HRTX
Price
$1.11
Change
-$0.00 (-0.00%)
Updated
Nov 13 closing price
Capitalization
202.62M
110 days until earnings call
Intraday BUY SELL Signals
PBYI
Price
$4.95
Change
-$0.04 (-0.80%)
Updated
Nov 13 closing price
Capitalization
249.44M
104 days until earnings call
Intraday BUY SELL Signals
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HRTX vs PBYI

Header iconHRTX vs PBYI Comparison
Open Charts HRTX vs PBYIBanner chart's image
Heron Therapeutics
Price$1.11
Change-$0.00 (-0.00%)
Volume$1.64M
Capitalization202.62M
Puma Biotechnology
Price$4.95
Change-$0.04 (-0.80%)
Volume$657.16K
Capitalization249.44M
HRTX vs PBYI Comparison Chart in %
HRTX
Daily Signal:
Gain/Loss:
PBYI
Daily Signal:
Gain/Loss:
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HRTX vs. PBYI commentary
Nov 14, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is HRTX is a Hold and PBYI is a Hold.

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COMPARISON
Comparison
Nov 14, 2025
Stock price -- (HRTX: $1.11 vs. PBYI: $4.95)
Brand notoriety: HRTX and PBYI are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: HRTX: 95% vs. PBYI: 117%
Market capitalization -- HRTX: $202.62M vs. PBYI: $249.44M
HRTX [@Biotechnology] is valued at $202.62M. PBYI’s [@Biotechnology] market capitalization is $249.44M. The market cap for tickers in the [@Biotechnology] industry ranges from $110.25B to $0. The average market capitalization across the [@Biotechnology] industry is $2.11B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

HRTX’s FA Score shows that 0 FA rating(s) are green whilePBYI’s FA Score has 1 green FA rating(s).

  • HRTX’s FA Score: 0 green, 5 red.
  • PBYI’s FA Score: 1 green, 4 red.
According to our system of comparison, PBYI is a better buy in the long-term than HRTX.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

HRTX’s TA Score shows that 3 TA indicator(s) are bullish while PBYI’s TA Score has 3 bullish TA indicator(s).

  • HRTX’s TA Score: 3 bullish, 6 bearish.
  • PBYI’s TA Score: 3 bullish, 6 bearish.
According to our system of comparison, both HRTX and PBYI are a bad buy in the short-term.

Price Growth

HRTX (@Biotechnology) experienced а +0.91% price change this week, while PBYI (@Biotechnology) price change was +1.02% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.47%. For the same industry, the average monthly price growth was -3.12%, and the average quarterly price growth was +62.00%.

Reported Earning Dates

HRTX is expected to report earnings on Mar 04, 2026.

PBYI is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+1.47% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PBYI($249M) has a higher market cap than HRTX($203M). PBYI YTD gains are higher at: 63.607 vs. HRTX (-27.451). PBYI has higher annual earnings (EBITDA): 63.3M vs. HRTX (7.54M). PBYI has more cash in the bank: 96M vs. HRTX (40.6M). PBYI has less debt than HRTX: PBYI (49.2M) vs HRTX (177M). PBYI has higher revenues than HRTX: PBYI (238M) vs HRTX (150M).
HRTXPBYIHRTX / PBYI
Capitalization203M249M82%
EBITDA7.54M63.3M12%
Gain YTD-27.45163.607-43%
P/E RatioN/A6.69-
Revenue150M238M63%
Total Cash40.6M96M42%
Total Debt177M49.2M360%
FUNDAMENTALS RATINGS
HRTX vs PBYI: Fundamental Ratings
HRTX
PBYI
OUTLOOK RATING
1..100
1076
VALUATION
overvalued / fair valued / undervalued
1..100
71
Overvalued
49
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
10017
PRICE GROWTH RATING
1..100
8542
P/E GROWTH RATING
1..100
10096
SEASONALITY SCORE
1..100
75n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

PBYI's Valuation (49) in the Biotechnology industry is in the same range as HRTX (71). This means that PBYI’s stock grew similarly to HRTX’s over the last 12 months.

PBYI's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as HRTX (100). This means that PBYI’s stock grew similarly to HRTX’s over the last 12 months.

PBYI's SMR Rating (17) in the Biotechnology industry is significantly better than the same rating for HRTX (100). This means that PBYI’s stock grew significantly faster than HRTX’s over the last 12 months.

PBYI's Price Growth Rating (42) in the Biotechnology industry is somewhat better than the same rating for HRTX (85). This means that PBYI’s stock grew somewhat faster than HRTX’s over the last 12 months.

PBYI's P/E Growth Rating (96) in the Biotechnology industry is in the same range as HRTX (100). This means that PBYI’s stock grew similarly to HRTX’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
HRTXPBYI
RSI
ODDS (%)
N/A
Bearish Trend 3 days ago
86%
Stochastic
ODDS (%)
Bullish Trend 3 days ago
85%
Bullish Trend 3 days ago
83%
Momentum
ODDS (%)
Bearish Trend 3 days ago
86%
Bearish Trend 3 days ago
83%
MACD
ODDS (%)
Bearish Trend 3 days ago
82%
Bearish Trend 3 days ago
88%
TrendWeek
ODDS (%)
Bullish Trend 3 days ago
82%
Bullish Trend 3 days ago
84%
TrendMonth
ODDS (%)
Bearish Trend 3 days ago
86%
Bearish Trend 3 days ago
84%
Advances
ODDS (%)
Bullish Trend 4 days ago
84%
Bullish Trend 19 days ago
87%
Declines
ODDS (%)
Bearish Trend 9 days ago
88%
Bearish Trend 11 days ago
84%
BollingerBands
ODDS (%)
Bullish Trend 3 days ago
80%
Bearish Trend 3 days ago
90%
Aroon
ODDS (%)
Bearish Trend 3 days ago
85%
Bullish Trend 3 days ago
71%
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HRTX
Daily Signal:
Gain/Loss:
PBYI
Daily Signal:
Gain/Loss:
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HRTX and

Correlation & Price change

A.I.dvisor indicates that over the last year, HRTX has been loosely correlated with GSGTF. These tickers have moved in lockstep 45% of the time. This A.I.-generated data suggests there is some statistical probability that if HRTX jumps, then GSGTF could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To HRTX
1D Price
Change %
HRTX100%
-4.31%
GSGTF - HRTX
45%
Loosely correlated
N/A
AMRN - HRTX
44%
Loosely correlated
+0.75%
CYCN - HRTX
41%
Loosely correlated
-11.80%
AXON - HRTX
38%
Loosely correlated
-0.47%
LGVN - HRTX
37%
Loosely correlated
-1.34%
More

PBYI and

Correlation & Price change

A.I.dvisor indicates that over the last year, PBYI has been loosely correlated with MTNB. These tickers have moved in lockstep 37% of the time. This A.I.-generated data suggests there is some statistical probability that if PBYI jumps, then MTNB could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PBYI
1D Price
Change %
PBYI100%
-3.85%
MTNB - PBYI
37%
Loosely correlated
+5.83%
ARWR - PBYI
33%
Loosely correlated
-0.19%
DSGN - PBYI
32%
Poorly correlated
-1.93%
HRTX - PBYI
32%
Poorly correlated
-4.31%
NVAX - PBYI
30%
Poorly correlated
-3.23%
More