HOWL
Price
$1.16
Change
-$0.02 (-1.71%)
Updated
Aug 11, 03:23 PM (EDT)
Capitalization
52.5M
Earnings call today
SYRE
Price
$15.25
Change
+$0.01 (+0.07%)
Updated
Aug 11, 04:59 PM (EDT)
Capitalization
915.68M
87 days until earnings call
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HOWL vs SYRE

Header iconHOWL vs SYRE Comparison
Open Charts HOWL vs SYREBanner chart's image
Werewolf Therapeutics
Price$1.16
Change-$0.02 (-1.71%)
Volume$1.15K
Capitalization52.5M
Spyre Therapeutics
Price$15.25
Change+$0.01 (+0.07%)
Volume$2.26K
Capitalization915.68M
HOWL vs SYRE Comparison Chart in %
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HOWL
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
Gain/Loss if bought
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HOWL vs. SYRE commentary
Aug 12, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is HOWL is a Hold and SYRE is a Hold.

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COMPARISON
Comparison
Aug 12, 2025
Stock price -- (HOWL: $1.17 vs. SYRE: $15.24)
Brand notoriety: HOWL and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: HOWL: 38% vs. SYRE: 70%
Market capitalization -- HOWL: $52.5M vs. SYRE: $915.68M
HOWL [@Biotechnology] is valued at $52.5M. SYRE’s [@Biotechnology] market capitalization is $915.68M. The market cap for tickers in the [@Biotechnology] industry ranges from $93.98B to $0. The average market capitalization across the [@Biotechnology] industry is $1.78B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

HOWL’s FA Score shows that 1 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • HOWL’s FA Score: 1 green, 4 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, HOWL is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

HOWL’s TA Score shows that 3 TA indicator(s) are bullish while SYRE’s TA Score has 4 bullish TA indicator(s).

  • HOWL’s TA Score: 3 bullish, 7 bearish.
  • SYRE’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, SYRE is a better buy in the short-term than HOWL.

Price Growth

HOWL (@Biotechnology) experienced а +0.86% price change this week, while SYRE (@Biotechnology) price change was -6.27% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +22.22%. For the same industry, the average monthly price growth was +31.78%, and the average quarterly price growth was +19.63%.

Reported Earning Dates

HOWL is expected to report earnings on Aug 11, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+22.22% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($916M) has a higher market cap than HOWL($52.5M). HOWL YTD gains are higher at: -20.946 vs. SYRE (-34.536). HOWL has higher annual earnings (EBITDA): -65.72M vs. SYRE (-214.36M). SYRE has more cash in the bank: 565M vs. HOWL (92M). SYRE has less debt than HOWL: SYRE (0) vs HOWL (37M). HOWL has higher revenues than SYRE: HOWL (1.14M) vs SYRE (0).
HOWLSYREHOWL / SYRE
Capitalization52.5M916M6%
EBITDA-65.72M-214.36M31%
Gain YTD-20.946-34.53661%
P/E RatioN/A1.68-
Revenue1.14M0-
Total Cash92M565M16%
Total Debt37M0-
FUNDAMENTALS RATINGS
SYRE: Fundamental Ratings
SYRE
OUTLOOK RATING
1..100
50
VALUATION
overvalued / fair valued / undervalued
1..100
75
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
99
PRICE GROWTH RATING
1..100
64
P/E GROWTH RATING
1..100
83
SEASONALITY SCORE
1..100
n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
HOWLSYRE
RSI
ODDS (%)
Bearish Trend 4 days ago
89%
N/A
Stochastic
ODDS (%)
Bullish Trend 4 days ago
83%
Bullish Trend 4 days ago
79%
Momentum
ODDS (%)
Bearish Trend 4 days ago
87%
Bearish Trend 4 days ago
88%
MACD
ODDS (%)
Bearish Trend 4 days ago
90%
Bearish Trend 4 days ago
90%
TrendWeek
ODDS (%)
Bullish Trend 4 days ago
82%
Bearish Trend 4 days ago
87%
TrendMonth
ODDS (%)
Bullish Trend 4 days ago
84%
Bearish Trend 4 days ago
89%
Advances
ODDS (%)
Bullish Trend 25 days ago
81%
Bullish Trend 20 days ago
85%
Declines
ODDS (%)
Bearish Trend 4 days ago
90%
Bearish Trend 4 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 4 days ago
74%
Bullish Trend 4 days ago
85%
Aroon
ODDS (%)
Bearish Trend 4 days ago
90%
Bullish Trend 4 days ago
87%
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HOWL
Daily Signalchanged days ago
Gain/Loss if bought
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SYRE
Daily Signalchanged days ago
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HOWL and

Correlation & Price change

A.I.dvisor indicates that over the last year, HOWL has been loosely correlated with IPSC. These tickers have moved in lockstep 42% of the time. This A.I.-generated data suggests there is some statistical probability that if HOWL jumps, then IPSC could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To HOWL
1D Price
Change %
HOWL100%
-0.85%
IPSC - HOWL
42%
Loosely correlated
-4.14%
GBIO - HOWL
41%
Loosely correlated
-1.20%
CLDX - HOWL
39%
Loosely correlated
-2.59%
GNPX - HOWL
39%
Loosely correlated
-3.43%
SYRE - HOWL
38%
Loosely correlated
N/A
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with IDYA. These tickers have moved in lockstep 60% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
N/A
IDYA - SYRE
60%
Loosely correlated
+3.08%
CGON - SYRE
60%
Loosely correlated
+2.05%
BEAM - SYRE
59%
Loosely correlated
-1.34%
XNCR - SYRE
57%
Loosely correlated
-1.23%
CRNX - SYRE
55%
Loosely correlated
-3.69%
More