IONS
Price
$81.84
Change
+$0.53 (+0.65%)
Updated
Dec 3 closing price
Capitalization
13.26B
83 days until earnings call
Intraday BUY SELL Signals
MNKD
Price
$5.59
Change
-$0.00 (-0.00%)
Updated
Dec 3 closing price
Capitalization
1.72B
89 days until earnings call
Intraday BUY SELL Signals
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IONS vs MNKD

Header iconIONS vs MNKD Comparison
Open Charts IONS vs MNKDBanner chart's image
Ionis Pharmaceuticals
Price$81.84
Change+$0.53 (+0.65%)
Volume$2.53M
Capitalization13.26B
MannKind
Price$5.59
Change-$0.00 (-0.00%)
Volume$3.4M
Capitalization1.72B
IONS vs MNKD Comparison Chart in %
IONS
Daily Signal:
Gain/Loss:
MNKD
Daily Signal:
Gain/Loss:
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IONS vs. MNKD commentary
Dec 04, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is IONS is a Hold and MNKD is a Hold.

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COMPARISON
Comparison
Dec 04, 2025
Stock price -- (IONS: $81.35 vs. MNKD: $5.59)
Brand notoriety: IONS and MNKD are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: IONS: 51% vs. MNKD: 36%
Market capitalization -- IONS: $13.26B vs. MNKD: $1.72B
IONS [@Biotechnology] is valued at $13.26B. MNKD’s [@Biotechnology] market capitalization is $1.72B. The market cap for tickers in the [@Biotechnology] industry ranges from $117.5B to $0. The average market capitalization across the [@Biotechnology] industry is $2.19B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

IONS’s FA Score shows that 0 FA rating(s) are green whileMNKD’s FA Score has 0 green FA rating(s).

  • IONS’s FA Score: 0 green, 5 red.
  • MNKD’s FA Score: 0 green, 5 red.
According to our system of comparison, IONS is a better buy in the long-term than MNKD.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

IONS’s TA Score shows that 4 TA indicator(s) are bullish while MNKD’s TA Score has 4 bullish TA indicator(s).

  • IONS’s TA Score: 4 bullish, 4 bearish.
  • MNKD’s TA Score: 4 bullish, 6 bearish.
According to our system of comparison, IONS is a better buy in the short-term than MNKD.

Price Growth

IONS (@Biotechnology) experienced а +0.52% price change this week, while MNKD (@Biotechnology) price change was +4.38% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.32%. For the same industry, the average monthly price growth was +1.23%, and the average quarterly price growth was +54.93%.

Reported Earning Dates

IONS is expected to report earnings on Feb 25, 2026.

MNKD is expected to report earnings on Mar 03, 2026.

Industries' Descriptions

@Biotechnology (+0.32% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
IONS($13.3B) has a higher market cap than MNKD($1.72B). IONS YTD gains are higher at: 132.695 vs. MNKD (-12.986). MNKD has higher annual earnings (EBITDA): 79.1M vs. IONS (-170.69M). IONS has more cash in the bank: 2.29B vs. MNKD (179M). MNKD has less debt than IONS: MNKD (46.8M) vs IONS (1.42B). IONS has higher revenues than MNKD: IONS (944M) vs MNKD (302M).
IONSMNKDIONS / MNKD
Capitalization13.3B1.72B775%
EBITDA-170.69M79.1M-216%
Gain YTD132.695-12.986-1,022%
P/E RatioN/A55.90-
Revenue944M302M313%
Total Cash2.29B179M1,279%
Total Debt1.42B46.8M3,034%
FUNDAMENTALS RATINGS
IONS vs MNKD: Fundamental Ratings
IONS
MNKD
OUTLOOK RATING
1..100
5050
VALUATION
overvalued / fair valued / undervalued
1..100
100
Overvalued
81
Overvalued
PROFIT vs RISK RATING
1..100
4751
SMR RATING
1..100
97100
PRICE GROWTH RATING
1..100
3550
P/E GROWTH RATING
1..100
5586
SEASONALITY SCORE
1..100
5085

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

MNKD's Valuation (81) in the Biotechnology industry is in the same range as IONS (100). This means that MNKD’s stock grew similarly to IONS’s over the last 12 months.

IONS's Profit vs Risk Rating (47) in the Biotechnology industry is in the same range as MNKD (51). This means that IONS’s stock grew similarly to MNKD’s over the last 12 months.

IONS's SMR Rating (97) in the Biotechnology industry is in the same range as MNKD (100). This means that IONS’s stock grew similarly to MNKD’s over the last 12 months.

IONS's Price Growth Rating (35) in the Biotechnology industry is in the same range as MNKD (50). This means that IONS’s stock grew similarly to MNKD’s over the last 12 months.

IONS's P/E Growth Rating (55) in the Biotechnology industry is in the same range as MNKD (86). This means that IONS’s stock grew similarly to MNKD’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
IONSMNKD
RSI
ODDS (%)
Bearish Trend 7 days ago
70%
Bearish Trend 7 days ago
86%
Stochastic
ODDS (%)
Bearish Trend 7 days ago
71%
Bearish Trend 7 days ago
79%
Momentum
ODDS (%)
Bullish Trend 7 days ago
74%
Bullish Trend 7 days ago
76%
MACD
ODDS (%)
Bullish Trend 7 days ago
71%
Bullish Trend 7 days ago
85%
TrendWeek
ODDS (%)
Bullish Trend 7 days ago
71%
Bullish Trend 7 days ago
80%
TrendMonth
ODDS (%)
Bullish Trend 7 days ago
73%
Bullish Trend 7 days ago
76%
Advances
ODDS (%)
Bullish Trend 7 days ago
67%
Bullish Trend 9 days ago
80%
Declines
ODDS (%)
Bearish Trend 15 days ago
66%
Bearish Trend 15 days ago
81%
BollingerBands
ODDS (%)
Bearish Trend 7 days ago
71%
Bearish Trend 7 days ago
90%
Aroon
ODDS (%)
Bullish Trend 7 days ago
70%
Bullish Trend 7 days ago
77%
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IONS
Daily Signal:
Gain/Loss:
MNKD
Daily Signal:
Gain/Loss:
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IONS and

Correlation & Price change

A.I.dvisor indicates that over the last year, IONS has been loosely correlated with CYTK. These tickers have moved in lockstep 62% of the time. This A.I.-generated data suggests there is some statistical probability that if IONS jumps, then CYTK could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To IONS
1D Price
Change %
IONS100%
-0.78%
CYTK - IONS
62%
Loosely correlated
-3.79%
MLYS - IONS
49%
Loosely correlated
-3.93%
MNKD - IONS
48%
Loosely correlated
+3.04%
RARE - IONS
46%
Loosely correlated
+0.28%
IDYA - IONS
46%
Loosely correlated
-1.75%
More

MNKD and

Correlation & Price change

A.I.dvisor indicates that over the last year, MNKD has been loosely correlated with IONS. These tickers have moved in lockstep 48% of the time. This A.I.-generated data suggests there is some statistical probability that if MNKD jumps, then IONS could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To MNKD
1D Price
Change %
MNKD100%
+3.04%
IONS - MNKD
48%
Loosely correlated
-0.78%
VCYT - MNKD
44%
Loosely correlated
-0.43%
INSM - MNKD
40%
Loosely correlated
-2.19%
DAWN - MNKD
39%
Loosely correlated
-3.87%
CYTK - MNKD
37%
Loosely correlated
-3.79%
More