KPTI
Price
$7.44
Change
-$0.03 (-0.40%)
Updated
Dec 26 closing price
Capitalization
126.86M
Intraday BUY SELL Signals
MGNX
Price
$1.61
Change
-$0.01 (-0.62%)
Updated
Dec 26 closing price
Capitalization
101.85M
53 days until earnings call
Intraday BUY SELL Signals
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KPTI vs MGNX

Header iconKPTI vs MGNX Comparison
Open Charts KPTI vs MGNXBanner chart's image
Karyopharm Therapeutics
Price$7.44
Change-$0.03 (-0.40%)
Volume$106.3K
Capitalization126.86M
MacroGenics
Price$1.61
Change-$0.01 (-0.62%)
Volume$444.25K
Capitalization101.85M
KPTI vs MGNX Comparison Chart in %
KPTI
Daily Signal:
Gain/Loss:
MGNX
Daily Signal:
Gain/Loss:
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KPTI vs. MGNX commentary
Dec 28, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is KPTI is a Buy and MGNX is a StrongBuy.

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COMPARISON
Comparison
Dec 28, 2025
Stock price -- (KPTI: $7.44 vs. MGNX: $1.61)
Brand notoriety: KPTI and MGNX are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: KPTI: 65% vs. MGNX: 31%
Market capitalization -- KPTI: $126.86M vs. MGNX: $101.85M
KPTI [@Biotechnology] is valued at $126.86M. MGNX’s [@Biotechnology] market capitalization is $101.85M. The market cap for tickers in the [@Biotechnology] industry ranges from $117.45B to $0. The average market capitalization across the [@Biotechnology] industry is $2.21B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

KPTI’s FA Score shows that 1 FA rating(s) are green whileMGNX’s FA Score has 0 green FA rating(s).

  • KPTI’s FA Score: 1 green, 4 red.
  • MGNX’s FA Score: 0 green, 5 red.
According to our system of comparison, KPTI is a better buy in the long-term than MGNX.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

KPTI’s TA Score shows that 6 TA indicator(s) are bullish while MGNX’s TA Score has 4 bullish TA indicator(s).

  • KPTI’s TA Score: 6 bullish, 4 bearish.
  • MGNX’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, KPTI is a better buy in the short-term than MGNX.

Price Growth

KPTI (@Biotechnology) experienced а +7.20% price change this week, while MGNX (@Biotechnology) price change was +7.33% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.36%. For the same industry, the average monthly price growth was +0.27%, and the average quarterly price growth was +54.56%.

Reported Earning Dates

MGNX is expected to report earnings on Feb 19, 2026.

Industries' Descriptions

@Biotechnology (+0.36% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
KPTI($127M) has a higher market cap than MGNX($102M). KPTI YTD gains are higher at: -26.660 vs. MGNX (-50.462). MGNX has higher annual earnings (EBITDA): -63.11M vs. KPTI (-79.83M). MGNX has more cash in the bank: 146M vs. KPTI (45.9M). MGNX has less debt than KPTI: MGNX (37M) vs KPTI (196M). KPTI has higher revenues than MGNX: KPTI (143M) vs MGNX (126M).
KPTIMGNXKPTI / MGNX
Capitalization127M102M125%
EBITDA-79.83M-63.11M127%
Gain YTD-26.660-50.46253%
P/E RatioN/AN/A-
Revenue143M126M113%
Total Cash45.9M146M31%
Total Debt196M37M530%
FUNDAMENTALS RATINGS
KPTI vs MGNX: Fundamental Ratings
KPTI
MGNX
OUTLOOK RATING
1..100
2662
VALUATION
overvalued / fair valued / undervalued
1..100
4
Undervalued
81
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10098
PRICE GROWTH RATING
1..100
3951
P/E GROWTH RATING
1..100
10094
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

KPTI's Valuation (4) in the Biotechnology industry is significantly better than the same rating for MGNX (81). This means that KPTI’s stock grew significantly faster than MGNX’s over the last 12 months.

KPTI's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as MGNX (100). This means that KPTI’s stock grew similarly to MGNX’s over the last 12 months.

MGNX's SMR Rating (98) in the Biotechnology industry is in the same range as KPTI (100). This means that MGNX’s stock grew similarly to KPTI’s over the last 12 months.

KPTI's Price Growth Rating (39) in the Biotechnology industry is in the same range as MGNX (51). This means that KPTI’s stock grew similarly to MGNX’s over the last 12 months.

MGNX's P/E Growth Rating (94) in the Biotechnology industry is in the same range as KPTI (100). This means that MGNX’s stock grew similarly to KPTI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
KPTIMGNX
RSI
ODDS (%)
Bearish Trend 2 days ago
87%
N/A
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
90%
Momentum
ODDS (%)
Bullish Trend 2 days ago
79%
Bullish Trend 2 days ago
85%
MACD
ODDS (%)
Bullish Trend 2 days ago
84%
Bullish Trend 2 days ago
88%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
84%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 2 days ago
85%
Advances
ODDS (%)
Bullish Trend 4 days ago
84%
Bullish Trend 4 days ago
83%
Declines
ODDS (%)
Bearish Trend 11 days ago
88%
Bearish Trend 9 days ago
87%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
85%
Aroon
ODDS (%)
Bullish Trend 2 days ago
66%
Bearish Trend 2 days ago
90%
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KPTI
Daily Signal:
Gain/Loss:
MGNX
Daily Signal:
Gain/Loss:
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KPTI and

Correlation & Price change

A.I.dvisor indicates that over the last year, KPTI has been loosely correlated with XENE. These tickers have moved in lockstep 37% of the time. This A.I.-generated data suggests there is some statistical probability that if KPTI jumps, then XENE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To KPTI
1D Price
Change %
KPTI100%
-0.40%
XENE - KPTI
37%
Loosely correlated
-0.38%
PGEN - KPTI
36%
Loosely correlated
-0.72%
ARRY - KPTI
35%
Loosely correlated
+0.39%
PRQR - KPTI
34%
Loosely correlated
N/A
MGNX - KPTI
33%
Loosely correlated
-0.62%
More

MGNX and

Correlation & Price change

A.I.dvisor indicates that over the last year, MGNX has been loosely correlated with IDYA. These tickers have moved in lockstep 47% of the time. This A.I.-generated data suggests there is some statistical probability that if MGNX jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To MGNX
1D Price
Change %
MGNX100%
-0.62%
IDYA - MGNX
47%
Loosely correlated
-1.35%
RGNX - MGNX
47%
Loosely correlated
-2.07%
CRBU - MGNX
47%
Loosely correlated
-1.16%
BEAM - MGNX
46%
Loosely correlated
-0.57%
FATE - MGNX
45%
Loosely correlated
-0.99%
More