ITOS
Price
$10.15
Change
+$0.02 (+0.20%)
Updated
Aug 28 closing price
Capitalization
448.68M
60 days until earnings call
SPRO
Price
$2.15
Change
+$0.01 (+0.47%)
Updated
Sep 5 closing price
Capitalization
120.99M
72 days until earnings call
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ITOS vs SPRO

Header iconITOS vs SPRO Comparison
Open Charts ITOS vs SPROBanner chart's image
iTeos Therapeutics
Price$10.15
Change+$0.02 (+0.20%)
Volume$11.01M
Capitalization448.68M
Spero Therapeutics
Price$2.15
Change+$0.01 (+0.47%)
Volume$175.51K
Capitalization120.99M
ITOS vs SPRO Comparison Chart in %
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ITOS
Daily Signalchanged days ago
Gain/Loss if bought
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SPRO
Daily Signalchanged days ago
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ITOS vs. SPRO commentary
Sep 06, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is ITOS is a StrongBuy and SPRO is a Buy.

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COMPARISON
Comparison
Sep 06, 2025
Stock price -- (ITOS: $10.15 vs. SPRO: $2.15)
Brand notoriety: ITOS and SPRO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: ITOS: 430% vs. SPRO: 25%
Market capitalization -- ITOS: $448.68M vs. SPRO: $120.99M
ITOS [@Biotechnology] is valued at $448.68M. SPRO’s [@Biotechnology] market capitalization is $120.99M. The market cap for tickers in the [@Biotechnology] industry ranges from $101.56B to $0. The average market capitalization across the [@Biotechnology] industry is $1.91B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

ITOS’s FA Score shows that 1 FA rating(s) are green whileSPRO’s FA Score has 1 green FA rating(s).

  • ITOS’s FA Score: 1 green, 4 red.
  • SPRO’s FA Score: 1 green, 4 red.
According to our system of comparison, SPRO is a better buy in the long-term than ITOS.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

ITOS’s TA Score shows that 5 TA indicator(s) are bullish while SPRO’s TA Score has 5 bullish TA indicator(s).

  • ITOS’s TA Score: 5 bullish, 3 bearish.
  • SPRO’s TA Score: 5 bullish, 3 bearish.
According to our system of comparison, both ITOS and SPRO are a good buy in the short-term.

Price Growth

ITOS (@Biotechnology) experienced а 0.00% price change this week, while SPRO (@Biotechnology) price change was +3.86% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.52%. For the same industry, the average monthly price growth was +14.52%, and the average quarterly price growth was +33.01%.

Reported Earning Dates

ITOS is expected to report earnings on Nov 05, 2025.

SPRO is expected to report earnings on Nov 17, 2025.

Industries' Descriptions

@Biotechnology (+2.52% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
ITOS($449M) has a higher market cap than SPRO($121M). SPRO YTD gains are higher at: 108.738 vs. ITOS (32.161). SPRO has higher annual earnings (EBITDA): -56.36M vs. ITOS (-200.45M). ITOS has more cash in the bank: 515M vs. SPRO (31.2M). SPRO has less debt than ITOS: SPRO (3.62M) vs ITOS (5.13M). SPRO has higher revenues than ITOS: SPRO (34.1M) vs ITOS (0).
ITOSSPROITOS / SPRO
Capitalization449M121M371%
EBITDA-200.45M-56.36M356%
Gain YTD32.161108.73830%
P/E RatioN/A10.75-
Revenue034.1M-
Total Cash515M31.2M1,651%
Total Debt5.13M3.62M142%
FUNDAMENTALS RATINGS
SPRO: Fundamental Ratings
SPRO
OUTLOOK RATING
1..100
6
VALUATION
overvalued / fair valued / undervalued
1..100
50
Fair valued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
99
PRICE GROWTH RATING
1..100
38
P/E GROWTH RATING
1..100
7
SEASONALITY SCORE
1..100
85

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
ITOSSPRO
RSI
ODDS (%)
N/A
Bullish Trend 1 day ago
66%
Stochastic
ODDS (%)
Bullish Trend 1 day ago
73%
Bearish Trend 1 day ago
81%
Momentum
ODDS (%)
Bearish Trend 1 day ago
72%
Bullish Trend 1 day ago
77%
MACD
ODDS (%)
N/A
Bullish Trend 1 day ago
74%
TrendWeek
ODDS (%)
Bullish Trend 1 day ago
73%
Bullish Trend 1 day ago
74%
TrendMonth
ODDS (%)
Bullish Trend 1 day ago
70%
Bullish Trend 1 day ago
76%
Advances
ODDS (%)
Bullish Trend 18 days ago
70%
Bullish Trend 1 day ago
71%
Declines
ODDS (%)
Bearish Trend 13 days ago
77%
Bearish Trend 18 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 1 day ago
90%
Bullish Trend 1 day ago
84%
Aroon
ODDS (%)
Bullish Trend 1 day ago
71%
Bearish Trend 1 day ago
89%
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ITOS
Daily Signalchanged days ago
Gain/Loss if bought
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SPRO
Daily Signalchanged days ago
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ITOS and

Correlation & Price change

A.I.dvisor indicates that over the last year, ITOS has been loosely correlated with BMRN. These tickers have moved in lockstep 50% of the time. This A.I.-generated data suggests there is some statistical probability that if ITOS jumps, then BMRN could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ITOS
1D Price
Change %
ITOS100%
N/A
BMRN - ITOS
50%
Loosely correlated
+1.80%
IBO - ITOS
45%
Loosely correlated
+3.81%
CRBP - ITOS
44%
Loosely correlated
-1.60%
OCUL - ITOS
40%
Loosely correlated
+7.09%
IMNM - ITOS
39%
Loosely correlated
+7.35%
More

SPRO and

Correlation & Price change

A.I.dvisor indicates that over the last year, SPRO has been loosely correlated with ASBP. These tickers have moved in lockstep 62% of the time. This A.I.-generated data suggests there is some statistical probability that if SPRO jumps, then ASBP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SPRO
1D Price
Change %
SPRO100%
+0.47%
ASBP - SPRO
62%
Loosely correlated
-6.04%
CLGN - SPRO
42%
Loosely correlated
+4.31%
IMNN - SPRO
41%
Loosely correlated
+0.61%
ITOS - SPRO
35%
Loosely correlated
N/A
XENE - SPRO
32%
Poorly correlated
+1.48%
More