KPTI
Price
$7.47
Change
+$0.03 (+0.40%)
Updated
Dec 24 closing price
Capitalization
127.37M
Intraday BUY SELL Signals
PRQR
Price
$2.17
Change
-$0.04 (-1.81%)
Updated
Dec 24 closing price
Capitalization
228.6M
56 days until earnings call
Intraday BUY SELL Signals
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KPTI vs PRQR

Header iconKPTI vs PRQR Comparison
Open Charts KPTI vs PRQRBanner chart's image
Karyopharm Therapeutics
Price$7.47
Change+$0.03 (+0.40%)
Volume$77.16K
Capitalization127.37M
ProQR Therapeutics
Price$2.17
Change-$0.04 (-1.81%)
Volume$144.81K
Capitalization228.6M
KPTI vs PRQR Comparison Chart in %
KPTI
Daily Signal:
Gain/Loss:
PRQR
Daily Signal:
Gain/Loss:
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KPTI vs. PRQR commentary
Dec 25, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KPTI is a Buy and PRQR is a Hold.

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COMPARISON
Comparison
Dec 25, 2025
Stock price -- (KPTI: $7.47 vs. PRQR: $2.17)
Brand notoriety: KPTI and PRQR are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KPTI: 47% vs. PRQR: 29%
Market capitalization -- KPTI: $127.37M vs. PRQR: $228.6M
KPTI [@Biotechnology] is valued at $127.37M. PRQR’s [@Biotechnology] market capitalization is $228.6M. The market cap for tickers in the [@Biotechnology] industry ranges from $117.47B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KPTI’s FA Score shows that 1 FA rating(s) are green whilePRQR’s FA Score has 1 green FA rating(s).

  • KPTI’s FA Score: 1 green, 4 red.
  • PRQR’s FA Score: 1 green, 4 red.
According to our system of comparison, KPTI is a better buy in the long-term than PRQR.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KPTI’s TA Score shows that 6 TA indicator(s) are bullish while PRQR’s TA Score has 4 bullish TA indicator(s).

  • KPTI’s TA Score: 6 bullish, 4 bearish.
  • PRQR’s TA Score: 4 bullish, 5 bearish.
According to our system of comparison, KPTI is a better buy in the short-term than PRQR.

Price Growth

KPTI (@Biotechnology) experienced а +24.09% price change this week, while PRQR (@Biotechnology) price change was +1.40% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.88%. For the same industry, the average monthly price growth was +4.46%, and the average quarterly price growth was +55.39%.

Reported Earning Dates

PRQR is expected to report earnings on Feb 19, 2026.

Industries' Descriptions

@Biotechnology (+2.88% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PRQR($229M) has a higher market cap than KPTI($127M). PRQR YTD gains are higher at: -18.113 vs. KPTI (-26.364). PRQR has higher annual earnings (EBITDA): -38.15M vs. KPTI (-79.83M). PRQR has more cash in the bank: 107M vs. KPTI (45.9M). PRQR has less debt than KPTI: PRQR (16.5M) vs KPTI (196M). KPTI has higher revenues than PRQR: KPTI (143M) vs PRQR (15.5M).
KPTIPRQRKPTI / PRQR
Capitalization127M229M55%
EBITDA-79.83M-38.15M209%
Gain YTD-26.364-18.113146%
P/E RatioN/AN/A-
Revenue143M15.5M923%
Total Cash45.9M107M43%
Total Debt196M16.5M1,188%
FUNDAMENTALS RATINGS
KPTI vs PRQR: Fundamental Ratings
KPTI
PRQR
OUTLOOK RATING
1..100
2677
VALUATION
overvalued / fair valued / undervalued
1..100
4
Undervalued
30
Undervalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10099
PRICE GROWTH RATING
1..100
4153
P/E GROWTH RATING
1..100
100100
SEASONALITY SCORE
1..100
50n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

KPTI's Valuation (4) in the Biotechnology industry is in the same range as PRQR (30). This means that KPTI’s stock grew similarly to PRQR’s over the last 12 months.

KPTI's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as PRQR (100). This means that KPTI’s stock grew similarly to PRQR’s over the last 12 months.

PRQR's SMR Rating (99) in the Biotechnology industry is in the same range as KPTI (100). This means that PRQR’s stock grew similarly to KPTI’s over the last 12 months.

KPTI's Price Growth Rating (41) in the Biotechnology industry is in the same range as PRQR (53). This means that KPTI’s stock grew similarly to PRQR’s over the last 12 months.

KPTI's P/E Growth Rating (100) in the Biotechnology industry is in the same range as PRQR (100). This means that KPTI’s stock grew similarly to PRQR’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KPTIPRQR
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 3 days ago
83%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
83%
Momentum
ODDS (%)
Bullish Trend 2 days ago
77%
Bearish Trend 2 days ago
85%
MACD
ODDS (%)
Bullish Trend 2 days ago
80%
Bullish Trend 2 days ago
76%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 2 days ago
81%
Advances
ODDS (%)
Bullish Trend 2 days ago
84%
Bullish Trend 17 days ago
84%
Declines
ODDS (%)
Bearish Trend 9 days ago
88%
Bearish Trend 8 days ago
84%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
86%
Aroon
ODDS (%)
Bullish Trend 2 days ago
63%
Bearish Trend 2 days ago
84%
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KPTI
Daily Signal:
Gain/Loss:
PRQR
Daily Signal:
Gain/Loss:
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KPTI and

Correlation & Price change

A.I.dvisor indicates that over the last year, KPTI has been loosely correlated with XENE. These tickers have moved in lockstep 37% of the time. This A.I.-generated data suggests there is some statistical probability that if KPTI jumps, then XENE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KPTI
1D Price
Change %
KPTI100%
+0.40%
XENE - KPTI
37%
Loosely correlated
+1.06%
PGEN - KPTI
36%
Loosely correlated
+2.95%
ARRY - KPTI
35%
Loosely correlated
+2.10%
PRQR - KPTI
34%
Loosely correlated
-1.81%
MGNX - KPTI
33%
Loosely correlated
+1.25%
More

PRQR and

Correlation & Price change

A.I.dvisor indicates that over the last year, PRQR has been loosely correlated with BEAM. These tickers have moved in lockstep 49% of the time. This A.I.-generated data suggests there is some statistical probability that if PRQR jumps, then BEAM could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PRQR
1D Price
Change %
PRQR100%
-1.81%
BEAM - PRQR
49%
Loosely correlated
+1.33%
RGNX - PRQR
48%
Loosely correlated
+0.77%
ETHZ - PRQR
44%
Loosely correlated
-4.11%
DNLI - PRQR
44%
Loosely correlated
+1.07%
SYRE - PRQR
43%
Loosely correlated
-0.54%
More