IONS
Price
$80.65
Change
+$0.32 (+0.40%)
Updated
Dec 24 closing price
Capitalization
13.06B
61 days until earnings call
Intraday BUY SELL Signals
MLYS
Price
$37.43
Change
+$0.08 (+0.21%)
Updated
Dec 24 closing price
Capitalization
2.96B
82 days until earnings call
Intraday BUY SELL Signals
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IONS vs MLYS

Header iconIONS vs MLYS Comparison
Open Charts IONS vs MLYSBanner chart's image
Ionis Pharmaceuticals
Price$80.65
Change+$0.32 (+0.40%)
Volume$480.23K
Capitalization13.06B
Mineralys Therapeutics
Price$37.43
Change+$0.08 (+0.21%)
Volume$665.23K
Capitalization2.96B
IONS vs MLYS Comparison Chart in %
IONS
Daily Signal:
Gain/Loss:
MLYS
Daily Signal:
Gain/Loss:
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VS
IONS vs. MLYS commentary
Dec 26, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is IONS is a Hold and MLYS is a Hold.

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COMPARISON
Comparison
Dec 26, 2025
Stock price -- (IONS: $80.65 vs. MLYS: $37.43)
Brand notoriety: IONS and MLYS are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: IONS: 19% vs. MLYS: 43%
Market capitalization -- IONS: $13.06B vs. MLYS: $2.96B
IONS [@Biotechnology] is valued at $13.06B. MLYS’s [@Biotechnology] market capitalization is $2.96B. The market cap for tickers in the [@Biotechnology] industry ranges from $117.47B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

IONS’s FA Score shows that 0 FA rating(s) are green whileMLYS’s FA Score has 0 green FA rating(s).

  • IONS’s FA Score: 0 green, 5 red.
  • MLYS’s FA Score: 0 green, 5 red.
According to our system of comparison, MLYS is a better buy in the long-term than IONS.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

IONS’s TA Score shows that 3 TA indicator(s) are bullish while MLYS’s TA Score has 5 bullish TA indicator(s).

  • IONS’s TA Score: 3 bullish, 5 bearish.
  • MLYS’s TA Score: 5 bullish, 3 bearish.
According to our system of comparison, MLYS is a better buy in the short-term than IONS.

Price Growth

IONS (@Biotechnology) experienced а +4.63% price change this week, while MLYS (@Biotechnology) price change was +1.11% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.88%. For the same industry, the average monthly price growth was +4.46%, and the average quarterly price growth was +55.39%.

Reported Earning Dates

IONS is expected to report earnings on Feb 25, 2026.

MLYS is expected to report earnings on Mar 18, 2026.

Industries' Descriptions

@Biotechnology (+2.88% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
IONS($13.1B) has a higher market cap than MLYS($2.96B). MLYS YTD gains are higher at: 204.062 vs. IONS (130.692). IONS has higher annual earnings (EBITDA): -153.61M vs. MLYS (-184.03M). IONS has more cash in the bank: 2.24B vs. MLYS (594M). IONS has higher revenues than MLYS: IONS (967M) vs MLYS (0).
IONSMLYSIONS / MLYS
Capitalization13.1B2.96B442%
EBITDA-153.61M-184.03M83%
Gain YTD130.692204.06264%
P/E RatioN/AN/A-
Revenue967M0-
Total Cash2.24B594M377%
Total Debt1.49BN/A-
FUNDAMENTALS RATINGS
IONS: Fundamental Ratings
IONS
OUTLOOK RATING
1..100
75
VALUATION
overvalued / fair valued / undervalued
1..100
99
Overvalued
PROFIT vs RISK RATING
1..100
53
SMR RATING
1..100
97
PRICE GROWTH RATING
1..100
37
P/E GROWTH RATING
1..100
64
SEASONALITY SCORE
1..100
50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
IONSMLYS
RSI
ODDS (%)
Bearish Trend 2 days ago
73%
Bullish Trend 2 days ago
78%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
78%
Bullish Trend 2 days ago
78%
Momentum
ODDS (%)
Bullish Trend 2 days ago
66%
Bullish Trend 2 days ago
79%
MACD
ODDS (%)
Bearish Trend 2 days ago
67%
Bullish Trend 2 days ago
80%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
71%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
74%
Bearish Trend 2 days ago
84%
Advances
ODDS (%)
Bullish Trend 4 days ago
67%
Bullish Trend 9 days ago
88%
Declines
ODDS (%)
Bearish Trend 9 days ago
67%
Bearish Trend 7 days ago
85%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
70%
N/A
Aroon
ODDS (%)
Bullish Trend 2 days ago
75%
N/A
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IONS
Daily Signal:
Gain/Loss:
MLYS
Daily Signal:
Gain/Loss:
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IONS and

Correlation & Price change

A.I.dvisor indicates that over the last year, IONS has been loosely correlated with CYTK. These tickers have moved in lockstep 63% of the time. This A.I.-generated data suggests there is some statistical probability that if IONS jumps, then CYTK could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To IONS
1D Price
Change %
IONS100%
+0.40%
CYTK - IONS
63%
Loosely correlated
+1.41%
MLYS - IONS
49%
Loosely correlated
+0.21%
MNKD - IONS
48%
Loosely correlated
N/A
ARWR - IONS
47%
Loosely correlated
+0.40%
IDYA - IONS
47%
Loosely correlated
+0.76%
More

MLYS and

Correlation & Price change

A.I.dvisor indicates that over the last year, MLYS has been loosely correlated with CYTK. These tickers have moved in lockstep 51% of the time. This A.I.-generated data suggests there is some statistical probability that if MLYS jumps, then CYTK could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To MLYS
1D Price
Change %
MLYS100%
+0.21%
CYTK - MLYS
51%
Loosely correlated
+1.41%
IONS - MLYS
48%
Loosely correlated
+0.40%
NEVPF - MLYS
43%
Loosely correlated
N/A
PTGX - MLYS
38%
Loosely correlated
+0.12%
BIESF - MLYS
36%
Loosely correlated
N/A
More