DSGN
Price
$9.74
Change
+$0.14 (+1.46%)
Updated
Dec 24 closing price
Capitalization
554.83M
82 days until earnings call
Intraday BUY SELL Signals
PBYI
Price
$5.96
Change
+$0.05 (+0.85%)
Updated
Dec 24 closing price
Capitalization
300.33M
63 days until earnings call
Intraday BUY SELL Signals
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DSGN vs PBYI

Header iconDSGN vs PBYI Comparison
Open Charts DSGN vs PBYIBanner chart's image
Design Therapeutics
Price$9.74
Change+$0.14 (+1.46%)
Volume$136.07K
Capitalization554.83M
Puma Biotechnology
Price$5.96
Change+$0.05 (+0.85%)
Volume$180.45K
Capitalization300.33M
DSGN vs PBYI Comparison Chart in %
DSGN
Daily Signal:
Gain/Loss:
PBYI
Daily Signal:
Gain/Loss:
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VS
DSGN vs. PBYI commentary
Dec 26, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is DSGN is a Buy and PBYI is a Buy.

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COMPARISON
Comparison
Dec 26, 2025
Stock price -- (DSGN: $9.74 vs. PBYI: $5.96)
Brand notoriety: DSGN and PBYI are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: DSGN: 33% vs. PBYI: 36%
Market capitalization -- DSGN: $554.83M vs. PBYI: $300.33M
DSGN [@Biotechnology] is valued at $554.83M. PBYI’s [@Biotechnology] market capitalization is $300.33M. The market cap for tickers in the [@Biotechnology] industry ranges from $117.47B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

DSGN’s FA Score shows that 0 FA rating(s) are green whilePBYI’s FA Score has 2 green FA rating(s).

  • DSGN’s FA Score: 0 green, 5 red.
  • PBYI’s FA Score: 2 green, 3 red.
According to our system of comparison, PBYI is a better buy in the long-term than DSGN.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

DSGN’s TA Score shows that 3 TA indicator(s) are bullish while PBYI’s TA Score has 6 bullish TA indicator(s).

  • DSGN’s TA Score: 3 bullish, 4 bearish.
  • PBYI’s TA Score: 6 bullish, 4 bearish.
According to our system of comparison, PBYI is a better buy in the short-term than DSGN.

Price Growth

DSGN (@Biotechnology) experienced а +9.93% price change this week, while PBYI (@Biotechnology) price change was +6.81% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.88%. For the same industry, the average monthly price growth was +4.46%, and the average quarterly price growth was +55.39%.

Reported Earning Dates

DSGN is expected to report earnings on Mar 17, 2026.

PBYI is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+2.88% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
DSGN($555M) has a higher market cap than PBYI($300M). PBYI YTD gains are higher at: 95.410 vs. DSGN (57.861). PBYI has higher annual earnings (EBITDA): 50.2M vs. DSGN (-77.38M). DSGN has more cash in the bank: 206M vs. PBYI (94.4M). DSGN has less debt than PBYI: DSGN (1.74M) vs PBYI (41.1M). PBYI has higher revenues than DSGN: PBYI (212M) vs DSGN (0).
DSGNPBYIDSGN / PBYI
Capitalization555M300M185%
EBITDA-77.38M50.2M-154%
Gain YTD57.86195.41061%
P/E RatioN/A8.05-
Revenue0212M-
Total Cash206M94.4M218%
Total Debt1.74M41.1M4%
FUNDAMENTALS RATINGS
PBYI: Fundamental Ratings
PBYI
OUTLOOK RATING
1..100
26
VALUATION
overvalued / fair valued / undervalued
1..100
53
Fair valued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
23
PRICE GROWTH RATING
1..100
37
P/E GROWTH RATING
1..100
23
SEASONALITY SCORE
1..100
n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
DSGNPBYI
RSI
ODDS (%)
Bearish Trend 2 days ago
88%
Bearish Trend 2 days ago
89%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
88%
Bearish Trend 2 days ago
89%
Momentum
ODDS (%)
Bullish Trend 2 days ago
88%
Bullish Trend 2 days ago
88%
MACD
ODDS (%)
Bearish Trend 2 days ago
86%
Bullish Trend 2 days ago
73%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
86%
Bullish Trend 2 days ago
84%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
87%
Bullish Trend 2 days ago
83%
Advances
ODDS (%)
Bullish Trend 4 days ago
89%
Bullish Trend 2 days ago
86%
Declines
ODDS (%)
N/A
Bearish Trend 9 days ago
84%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
80%
Bearish Trend 2 days ago
90%
Aroon
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
80%
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DSGN
Daily Signal:
Gain/Loss:
PBYI
Daily Signal:
Gain/Loss:
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DSGN and

Correlation & Price change

A.I.dvisor indicates that over the last year, DSGN has been loosely correlated with IDYA. These tickers have moved in lockstep 51% of the time. This A.I.-generated data suggests there is some statistical probability that if DSGN jumps, then IDYA could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To DSGN
1D Price
Change %
DSGN100%
+1.46%
IDYA - DSGN
51%
Loosely correlated
+0.76%
SLDB - DSGN
49%
Loosely correlated
N/A
DYN - DSGN
49%
Loosely correlated
-0.29%
SYRE - DSGN
48%
Loosely correlated
-0.54%
AURA - DSGN
48%
Loosely correlated
-2.65%
More

PBYI and

Correlation & Price change

A.I.dvisor indicates that over the last year, PBYI has been loosely correlated with MTNB. These tickers have moved in lockstep 38% of the time. This A.I.-generated data suggests there is some statistical probability that if PBYI jumps, then MTNB could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PBYI
1D Price
Change %
PBYI100%
+0.85%
MTNB - PBYI
38%
Loosely correlated
+3.24%
DSGN - PBYI
35%
Loosely correlated
+1.46%
NVAX - PBYI
32%
Poorly correlated
+2.06%
RZLT - PBYI
30%
Poorly correlated
+13.22%
VRCA - PBYI
30%
Poorly correlated
+1.46%
More