KPTI
Price
$6.81
Change
-$0.67 (-8.96%)
Updated
Sep 24, 04:59 PM (EDT)
Capitalization
64.86M
XNCR
Price
$10.49
Change
+$0.17 (+1.65%)
Updated
Sep 24, 04:59 PM (EDT)
Capitalization
736.05M
47 days until earnings call
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KPTI vs XNCR

Header iconKPTI vs XNCR Comparison
Open Charts KPTI vs XNCRBanner chart's image
Karyopharm Therapeutics
Price$6.81
Change-$0.67 (-8.96%)
Volume$200
Capitalization64.86M
Xencor
Price$10.49
Change+$0.17 (+1.65%)
Volume$11.4K
Capitalization736.05M
KPTI vs XNCR Comparison Chart in %
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KPTI
Daily Signalchanged days ago
Gain/Loss if bought
Show more...
XNCR
Daily Signalchanged days ago
Gain/Loss if bought
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KPTI vs. XNCR commentary
Sep 25, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KPTI is a Hold and XNCR is a Buy.

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COMPARISON
Comparison
Sep 25, 2025
Stock price -- (KPTI: $7.48 vs. XNCR: $10.32)
Brand notoriety: KPTI and XNCR are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KPTI: 295% vs. XNCR: 134%
Market capitalization -- KPTI: $64.86M vs. XNCR: $736.05M
KPTI [@Biotechnology] is valued at $64.86M. XNCR’s [@Biotechnology] market capitalization is $736.05M. The market cap for tickers in the [@Biotechnology] industry ranges from $97.36B to $0. The average market capitalization across the [@Biotechnology] industry is $1.91B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KPTI’s FA Score shows that 1 FA rating(s) are green whileXNCR’s FA Score has 1 green FA rating(s).

  • KPTI’s FA Score: 1 green, 4 red.
  • XNCR’s FA Score: 1 green, 4 red.
According to our system of comparison, XNCR is a better buy in the long-term than KPTI.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KPTI’s TA Score shows that 4 TA indicator(s) are bullish while XNCR’s TA Score has 6 bullish TA indicator(s).

  • KPTI’s TA Score: 4 bullish, 4 bearish.
  • XNCR’s TA Score: 6 bullish, 4 bearish.
According to our system of comparison, XNCR is a better buy in the short-term than KPTI.

Price Growth

KPTI (@Biotechnology) experienced а +19.49% price change this week, while XNCR (@Biotechnology) price change was +19.72% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.90%. For the same industry, the average monthly price growth was +10.70%, and the average quarterly price growth was +54.52%.

Reported Earning Dates

XNCR is expected to report earnings on Nov 10, 2025.

Industries' Descriptions

@Biotechnology (+4.90% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
XNCR($736M) has a higher market cap than KPTI($64.9M). KPTI YTD gains are higher at: -26.265 vs. XNCR (-55.091). KPTI has higher annual earnings (EBITDA): -78.44M vs. XNCR (-125.38M). XNCR has more cash in the bank: 444M vs. KPTI (51.7M). XNCR has less debt than KPTI: XNCR (67.9M) vs KPTI (191M). XNCR has higher revenues than KPTI: XNCR (147M) vs KPTI (137M).
KPTIXNCRKPTI / XNCR
Capitalization64.9M736M9%
EBITDA-78.44M-125.38M63%
Gain YTD-26.265-55.09148%
P/E RatioN/AN/A-
Revenue137M147M93%
Total Cash51.7M444M12%
Total Debt191M67.9M281%
FUNDAMENTALS RATINGS
KPTI vs XNCR: Fundamental Ratings
KPTI
XNCR
OUTLOOK RATING
1..100
7024
VALUATION
overvalued / fair valued / undervalued
1..100
5
Undervalued
75
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10097
PRICE GROWTH RATING
1..100
5748
P/E GROWTH RATING
1..100
1006
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

KPTI's Valuation (5) in the Biotechnology industry is significantly better than the same rating for XNCR (75). This means that KPTI’s stock grew significantly faster than XNCR’s over the last 12 months.

KPTI's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as XNCR (100). This means that KPTI’s stock grew similarly to XNCR’s over the last 12 months.

XNCR's SMR Rating (97) in the Biotechnology industry is in the same range as KPTI (100). This means that XNCR’s stock grew similarly to KPTI’s over the last 12 months.

XNCR's Price Growth Rating (48) in the Biotechnology industry is in the same range as KPTI (57). This means that XNCR’s stock grew similarly to KPTI’s over the last 12 months.

XNCR's P/E Growth Rating (6) in the Biotechnology industry is significantly better than the same rating for KPTI (100). This means that XNCR’s stock grew significantly faster than KPTI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KPTIXNCR
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
88%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
86%
Bearish Trend 2 days ago
84%
Momentum
ODDS (%)
Bullish Trend 2 days ago
85%
Bullish Trend 3 days ago
72%
MACD
ODDS (%)
Bearish Trend 2 days ago
88%
Bullish Trend 2 days ago
70%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
83%
Bullish Trend 2 days ago
73%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
79%
Bullish Trend 2 days ago
72%
Advances
ODDS (%)
Bullish Trend 2 days ago
84%
Bullish Trend 3 days ago
71%
Declines
ODDS (%)
Bearish Trend 6 days ago
87%
Bearish Trend 16 days ago
82%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
82%
Aroon
ODDS (%)
N/A
Bullish Trend 2 days ago
62%
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KPTI
Daily Signalchanged days ago
Gain/Loss if bought
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XNCR
Daily Signalchanged days ago
Gain/Loss if bought
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KPTI and

Correlation & Price change

A.I.dvisor indicates that over the last year, KPTI has been loosely correlated with MGNX. These tickers have moved in lockstep 40% of the time. This A.I.-generated data suggests there is some statistical probability that if KPTI jumps, then MGNX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KPTI
1D Price
Change %
KPTI100%
+27.86%
MGNX - KPTI
40%
Loosely correlated
-4.05%
PGEN - KPTI
38%
Loosely correlated
-3.64%
XENE - KPTI
32%
Poorly correlated
-0.11%
XNCR - KPTI
32%
Poorly correlated
-0.67%
PDSB - KPTI
32%
Poorly correlated
-2.78%
More

XNCR and

Correlation & Price change

A.I.dvisor indicates that over the last year, XNCR has been loosely correlated with CRNX. These tickers have moved in lockstep 63% of the time. This A.I.-generated data suggests there is some statistical probability that if XNCR jumps, then CRNX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To XNCR
1D Price
Change %
XNCR100%
-0.67%
CRNX - XNCR
63%
Loosely correlated
+6.35%
DYN - XNCR
58%
Loosely correlated
-1.86%
SYRE - XNCR
57%
Loosely correlated
+4.77%
CGON - XNCR
56%
Loosely correlated
-0.92%
ERAS - XNCR
55%
Loosely correlated
-0.56%
More