EWTX
Price
$20.42
Change
-$0.75 (-3.54%)
Updated
Nov 13 closing price
Capitalization
2.16B
97 days until earnings call
Intraday BUY SELL Signals
SYRE
Price
$22.63
Change
-$0.80 (-3.41%)
Updated
Nov 13 closing price
Capitalization
1.76B
104 days until earnings call
Intraday BUY SELL Signals
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EWTX vs SYRE

Header iconEWTX vs SYRE Comparison
Open Charts EWTX vs SYREBanner chart's image
Edgewise Therapeutics
Price$20.42
Change-$0.75 (-3.54%)
Volume$1.09M
Capitalization2.16B
Spyre Therapeutics
Price$22.63
Change-$0.80 (-3.41%)
Volume$514.56K
Capitalization1.76B
EWTX vs SYRE Comparison Chart in %
EWTX
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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VS
EWTX vs. SYRE commentary
Nov 14, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is EWTX is a Hold and SYRE is a Buy.

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COMPARISON
Comparison
Nov 14, 2025
Stock price -- (EWTX: $21.17 vs. SYRE: $23.43)
Brand notoriety: EWTX and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: EWTX: 199% vs. SYRE: 64%
Market capitalization -- EWTX: $2.16B vs. SYRE: $1.76B
EWTX [@Biotechnology] is valued at $2.16B. SYRE’s [@Biotechnology] market capitalization is $1.76B. The market cap for tickers in the [@Biotechnology] industry ranges from $110.25B to $0. The average market capitalization across the [@Biotechnology] industry is $2.1B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

EWTX’s FA Score shows that 1 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • EWTX’s FA Score: 1 green, 4 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, EWTX is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

EWTX’s TA Score shows that 4 TA indicator(s) are bullish while SYRE’s TA Score has 5 bullish TA indicator(s).

  • EWTX’s TA Score: 4 bullish, 4 bearish.
  • SYRE’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, both EWTX and SYRE are a good buy in the short-term.

Price Growth

EWTX (@Biotechnology) experienced а +21.88% price change this week, while SYRE (@Biotechnology) price change was +2.54% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.51%. For the same industry, the average monthly price growth was -3.12%, and the average quarterly price growth was +61.90%.

Reported Earning Dates

EWTX is expected to report earnings on Feb 19, 2026.

SYRE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+1.51% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
EWTX($2.16B) has a higher market cap than SYRE($1.76B). SYRE YTD gains are higher at: 0.644 vs. EWTX (-20.712). EWTX has higher annual earnings (EBITDA): -172.19M vs. SYRE (-222.15M). EWTX has more cash in the bank: 594M vs. SYRE (527M). SYRE has less debt than EWTX: SYRE (0) vs EWTX (4.37M). EWTX (0) and SYRE (0) have equivalent revenues.
EWTXSYREEWTX / SYRE
Capitalization2.16B1.76B123%
EBITDA-172.19M-222.15M78%
Gain YTD-20.7120.644-3,214%
P/E RatioN/A1.72-
Revenue00-
Total Cash594M527M113%
Total Debt4.37M0-
FUNDAMENTALS RATINGS
SYRE: Fundamental Ratings
SYRE
OUTLOOK RATING
1..100
86
VALUATION
overvalued / fair valued / undervalued
1..100
68
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
97
PRICE GROWTH RATING
1..100
40
P/E GROWTH RATING
1..100
77
SEASONALITY SCORE
1..100
85

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
EWTXSYRE
RSI
ODDS (%)
Bearish Trend 2 days ago
87%
Bearish Trend 2 days ago
88%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
84%
Bullish Trend 2 days ago
89%
Momentum
ODDS (%)
Bullish Trend 2 days ago
81%
Bearish Trend 2 days ago
90%
MACD
ODDS (%)
Bullish Trend 2 days ago
82%
Bearish Trend 2 days ago
87%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
84%
Bullish Trend 2 days ago
82%
Advances
ODDS (%)
Bullish Trend 3 days ago
83%
Bullish Trend 2 days ago
84%
Declines
ODDS (%)
Bearish Trend 10 days ago
89%
Bearish Trend 8 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
81%
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
Bullish Trend 2 days ago
90%
Bullish Trend 2 days ago
86%
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EWTX
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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EWTX and

Correlation & Price change

A.I.dvisor indicates that over the last year, EWTX has been loosely correlated with SYRE. These tickers have moved in lockstep 39% of the time. This A.I.-generated data suggests there is some statistical probability that if EWTX jumps, then SYRE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To EWTX
1D Price
Change %
EWTX100%
-1.44%
SYRE - EWTX
39%
Loosely correlated
+0.34%
APGE - EWTX
37%
Loosely correlated
+0.24%
IMVT - EWTX
37%
Loosely correlated
+2.40%
TERN - EWTX
36%
Loosely correlated
-1.36%
CGON - EWTX
35%
Loosely correlated
+1.47%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with APGE. These tickers have moved in lockstep 59% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then APGE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+0.34%
APGE - SYRE
59%
Loosely correlated
+0.24%
CGON - SYRE
58%
Loosely correlated
+1.47%
IDYA - SYRE
57%
Loosely correlated
-0.19%
RGNX - SYRE
56%
Loosely correlated
+0.43%
NRIX - SYRE
56%
Loosely correlated
-5.37%
More