KPTI
Price
$5.92
Change
+$0.46 (+8.42%)
Updated
Dec 4, 04:59 PM (EDT)
Capitalization
93.1M
Intraday BUY SELL Signals
SAVA
Price
$3.32
Change
+$0.22 (+7.10%)
Updated
Dec 4, 04:59 PM (EDT)
Capitalization
149.75M
89 days until earnings call
Intraday BUY SELL Signals
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KPTI vs SAVA

Header iconKPTI vs SAVA Comparison
Open Charts KPTI vs SAVABanner chart's image
Karyopharm Therapeutics
Price$5.92
Change+$0.46 (+8.42%)
Volume$608
Capitalization93.1M
Cassava Sciences
Price$3.32
Change+$0.22 (+7.10%)
Volume$3.32K
Capitalization149.75M
KPTI vs SAVA Comparison Chart in %
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VS
KPTI vs. SAVA commentary
Dec 05, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KPTI is a Hold and SAVA is a Hold.

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COMPARISON
Comparison
Dec 05, 2025
Stock price -- (KPTI: $5.46 vs. SAVA: $3.10)
Brand notoriety: KPTI and SAVA are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KPTI: 145% vs. SAVA: 37%
Market capitalization -- KPTI: $93.1M vs. SAVA: $149.75M
KPTI [@Biotechnology] is valued at $93.1M. SAVA’s [@Biotechnology] market capitalization is $149.75M. The market cap for tickers in the [@Biotechnology] industry ranges from $117.5B to $0. The average market capitalization across the [@Biotechnology] industry is $2.2B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KPTI’s FA Score shows that 1 FA rating(s) are green whileSAVA’s FA Score has 1 green FA rating(s).

  • KPTI’s FA Score: 1 green, 4 red.
  • SAVA’s FA Score: 1 green, 4 red.
According to our system of comparison, SAVA is a better buy in the long-term than KPTI.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KPTI’s TA Score shows that 3 TA indicator(s) are bullish while SAVA’s TA Score has 4 bullish TA indicator(s).

  • KPTI’s TA Score: 3 bullish, 4 bearish.
  • SAVA’s TA Score: 4 bullish, 6 bearish.
According to our system of comparison, KPTI is a better buy in the short-term than SAVA.

Price Growth

KPTI (@Biotechnology) experienced а -1.62% price change this week, while SAVA (@Biotechnology) price change was -8.55% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.21%. For the same industry, the average monthly price growth was +5.86%, and the average quarterly price growth was +56.03%.

Reported Earning Dates

SAVA is expected to report earnings on Mar 03, 2026.

Industries' Descriptions

@Biotechnology (+1.21% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SAVA($150M) has a higher market cap than KPTI($93.1M). SAVA YTD gains are higher at: 31.356 vs. KPTI (-46.178). KPTI has higher annual earnings (EBITDA): -78.44M vs. SAVA (-129.96M). SAVA has more cash in the bank: 112M vs. KPTI (51.7M). SAVA has less debt than KPTI: SAVA (0) vs KPTI (191M). KPTI has higher revenues than SAVA: KPTI (137M) vs SAVA (0).
KPTISAVAKPTI / SAVA
Capitalization93.1M150M62%
EBITDA-78.44M-129.96M60%
Gain YTD-46.17831.356-147%
P/E RatioN/AN/A-
Revenue137M0-
Total Cash51.7M112M46%
Total Debt191M0-
FUNDAMENTALS RATINGS
KPTI vs SAVA: Fundamental Ratings
KPTI
SAVA
OUTLOOK RATING
1..100
1722
VALUATION
overvalued / fair valued / undervalued
1..100
4
Undervalued
23
Undervalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10098
PRICE GROWTH RATING
1..100
6146
P/E GROWTH RATING
1..100
100100
SEASONALITY SCORE
1..100
n/a50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

KPTI's Valuation (4) in the Biotechnology industry is in the same range as SAVA (23) in the Pharmaceuticals Other industry. This means that KPTI’s stock grew similarly to SAVA’s over the last 12 months.

KPTI's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as SAVA (100) in the Pharmaceuticals Other industry. This means that KPTI’s stock grew similarly to SAVA’s over the last 12 months.

SAVA's SMR Rating (98) in the Pharmaceuticals Other industry is in the same range as KPTI (100) in the Biotechnology industry. This means that SAVA’s stock grew similarly to KPTI’s over the last 12 months.

SAVA's Price Growth Rating (46) in the Pharmaceuticals Other industry is in the same range as KPTI (61) in the Biotechnology industry. This means that SAVA’s stock grew similarly to KPTI’s over the last 12 months.

SAVA's P/E Growth Rating (100) in the Pharmaceuticals Other industry is in the same range as KPTI (100) in the Biotechnology industry. This means that SAVA’s stock grew similarly to KPTI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KPTISAVA
RSI
ODDS (%)
N/A
Bullish Trend 2 days ago
90%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
86%
Bearish Trend 2 days ago
90%
Momentum
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
80%
MACD
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
77%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
89%
Bearish Trend 2 days ago
87%
Advances
ODDS (%)
Bullish Trend 7 days ago
84%
Bullish Trend 9 days ago
84%
Declines
ODDS (%)
Bearish Trend 10 days ago
88%
Bearish Trend 15 days ago
87%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
90%
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
N/A
Bearish Trend 2 days ago
83%
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KPTI
Daily Signal:
Gain/Loss:
SAVA
Daily Signal:
Gain/Loss:
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KPTI and

Correlation & Price change

A.I.dvisor indicates that over the last year, KPTI has been loosely correlated with PGEN. These tickers have moved in lockstep 36% of the time. This A.I.-generated data suggests there is some statistical probability that if KPTI jumps, then PGEN could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KPTI
1D Price
Change %
KPTI100%
+1.87%
PGEN - KPTI
36%
Loosely correlated
+2.59%
XENE - KPTI
36%
Loosely correlated
+3.29%
SAVA - KPTI
36%
Loosely correlated
+7.27%
ARRY - KPTI
35%
Loosely correlated
+4.28%
MGNX - KPTI
35%
Loosely correlated
-1.41%
More

SAVA and

Correlation & Price change

A.I.dvisor indicates that over the last year, SAVA has been loosely correlated with IMNM. These tickers have moved in lockstep 38% of the time. This A.I.-generated data suggests there is some statistical probability that if SAVA jumps, then IMNM could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SAVA
1D Price
Change %
SAVA100%
+7.27%
IMNM - SAVA
38%
Loosely correlated
+13.34%
RXRX - SAVA
36%
Loosely correlated
+7.87%
IPSC - SAVA
36%
Loosely correlated
-3.63%
CRBU - SAVA
36%
Loosely correlated
+5.68%
ABCL - SAVA
35%
Loosely correlated
+0.87%
More