KPTI
Price
$7.15
Change
+$0.15 (+2.14%)
Updated
Dec 12, 11:41 AM (EDT)
Capitalization
119.36M
Intraday BUY SELL Signals
XNCR
Price
$17.06
Change
-$0.10 (-0.58%)
Updated
Dec 11 closing price
Capitalization
1.22B
82 days until earnings call
Intraday BUY SELL Signals
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KPTI vs XNCR

Header iconKPTI vs XNCR Comparison
Open Charts KPTI vs XNCRBanner chart's image
Karyopharm Therapeutics
Price$7.15
Change+$0.15 (+2.14%)
Volume$1.1K
Capitalization119.36M
Xencor
Price$17.06
Change-$0.10 (-0.58%)
Volume$611.38K
Capitalization1.22B
KPTI vs XNCR Comparison Chart in %
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VS
KPTI vs. XNCR commentary
Dec 13, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KPTI is a StrongBuy and XNCR is a Hold.

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COMPARISON
Comparison
Dec 13, 2025
Stock price -- (KPTI: $7.00 vs. XNCR: $17.06)
Brand notoriety: KPTI and XNCR are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KPTI: 266% vs. XNCR: 55%
Market capitalization -- KPTI: $119.36M vs. XNCR: $1.22B
KPTI [@Biotechnology] is valued at $119.36M. XNCR’s [@Biotechnology] market capitalization is $1.22B. The market cap for tickers in the [@Biotechnology] industry ranges from $113.14B to $0. The average market capitalization across the [@Biotechnology] industry is $2.21B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KPTI’s FA Score shows that 1 FA rating(s) are green whileXNCR’s FA Score has 1 green FA rating(s).

  • KPTI’s FA Score: 1 green, 4 red.
  • XNCR’s FA Score: 1 green, 4 red.
According to our system of comparison, both KPTI and XNCR are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KPTI’s TA Score shows that 6 TA indicator(s) are bullish while XNCR’s TA Score has 2 bullish TA indicator(s).

  • KPTI’s TA Score: 6 bullish, 4 bearish.
  • XNCR’s TA Score: 2 bullish, 6 bearish.
According to our system of comparison, KPTI is a better buy in the short-term than XNCR.

Price Growth

KPTI (@Biotechnology) experienced а +18.44% price change this week, while XNCR (@Biotechnology) price change was -5.95% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.68%. For the same industry, the average monthly price growth was +4.10%, and the average quarterly price growth was +64.61%.

Reported Earning Dates

XNCR is expected to report earnings on Mar 04, 2026.

Industries' Descriptions

@Biotechnology (+0.68% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
XNCR($1.22B) has a higher market cap than KPTI($119M). XNCR YTD gains are higher at: -25.762 vs. KPTI (-30.997). KPTI has higher annual earnings (EBITDA): -78.44M vs. XNCR (-125.38M). XNCR has more cash in the bank: 444M vs. KPTI (51.7M). XNCR has less debt than KPTI: XNCR (67.9M) vs KPTI (191M). XNCR has higher revenues than KPTI: XNCR (147M) vs KPTI (137M).
KPTIXNCRKPTI / XNCR
Capitalization119M1.22B10%
EBITDA-78.44M-125.38M63%
Gain YTD-30.997-25.762120%
P/E RatioN/AN/A-
Revenue137M147M93%
Total Cash51.7M444M12%
Total Debt191M67.9M281%
FUNDAMENTALS RATINGS
KPTI vs XNCR: Fundamental Ratings
KPTI
XNCR
OUTLOOK RATING
1..100
3016
VALUATION
overvalued / fair valued / undervalued
1..100
4
Undervalued
86
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10095
PRICE GROWTH RATING
1..100
4637
P/E GROWTH RATING
1..100
1005
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

KPTI's Valuation (4) in the Biotechnology industry is significantly better than the same rating for XNCR (86). This means that KPTI’s stock grew significantly faster than XNCR’s over the last 12 months.

KPTI's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as XNCR (100). This means that KPTI’s stock grew similarly to XNCR’s over the last 12 months.

XNCR's SMR Rating (95) in the Biotechnology industry is in the same range as KPTI (100). This means that XNCR’s stock grew similarly to KPTI’s over the last 12 months.

XNCR's Price Growth Rating (37) in the Biotechnology industry is in the same range as KPTI (46). This means that XNCR’s stock grew similarly to KPTI’s over the last 12 months.

XNCR's P/E Growth Rating (5) in the Biotechnology industry is significantly better than the same rating for KPTI (100). This means that XNCR’s stock grew significantly faster than KPTI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KPTIXNCR
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 3 days ago
88%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 3 days ago
80%
Momentum
ODDS (%)
Bullish Trend 2 days ago
81%
Bearish Trend 3 days ago
76%
MACD
ODDS (%)
Bullish Trend 2 days ago
87%
Bearish Trend 3 days ago
83%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
82%
Bearish Trend 3 days ago
84%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 3 days ago
72%
Advances
ODDS (%)
Bullish Trend 2 days ago
83%
Bullish Trend 9 days ago
72%
Declines
ODDS (%)
Bearish Trend 18 days ago
88%
Bearish Trend 23 days ago
81%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 3 days ago
71%
Aroon
ODDS (%)
Bullish Trend 2 days ago
75%
Bullish Trend 3 days ago
67%
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KPTI
Daily Signal:
Gain/Loss:
XNCR
Daily Signal:
Gain/Loss:
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KPTI and

Correlation & Price change

A.I.dvisor indicates that over the last year, KPTI has been loosely correlated with PGEN. These tickers have moved in lockstep 37% of the time. This A.I.-generated data suggests there is some statistical probability that if KPTI jumps, then PGEN could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KPTI
1D Price
Change %
KPTI100%
+8.02%
PGEN - KPTI
37%
Loosely correlated
+3.13%
SAVA - KPTI
36%
Loosely correlated
-3.37%
MGNX - KPTI
36%
Loosely correlated
+0.71%
ARRY - KPTI
35%
Loosely correlated
+3.85%
XENE - KPTI
35%
Loosely correlated
+0.51%
More

XNCR and

Correlation & Price change

A.I.dvisor indicates that over the last year, XNCR has been loosely correlated with CRNX. These tickers have moved in lockstep 60% of the time. This A.I.-generated data suggests there is some statistical probability that if XNCR jumps, then CRNX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To XNCR
1D Price
Change %
XNCR100%
-0.58%
CRNX - XNCR
60%
Loosely correlated
+2.60%
NUVL - XNCR
60%
Loosely correlated
+0.16%
KURA - XNCR
58%
Loosely correlated
-2.61%
IDYA - XNCR
58%
Loosely correlated
-0.24%
SYRE - XNCR
57%
Loosely correlated
-0.87%
More