KPTI
Price
$5.62
Change
+$0.12 (+2.18%)
Updated
Nov 14, 12:32 PM (EDT)
Capitalization
93.78M
Intraday BUY SELL Signals
XENE
Price
$40.76
Change
+$0.72 (+1.80%)
Updated
Nov 14, 04:59 PM (EDT)
Capitalization
3.09B
104 days until earnings call
Intraday BUY SELL Signals
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KPTI vs XENE

Header iconKPTI vs XENE Comparison
Open Charts KPTI vs XENEBanner chart's image
Karyopharm Therapeutics
Price$5.62
Change+$0.12 (+2.18%)
Volume$400
Capitalization93.78M
Xenon Pharmaceuticals
Price$40.76
Change+$0.72 (+1.80%)
Volume$13.17K
Capitalization3.09B
KPTI vs XENE Comparison Chart in %
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VS
KPTI vs. XENE commentary
Nov 14, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KPTI is a Hold and XENE is a Buy.

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COMPARISON
Comparison
Nov 14, 2025
Stock price -- (KPTI: $5.50 vs. XENE: $40.04)
Brand notoriety: KPTI and XENE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KPTI: 30% vs. XENE: 125%
Market capitalization -- KPTI: $93.78M vs. XENE: $3.09B
KPTI [@Biotechnology] is valued at $93.78M. XENE’s [@Biotechnology] market capitalization is $3.09B. The market cap for tickers in the [@Biotechnology] industry ranges from $110.25B to $0. The average market capitalization across the [@Biotechnology] industry is $2.11B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KPTI’s FA Score shows that 1 FA rating(s) are green whileXENE’s FA Score has 1 green FA rating(s).

  • KPTI’s FA Score: 1 green, 4 red.
  • XENE’s FA Score: 1 green, 4 red.
According to our system of comparison, XENE is a better buy in the long-term than KPTI.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KPTI’s TA Score shows that 4 TA indicator(s) are bullish while XENE’s TA Score has 5 bullish TA indicator(s).

  • KPTI’s TA Score: 4 bullish, 5 bearish.
  • XENE’s TA Score: 5 bullish, 4 bearish.
According to our system of comparison, XENE is a better buy in the short-term than KPTI.

Price Growth

KPTI (@Biotechnology) experienced а +5.36% price change this week, while XENE (@Biotechnology) price change was +4.54% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +3.64%. For the same industry, the average monthly price growth was -3.56%, and the average quarterly price growth was +66.73%.

Reported Earning Dates

XENE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+3.64% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
XENE($3.09B) has a higher market cap than KPTI($93.8M). XENE YTD gains are higher at: 2.143 vs. KPTI (-45.783). KPTI has higher annual earnings (EBITDA): -78.44M vs. XENE (-315.5M). XENE has more cash in the bank: 488M vs. KPTI (51.7M). XENE has less debt than KPTI: XENE (8.72M) vs KPTI (191M). KPTI has higher revenues than XENE: KPTI (137M) vs XENE (7.5M).
KPTIXENEKPTI / XENE
Capitalization93.8M3.09B3%
EBITDA-78.44M-315.5M25%
Gain YTD-45.7832.143-2,137%
P/E RatioN/AN/A-
Revenue137M7.5M1,827%
Total Cash51.7M488M11%
Total Debt191M8.72M2,192%
FUNDAMENTALS RATINGS
KPTI vs XENE: Fundamental Ratings
KPTI
XENE
OUTLOOK RATING
1..100
6661
VALUATION
overvalued / fair valued / undervalued
1..100
4
Undervalued
73
Overvalued
PROFIT vs RISK RATING
1..100
10035
SMR RATING
1..100
10096
PRICE GROWTH RATING
1..100
5951
P/E GROWTH RATING
1..100
1005
SEASONALITY SCORE
1..100
n/a75

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

KPTI's Valuation (4) in the Biotechnology industry is significantly better than the same rating for XENE (73). This means that KPTI’s stock grew significantly faster than XENE’s over the last 12 months.

XENE's Profit vs Risk Rating (35) in the Biotechnology industry is somewhat better than the same rating for KPTI (100). This means that XENE’s stock grew somewhat faster than KPTI’s over the last 12 months.

XENE's SMR Rating (96) in the Biotechnology industry is in the same range as KPTI (100). This means that XENE’s stock grew similarly to KPTI’s over the last 12 months.

XENE's Price Growth Rating (51) in the Biotechnology industry is in the same range as KPTI (59). This means that XENE’s stock grew similarly to KPTI’s over the last 12 months.

XENE's P/E Growth Rating (5) in the Biotechnology industry is significantly better than the same rating for KPTI (100). This means that XENE’s stock grew significantly faster than KPTI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KPTIXENE
RSI
ODDS (%)
N/A
Bearish Trend 2 days ago
59%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
80%
Momentum
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
74%
MACD
ODDS (%)
Bearish Trend 2 days ago
89%
Bearish Trend 2 days ago
55%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
75%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
88%
Bearish Trend 2 days ago
73%
Advances
ODDS (%)
Bullish Trend 3 days ago
84%
Bullish Trend 4 days ago
72%
Declines
ODDS (%)
Bearish Trend 8 days ago
88%
Bearish Trend 8 days ago
70%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
74%
Bullish Trend 2 days ago
74%
Aroon
ODDS (%)
N/A
Bullish Trend 2 days ago
81%
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KPTI
Daily Signal:
Gain/Loss:
XENE
Daily Signal:
Gain/Loss:
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KPTI and

Correlation & Price change

A.I.dvisor indicates that over the last year, KPTI has been loosely correlated with XENE. These tickers have moved in lockstep 37% of the time. This A.I.-generated data suggests there is some statistical probability that if KPTI jumps, then XENE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KPTI
1D Price
Change %
KPTI100%
-1.61%
XENE - KPTI
37%
Loosely correlated
+0.91%
PGEN - KPTI
37%
Loosely correlated
-3.98%
MGNX - KPTI
36%
Loosely correlated
+8.84%
ARRY - KPTI
35%
Loosely correlated
-9.63%
OCGN - KPTI
34%
Loosely correlated
-7.46%
More

XENE and

Correlation & Price change

A.I.dvisor indicates that over the last year, XENE has been loosely correlated with NUVL. These tickers have moved in lockstep 60% of the time. This A.I.-generated data suggests there is some statistical probability that if XENE jumps, then NUVL could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To XENE
1D Price
Change %
XENE100%
+0.91%
NUVL - XENE
60%
Loosely correlated
-2.42%
IDYA - XENE
57%
Loosely correlated
-0.41%
NRIX - XENE
54%
Loosely correlated
+2.14%
DNLI - XENE
51%
Loosely correlated
-2.11%
IMVT - XENE
51%
Loosely correlated
-2.65%
More