GYRE
Price
$7.72
Change
-$0.02 (-0.26%)
Updated
Sep 2, 04:34 PM (EDT)
Capitalization
703M
71 days until earnings call
SPHDF
Price
$18.40
Change
+$3.65 (+24.75%)
Updated
Jul 28 closing price
Capitalization
222.58M
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GYRE vs SPHDF

Header iconGYRE vs SPHDF Comparison
Open Charts GYRE vs SPHDFBanner chart's image
Gyre Therapeutics
Price$7.72
Change-$0.02 (-0.26%)
Volume$288
Capitalization703M
Santhera Pharmaceuticals Holdings
Price$18.40
Change+$3.65 (+24.75%)
Volume$600
Capitalization222.58M
GYRE vs SPHDF Comparison Chart in %
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GYRE
Daily Signalchanged days ago
Gain/Loss if bought
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SPHDF
Daily Signalchanged days ago
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GYRE vs. SPHDF commentary
Sep 02, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is GYRE is a StrongBuy and SPHDF is a Hold.

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COMPARISON
Comparison
Sep 02, 2025
Stock price -- (GYRE: $7.74 vs. SPHDF: $18.40)
Brand notoriety: GYRE and SPHDF are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: GYRE: 64% vs. SPHDF: 133%
Market capitalization -- GYRE: $703M vs. SPHDF: $222.58M
GYRE [@Biotechnology] is valued at $703M. SPHDF’s [@Biotechnology] market capitalization is $222.58M. The market cap for tickers in the [@Biotechnology] industry ranges from $100.25B to $0. The average market capitalization across the [@Biotechnology] industry is $1.85B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

GYRE’s FA Score shows that 1 FA rating(s) are green whileSPHDF’s FA Score has 1 green FA rating(s).

  • GYRE’s FA Score: 1 green, 4 red.
  • SPHDF’s FA Score: 1 green, 4 red.
According to our system of comparison, SPHDF is a better buy in the long-term than GYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

GYRE’s TA Score shows that 5 TA indicator(s) are bullish while SPHDF’s TA Score has 4 bullish TA indicator(s).

  • GYRE’s TA Score: 5 bullish, 4 bearish.
  • SPHDF’s TA Score: 4 bullish, 2 bearish.
According to our system of comparison, GYRE is a better buy in the short-term than SPHDF.

Price Growth

GYRE (@Biotechnology) experienced а -5.38% price change this week, while SPHDF (@Biotechnology) price change was 0.00% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +6.83%. For the same industry, the average monthly price growth was +22.37%, and the average quarterly price growth was +32.94%.

Reported Earning Dates

GYRE is expected to report earnings on Nov 12, 2025.

Industries' Descriptions

@Biotechnology (+6.83% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
GYRE($703M) has a higher market cap than SPHDF($223M). GYRE has higher P/E ratio than SPHDF: GYRE (387.00) vs SPHDF (2.52). SPHDF YTD gains are higher at: 95.329 vs. GYRE (-36.033).
GYRESPHDFGYRE / SPHDF
Capitalization703M223M315%
EBITDA11.5MN/A-
Gain YTD-36.03395.329-38%
P/E Ratio387.002.5215,362%
Revenue102MN/A-
Total Cash54.4MN/A-
Total Debt1.39MN/A-
FUNDAMENTALS RATINGS
GYRE vs SPHDF: Fundamental Ratings
GYRE
SPHDF
OUTLOOK RATING
1..100
5050
VALUATION
overvalued / fair valued / undervalued
1..100
93
Overvalued
59
Fair valued
PROFIT vs RISK RATING
1..100
89100
SMR RATING
1..100
84100
PRICE GROWTH RATING
1..100
6439
P/E GROWTH RATING
1..100
811
SEASONALITY SCORE
1..100
8522

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SPHDF's Valuation (59) in the null industry is somewhat better than the same rating for GYRE (93). This means that SPHDF’s stock grew somewhat faster than GYRE’s over the last 12 months.

GYRE's Profit vs Risk Rating (89) in the null industry is in the same range as SPHDF (100). This means that GYRE’s stock grew similarly to SPHDF’s over the last 12 months.

GYRE's SMR Rating (84) in the null industry is in the same range as SPHDF (100). This means that GYRE’s stock grew similarly to SPHDF’s over the last 12 months.

SPHDF's Price Growth Rating (39) in the null industry is in the same range as GYRE (64). This means that SPHDF’s stock grew similarly to GYRE’s over the last 12 months.

GYRE's P/E Growth Rating (8) in the null industry is in the same range as SPHDF (11). This means that GYRE’s stock grew similarly to SPHDF’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
GYRESPHDF
RSI
ODDS (%)
N/A
Bearish Trend 7 days ago
67%
Stochastic
ODDS (%)
Bearish Trend 5 days ago
86%
Bullish Trend 5 days ago
21%
Momentum
ODDS (%)
Bearish Trend 5 days ago
82%
N/A
MACD
ODDS (%)
Bullish Trend 5 days ago
82%
Bearish Trend 5 days ago
65%
TrendWeek
ODDS (%)
Bearish Trend 5 days ago
86%
Bullish Trend 5 days ago
12%
TrendMonth
ODDS (%)
Bullish Trend 5 days ago
82%
Bullish Trend 5 days ago
14%
Advances
ODDS (%)
Bullish Trend 6 days ago
82%
N/A
Declines
ODDS (%)
Bearish Trend 15 days ago
84%
N/A
BollingerBands
ODDS (%)
Bearish Trend 5 days ago
86%
N/A
Aroon
ODDS (%)
Bullish Trend 5 days ago
79%
Bullish Trend 5 days ago
11%
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GYRE
Daily Signalchanged days ago
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SPHDF
Daily Signalchanged days ago
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GYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, GYRE has been closely correlated with SPHDF. These tickers have moved in lockstep 82% of the time. This A.I.-generated data suggests there is a high statistical probability that if GYRE jumps, then SPHDF could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To GYRE
1D Price
Change %
GYRE100%
-6.52%
SPHDF - GYRE
82%
Closely correlated
N/A
SPRC - GYRE
38%
Loosely correlated
-18.81%
BEAM - GYRE
38%
Loosely correlated
-2.91%
RCKT - GYRE
35%
Loosely correlated
-2.09%
AURA - GYRE
35%
Loosely correlated
-2.64%
More

SPHDF and

Correlation & Price change

A.I.dvisor indicates that over the last year, SPHDF has been closely correlated with GYRE. These tickers have moved in lockstep 82% of the time. This A.I.-generated data suggests there is a high statistical probability that if SPHDF jumps, then GYRE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SPHDF
1D Price
Change %
SPHDF100%
N/A
GYRE - SPHDF
82%
Closely correlated
-6.52%
HRMY - SPHDF
37%
Loosely correlated
-2.84%
SPRC - SPHDF
34%
Loosely correlated
-18.81%
INM - SPHDF
33%
Poorly correlated
+1.83%
RVMD - SPHDF
33%
Poorly correlated
-0.93%
More