INCY
Price
$78.80
Change
+$0.41 (+0.52%)
Updated
Aug 11, 03:45 PM (EDT)
Capitalization
15.31B
85 days until earnings call
SYRE
Price
$15.25
Change
+$0.01 (+0.07%)
Updated
Aug 11, 04:59 PM (EDT)
Capitalization
915.68M
87 days until earnings call
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INCY vs SYRE

Header iconINCY vs SYRE Comparison
Open Charts INCY vs SYREBanner chart's image
Incyte
Price$78.80
Change+$0.41 (+0.52%)
Volume$1K
Capitalization15.31B
Spyre Therapeutics
Price$15.25
Change+$0.01 (+0.07%)
Volume$2.26K
Capitalization915.68M
INCY vs SYRE Comparison Chart in %
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INCY
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
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INCY vs. SYRE commentary
Aug 11, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is INCY is a StrongBuy and SYRE is a Hold.

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COMPARISON
Comparison
Aug 11, 2025
Stock price -- (INCY: $78.39 vs. SYRE: $15.24)
Brand notoriety: INCY: Notable vs. SYRE: Not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: INCY: 69% vs. SYRE: 70%
Market capitalization -- INCY: $15.31B vs. SYRE: $915.68M
INCY [@Biotechnology] is valued at $15.31B. SYRE’s [@Biotechnology] market capitalization is $915.68M. The market cap for tickers in the [@Biotechnology] industry ranges from $93.98B to $0. The average market capitalization across the [@Biotechnology] industry is $1.78B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

INCY’s FA Score shows that 1 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • INCY’s FA Score: 1 green, 4 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, INCY is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

INCY’s TA Score shows that 5 TA indicator(s) are bullish while SYRE’s TA Score has 4 bullish TA indicator(s).

  • INCY’s TA Score: 5 bullish, 4 bearish.
  • SYRE’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, INCY is a better buy in the short-term than SYRE.

Price Growth

INCY (@Biotechnology) experienced а +3.70% price change this week, while SYRE (@Biotechnology) price change was -6.27% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +22.35%. For the same industry, the average monthly price growth was +31.87%, and the average quarterly price growth was +19.42%.

Reported Earning Dates

INCY is expected to report earnings on Nov 04, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+22.35% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
INCY($15.3B) has a higher market cap than SYRE($916M). INCY has higher P/E ratio than SYRE: INCY (18.53) vs SYRE (1.68). INCY YTD gains are higher at: 13.494 vs. SYRE (-34.536). INCY has higher annual earnings (EBITDA): 1.36B vs. SYRE (-214.36M). INCY has more cash in the bank: 2.42B vs. SYRE (565M). SYRE has less debt than INCY: SYRE (0) vs INCY (42.4M). INCY has higher revenues than SYRE: INCY (4.59B) vs SYRE (0).
INCYSYREINCY / SYRE
Capitalization15.3B916M1,670%
EBITDA1.36B-214.36M-632%
Gain YTD13.494-34.536-39%
P/E Ratio18.531.681,100%
Revenue4.59B0-
Total Cash2.42B565M429%
Total Debt42.4M0-
FUNDAMENTALS RATINGS
INCY vs SYRE: Fundamental Ratings
INCY
SYRE
OUTLOOK RATING
1..100
5050
VALUATION
overvalued / fair valued / undervalued
1..100
61
Fair valued
75
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
4099
PRICE GROWTH RATING
1..100
964
P/E GROWTH RATING
1..100
10083
SEASONALITY SCORE
1..100
50n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

INCY's Valuation (61) in the Biotechnology industry is in the same range as SYRE (75) in the Pharmaceuticals Major industry. This means that INCY’s stock grew similarly to SYRE’s over the last 12 months.

INCY's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as SYRE (100) in the Pharmaceuticals Major industry. This means that INCY’s stock grew similarly to SYRE’s over the last 12 months.

INCY's SMR Rating (40) in the Biotechnology industry is somewhat better than the same rating for SYRE (99) in the Pharmaceuticals Major industry. This means that INCY’s stock grew somewhat faster than SYRE’s over the last 12 months.

INCY's Price Growth Rating (9) in the Biotechnology industry is somewhat better than the same rating for SYRE (64) in the Pharmaceuticals Major industry. This means that INCY’s stock grew somewhat faster than SYRE’s over the last 12 months.

SYRE's P/E Growth Rating (83) in the Pharmaceuticals Major industry is in the same range as INCY (100) in the Biotechnology industry. This means that SYRE’s stock grew similarly to INCY’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
INCYSYRE
RSI
ODDS (%)
Bearish Trend 4 days ago
47%
N/A
Stochastic
ODDS (%)
Bearish Trend 4 days ago
58%
Bullish Trend 4 days ago
79%
Momentum
ODDS (%)
Bullish Trend 4 days ago
65%
Bearish Trend 4 days ago
88%
MACD
ODDS (%)
Bullish Trend 4 days ago
66%
Bearish Trend 4 days ago
90%
TrendWeek
ODDS (%)
Bullish Trend 4 days ago
64%
Bearish Trend 4 days ago
87%
TrendMonth
ODDS (%)
Bullish Trend 4 days ago
60%
Bearish Trend 4 days ago
89%
Advances
ODDS (%)
Bullish Trend 4 days ago
60%
Bullish Trend 20 days ago
85%
Declines
ODDS (%)
Bearish Trend 6 days ago
61%
Bearish Trend 4 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 4 days ago
60%
Bullish Trend 4 days ago
85%
Aroon
ODDS (%)
Bullish Trend 4 days ago
61%
Bullish Trend 4 days ago
87%
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INCY
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
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INCY and

Correlation & Price change

A.I.dvisor indicates that over the last year, INCY has been loosely correlated with TECH. These tickers have moved in lockstep 40% of the time. This A.I.-generated data suggests there is some statistical probability that if INCY jumps, then TECH could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To INCY
1D Price
Change %
INCY100%
+0.24%
TECH - INCY
40%
Loosely correlated
+0.54%
REGN - INCY
39%
Loosely correlated
+0.57%
SYRE - INCY
37%
Loosely correlated
N/A
AGIO - INCY
37%
Loosely correlated
-3.51%
RPRX - INCY
37%
Loosely correlated
+1.54%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with IDYA. These tickers have moved in lockstep 60% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
N/A
IDYA - SYRE
60%
Loosely correlated
+3.08%
CGON - SYRE
60%
Loosely correlated
+2.05%
BEAM - SYRE
59%
Loosely correlated
-1.34%
XNCR - SYRE
57%
Loosely correlated
-1.23%
CRNX - SYRE
55%
Loosely correlated
-3.69%
More