IONS
Price
$64.09
Change
+$1.12 (+1.78%)
Updated
Sep 26 closing price
Capitalization
10.22B
33 days until earnings call
MLYS
Price
$39.99
Change
+$1.48 (+3.84%)
Updated
Sep 26 closing price
Capitalization
3.1B
45 days until earnings call
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IONS vs MLYS

Header iconIONS vs MLYS Comparison
Open Charts IONS vs MLYSBanner chart's image
Ionis Pharmaceuticals
Price$64.09
Change+$1.12 (+1.78%)
Volume$1.52M
Capitalization10.22B
Mineralys Therapeutics
Price$39.99
Change+$1.48 (+3.84%)
Volume$1.64M
Capitalization3.1B
IONS vs MLYS Comparison Chart in %
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IONS
Daily Signalchanged days ago
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MLYS
Daily Signalchanged days ago
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IONS vs. MLYS commentary
Sep 27, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is IONS is a StrongBuy and MLYS is a StrongBuy.

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COMPARISON
Comparison
Sep 27, 2025
Stock price -- (IONS: $64.09 vs. MLYS: $39.98)
Brand notoriety: IONS and MLYS are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: IONS: 29% vs. MLYS: 54%
Market capitalization -- IONS: $10.04B vs. MLYS: $2.99B
IONS [@Biotechnology] is valued at $10.04B. MLYS’s [@Biotechnology] market capitalization is $2.99B. The market cap for tickers in the [@Biotechnology] industry ranges from $97.91B to $0. The average market capitalization across the [@Biotechnology] industry is $1.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

IONS’s FA Score shows that 0 FA rating(s) are green whileMLYS’s FA Score has 0 green FA rating(s).

  • IONS’s FA Score: 0 green, 5 red.
  • MLYS’s FA Score: 0 green, 5 red.
According to our system of comparison, both IONS and MLYS are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

IONS’s TA Score shows that 2 TA indicator(s) are bullish while MLYS’s TA Score has 4 bullish TA indicator(s).

  • IONS’s TA Score: 2 bullish, 6 bearish.
  • MLYS’s TA Score: 4 bullish, 5 bearish.
According to our system of comparison, MLYS is a better buy in the short-term than IONS.

Price Growth

IONS (@Biotechnology) experienced а +5.05% price change this week, while MLYS (@Biotechnology) price change was +1.81% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.14%. For the same industry, the average monthly price growth was +9.25%, and the average quarterly price growth was +54.64%.

Reported Earning Dates

IONS is expected to report earnings on Oct 30, 2025.

MLYS is expected to report earnings on Nov 11, 2025.

Industries' Descriptions

@Biotechnology (+4.14% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
IONS($10.2B) has a higher market cap than MLYS($3.1B). MLYS YTD gains are higher at: 224.858 vs. IONS (83.324). IONS has higher annual earnings (EBITDA): -170.69M vs. MLYS (-203.01M). IONS has more cash in the bank: 2.29B vs. MLYS (325M). IONS has higher revenues than MLYS: IONS (944M) vs MLYS (0).
IONSMLYSIONS / MLYS
Capitalization10.2B3.1B329%
EBITDA-170.69M-203.01M84%
Gain YTD83.324224.85837%
P/E RatioN/AN/A-
Revenue944M0-
Total Cash2.29B325M705%
Total Debt1.42BN/A-
FUNDAMENTALS RATINGS
IONS: Fundamental Ratings
IONS
OUTLOOK RATING
1..100
86
VALUATION
overvalued / fair valued / undervalued
1..100
95
Overvalued
PROFIT vs RISK RATING
1..100
78
SMR RATING
1..100
98
PRICE GROWTH RATING
1..100
36
P/E GROWTH RATING
1..100
60
SEASONALITY SCORE
1..100
50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
IONSMLYS
RSI
ODDS (%)
Bearish Trend 2 days ago
56%
Bearish Trend 2 days ago
71%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
64%
Bearish Trend 2 days ago
89%
Momentum
ODDS (%)
Bearish Trend 2 days ago
66%
Bullish Trend 2 days ago
81%
MACD
ODDS (%)
Bearish Trend 2 days ago
70%
Bearish Trend 2 days ago
86%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
70%
Bearish Trend 2 days ago
82%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
72%
Bullish Trend 2 days ago
83%
Advances
ODDS (%)
Bullish Trend 3 days ago
65%
Bullish Trend 18 days ago
87%
Declines
ODDS (%)
Bearish Trend 12 days ago
67%
Bearish Trend 4 days ago
85%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
73%
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
Bullish Trend 2 days ago
67%
Bullish Trend 2 days ago
84%
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IONS
Daily Signalchanged days ago
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MLYS
Daily Signalchanged days ago
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IONS and

Correlation & Price change

A.I.dvisor indicates that over the last year, IONS has been loosely correlated with CYTK. These tickers have moved in lockstep 63% of the time. This A.I.-generated data suggests there is some statistical probability that if IONS jumps, then CYTK could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To IONS
1D Price
Change %
IONS100%
+1.78%
CYTK - IONS
63%
Loosely correlated
+5.37%
MLYS - IONS
52%
Loosely correlated
+3.84%
IDYA - IONS
48%
Loosely correlated
+4.44%
CRNX - IONS
48%
Loosely correlated
+27.92%
MNKD - IONS
48%
Loosely correlated
+3.75%
More

MLYS and

Correlation & Price change

A.I.dvisor indicates that over the last year, MLYS has been loosely correlated with CYTK. These tickers have moved in lockstep 54% of the time. This A.I.-generated data suggests there is some statistical probability that if MLYS jumps, then CYTK could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To MLYS
1D Price
Change %
MLYS100%
+3.84%
CYTK - MLYS
54%
Loosely correlated
+5.37%
IONS - MLYS
52%
Loosely correlated
+1.78%
BIESF - MLYS
45%
Loosely correlated
N/A
NEVPF - MLYS
43%
Loosely correlated
N/A
PTGX - MLYS
39%
Loosely correlated
+4.20%
More