization4.01B
Vertex Pharmaceuticals
Price$441.30
Change-$2.10 (-0.47%)
Volume$3.62M
Capitalization113.32B
KRYS vs VRTX Comparison Chart in %
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KRYS
Daily Signalchanged days ago
Gain/Loss if bought
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VRTX
Daily Signalchanged days ago
Gain/Loss if bought
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KRYS vs. VRTX commentary
Jun 30, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KRYS is a Buy and VRTX is a Buy.

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COMPARISON
Comparison
Jun 30, 2025
Stock price -- (KRYS: $138.88 vs. VRTX: $441.30)
Brand notoriety: KRYS and VRTX are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KRYS: 112% vs. VRTX: 210%
Market capitalization -- KRYS: $4.01B vs. VRTX: $113.32B
KRYS [@Biotechnology] is valued at $4.01B. VRTX’s [@Biotechnology] market capitalization is $113.32B. The market cap for tickers in the [@Biotechnology] industry ranges from $304.6B to $0. The average market capitalization across the [@Biotechnology] industry is $2.32B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KRYS’s FA Score shows that 0 FA rating(s) are green whileVRTX’s FA Score has 0 green FA rating(s).

  • KRYS’s FA Score: 0 green, 5 red.
  • VRTX’s FA Score: 0 green, 5 red.
According to our system of comparison, VRTX is a better buy in the long-term than KRYS.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KRYS’s TA Score shows that 4 TA indicator(s) are bullish while VRTX’s TA Score has 4 bullish TA indicator(s).

  • KRYS’s TA Score: 4 bullish, 5 bearish.
  • VRTX’s TA Score: 4 bullish, 3 bearish.
According to our system of comparison, VRTX is a better buy in the short-term than KRYS.

Price Growth

KRYS (@Biotechnology) experienced а +4.85% price change this week, while VRTX (@Biotechnology) price change was +0.10% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.13%. For the same industry, the average monthly price growth was +31.22%, and the average quarterly price growth was +12.91%.

Reported Earning Dates

KRYS is expected to report earnings on Aug 11, 2025.

VRTX is expected to report earnings on Jul 31, 2025.

Industries' Descriptions

@Biotechnology (+4.13% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
VRTX($113B) has a higher market cap than KRYS($4.01B). KRYS (33.30) and VRTX (32.17) have similar P/E ratio . VRTX YTD gains are higher at: 9.585 vs. KRYS (-11.349). KRYS has higher annual earnings (EBITDA): 140M vs. VRTX (-74.9M). VRTX has more cash in the bank: 6.2B vs. KRYS (617M). KRYS has less debt than VRTX: KRYS (9.66M) vs VRTX (1.65B). VRTX has higher revenues than KRYS: VRTX (11.1B) vs KRYS (333M).
KRYSVRTXKRYS / VRTX
Capitalization4.01B113B4%
EBITDA140M-74.9M-187%
Gain YTD-11.3499.585-118%
P/E Ratio33.3032.17104%
Revenue333M11.1B3%
Total Cash617M6.2B10%
Total Debt9.66M1.65B1%
FUNDAMENTALS RATINGS
KRYS vs VRTX: Fundamental Ratings
KRYS
VRTX
OUTLOOK RATING
1..100
3950
VALUATION
overvalued / fair valued / undervalued
1..100
71
Overvalued
77
Overvalued
PROFIT vs RISK RATING
1..100
4134
SMR RATING
1..100
5791
PRICE GROWTH RATING
1..100
6259
P/E GROWTH RATING
1..100
9834
SEASONALITY SCORE
1..100
n/a17

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

KRYS's Valuation (71) in the Pharmaceuticals Major industry is in the same range as VRTX (77) in the Biotechnology industry. This means that KRYS’s stock grew similarly to VRTX’s over the last 12 months.

VRTX's Profit vs Risk Rating (34) in the Biotechnology industry is in the same range as KRYS (41) in the Pharmaceuticals Major industry. This means that VRTX’s stock grew similarly to KRYS’s over the last 12 months.

KRYS's SMR Rating (57) in the Pharmaceuticals Major industry is somewhat better than the same rating for VRTX (91) in the Biotechnology industry. This means that KRYS’s stock grew somewhat faster than VRTX’s over the last 12 months.

VRTX's Price Growth Rating (59) in the Biotechnology industry is in the same range as KRYS (62) in the Pharmaceuticals Major industry. This means that VRTX’s stock grew similarly to KRYS’s over the last 12 months.

VRTX's P/E Growth Rating (34) in the Biotechnology industry is somewhat better than the same rating for KRYS (98) in the Pharmaceuticals Major industry. This means that VRTX’s stock grew somewhat faster than KRYS’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KRYSVRTX
RSI
ODDS (%)
Bullish Trend 4 days ago
90%
N/A
Stochastic
ODDS (%)
Bearish Trend 4 days ago
86%
Bullish Trend 4 days ago
64%
Momentum
ODDS (%)
Bearish Trend 4 days ago
81%
Bearish Trend 4 days ago
42%
MACD
ODDS (%)
Bullish Trend 4 days ago
80%
Bullish Trend 4 days ago
65%
TrendWeek
ODDS (%)
Bullish Trend 4 days ago
77%
Bullish Trend 4 days ago
57%
TrendMonth
ODDS (%)
Bullish Trend 4 days ago
78%
Bearish Trend 4 days ago
43%
Advances
ODDS (%)
Bullish Trend 11 days ago
77%
Bullish Trend 19 days ago
59%
Declines
ODDS (%)
Bearish Trend 14 days ago
76%
Bearish Trend 4 days ago
44%
BollingerBands
ODDS (%)
Bearish Trend 4 days ago
80%
Bearish Trend 4 days ago
53%
Aroon
ODDS (%)
Bullish Trend 4 days ago
75%
Bullish Trend 4 days ago
61%
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KRYS
Daily Signalchanged days ago
Gain/Loss if bought
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VRTX
Daily Signalchanged days ago
Gain/Loss if bought
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KRYS and

Correlation & Price change

A.I.dvisor indicates that over the last year, KRYS has been loosely correlated with XNCR. These tickers have moved in lockstep 54% of the time. This A.I.-generated data suggests there is some statistical probability that if KRYS jumps, then XNCR could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KRYS
1D Price
Change %
KRYS100%
-2.60%
XNCR - KRYS
54%
Loosely correlated
-3.10%
IDYA - KRYS
54%
Loosely correlated
-4.13%
CRNX - KRYS
54%
Loosely correlated
-0.10%
ACLX - KRYS
54%
Loosely correlated
+0.90%
CGON - KRYS
54%
Loosely correlated
-0.46%
More

VRTX and

Correlation & Price change

A.I.dvisor indicates that over the last year, VRTX has been loosely correlated with KRYS. These tickers have moved in lockstep 49% of the time. This A.I.-generated data suggests there is some statistical probability that if VRTX jumps, then KRYS could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To VRTX
1D Price
Change %
VRTX100%
-0.47%
KRYS - VRTX
49%
Loosely correlated
-2.60%
SNDX - VRTX
40%
Loosely correlated
-2.80%
TECH - VRTX
40%
Loosely correlated
-1.82%
IDYA - VRTX
39%
Loosely correlated
-4.13%
RGNX - VRTX
39%
Loosely correlated
-4.11%
More