HOTH
Price
$1.20
Change
+$0.06 (+5.26%)
Updated
Dec 3 closing price
Capitalization
18.62M
Intraday BUY SELL Signals
LYEL
Price
$22.31
Change
+$1.50 (+7.21%)
Updated
Dec 3 closing price
Capitalization
473.38M
Intraday BUY SELL Signals
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HOTH vs LYEL

Header iconHOTH vs LYEL Comparison
Open Charts HOTH vs LYELBanner chart's image
Hoth Therapeutics
Price$1.20
Change+$0.06 (+5.26%)
Volume$277.56K
Capitalization18.62M
Lyell Immunopharma
Price$22.31
Change+$1.50 (+7.21%)
Volume$54.22K
Capitalization473.38M
HOTH vs LYEL Comparison Chart in %
HOTH
Daily Signal:
Gain/Loss:
LYEL
Daily Signal:
Gain/Loss:
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VS
HOTH vs. LYEL commentary
Dec 04, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is HOTH is a Buy and LYEL is a StrongBuy.

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COMPARISON
Comparison
Dec 04, 2025
Stock price -- (HOTH: $1.14 vs. LYEL: $20.62)
Brand notoriety: HOTH and LYEL are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: HOTH: 11% vs. LYEL: 47%
Market capitalization -- HOTH: $18.62M vs. LYEL: $473.38M
HOTH [@Biotechnology] is valued at $18.62M. LYEL’s [@Biotechnology] market capitalization is $473.38M. The market cap for tickers in the [@Biotechnology] industry ranges from $117.5B to $0. The average market capitalization across the [@Biotechnology] industry is $2.19B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

HOTH’s FA Score shows that 1 FA rating(s) are green whileLYEL’s FA Score has 0 green FA rating(s).

  • HOTH’s FA Score: 1 green, 4 red.
  • LYEL’s FA Score: 0 green, 5 red.
According to our system of comparison, HOTH is a better buy in the long-term than LYEL.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

HOTH’s TA Score shows that 5 TA indicator(s) are bullish while LYEL’s TA Score has 3 bullish TA indicator(s).

  • HOTH’s TA Score: 5 bullish, 3 bearish.
  • LYEL’s TA Score: 3 bullish, 4 bearish.
According to our system of comparison, HOTH is a better buy in the short-term than LYEL.

Price Growth

HOTH (@Biotechnology) experienced а -2.56% price change this week, while LYEL (@Biotechnology) price change was -8.48% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.32%. For the same industry, the average monthly price growth was +1.23%, and the average quarterly price growth was +54.93%.

Industries' Descriptions

@Biotechnology (+0.32% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
LYEL($473M) has a higher market cap than HOTH($18.6M). LYEL YTD gains are higher at: 61.094 vs. HOTH (52.386). HOTH has higher annual earnings (EBITDA): -10.09M vs. LYEL (-199.95M). LYEL has more cash in the bank: 277M vs. HOTH (9.01M). HOTH has less debt than LYEL: HOTH (21.3K) vs LYEL (46.6M). LYEL has higher revenues than HOTH: LYEL (60K) vs HOTH (0).
HOTHLYELHOTH / LYEL
Capitalization18.6M473M4%
EBITDA-10.09M-199.95M5%
Gain YTD52.38661.09486%
P/E RatioN/AN/A-
Revenue060K-
Total Cash9.01M277M3%
Total Debt21.3K46.6M0%
FUNDAMENTALS RATINGS
HOTH: Fundamental Ratings
HOTH
OUTLOOK RATING
1..100
50
VALUATION
overvalued / fair valued / undervalued
1..100
21
Undervalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
98
PRICE GROWTH RATING
1..100
47
P/E GROWTH RATING
1..100
100
SEASONALITY SCORE
1..100
75

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
HOTHLYEL
RSI
ODDS (%)
Bullish Trend 7 days ago
90%
Bearish Trend 7 days ago
84%
Stochastic
ODDS (%)
Bearish Trend 7 days ago
90%
Bearish Trend 7 days ago
89%
Momentum
ODDS (%)
Bullish Trend 7 days ago
78%
Bullish Trend 7 days ago
82%
MACD
ODDS (%)
Bullish Trend 7 days ago
84%
Bullish Trend 7 days ago
76%
TrendWeek
ODDS (%)
Bullish Trend 7 days ago
82%
Bullish Trend 7 days ago
85%
TrendMonth
ODDS (%)
Bearish Trend 7 days ago
90%
Bullish Trend 7 days ago
87%
Advances
ODDS (%)
Bullish Trend 7 days ago
82%
Bullish Trend 11 days ago
84%
Declines
ODDS (%)
Bearish Trend 15 days ago
90%
Bearish Trend 21 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 7 days ago
86%
Bearish Trend 7 days ago
90%
Aroon
ODDS (%)
Bearish Trend 7 days ago
90%
N/A
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HOTH
Daily Signal:
Gain/Loss:
LYEL
Daily Signal:
Gain/Loss:
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HOTH and

Correlation & Price change

A.I.dvisor tells us that HOTH and PPTDF have been poorly correlated (+32% of the time) for the last year. This A.I.-generated data suggests there is low statistical probability that HOTH and PPTDF's prices will move in lockstep.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To HOTH
1D Price
Change %
HOTH100%
N/A
PPTDF - HOTH
32%
Poorly correlated
N/A
NRXP - HOTH
30%
Poorly correlated
-5.00%
AIM - HOTH
30%
Poorly correlated
-9.68%
CRMD - HOTH
30%
Poorly correlated
+0.05%
LYEL - HOTH
30%
Poorly correlated
-6.70%
More

LYEL and

Correlation & Price change

A.I.dvisor indicates that over the last year, LYEL has been loosely correlated with VCYT. These tickers have moved in lockstep 46% of the time. This A.I.-generated data suggests there is some statistical probability that if LYEL jumps, then VCYT could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To LYEL
1D Price
Change %
LYEL100%
-6.70%
VCYT - LYEL
46%
Loosely correlated
-0.43%
RLYB - LYEL
41%
Loosely correlated
-0.25%
CRBU - LYEL
36%
Loosely correlated
-0.56%
BEAM - LYEL
36%
Loosely correlated
-2.83%
RXRX - LYEL
35%
Loosely correlated
-0.69%
More