DNLI
Price
$17.99
Change
-$0.79 (-4.21%)
Updated
Jan 16 closing price
Capitalization
2.81B
44 days until earnings call
Intraday BUY SELL Signals
PTGX
Price
$81.99
Change
-$2.76 (-3.26%)
Updated
Jan 16 closing price
Capitalization
5.13B
60 days until earnings call
Intraday BUY SELL Signals
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DNLI vs PTGX

Header iconDNLI vs PTGX Comparison
Open Charts DNLI vs PTGXBanner chart's image
Denali Therapeutics
Price$17.99
Change-$0.79 (-4.21%)
Volume$1.39M
Capitalization2.81B
Protagonist Therapeutics
Price$81.99
Change-$2.76 (-3.26%)
Volume$664.93K
Capitalization5.13B
DNLI vs PTGX Comparison Chart in %
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DNLI vs. PTGX commentary
Jan 18, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is DNLI is a Hold and PTGX is a Hold.

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COMPARISON
Comparison
Jan 18, 2026
Stock price -- (DNLI: $17.99 vs. PTGX: $81.99)
Brand notoriety: DNLI and PTGX are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: DNLI: 89% vs. PTGX: 72%
Market capitalization -- DNLI: $2.81B vs. PTGX: $5.13B
DNLI [@Biotechnology] is valued at $2.81B. PTGX’s [@Biotechnology] market capitalization is $5.13B. The market cap for tickers in the [@Biotechnology] industry ranges from $111.98B to $0. The average market capitalization across the [@Biotechnology] industry is $2.25B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

DNLI’s FA Score shows that 0 FA rating(s) are green whilePTGX’s FA Score has 1 green FA rating(s).

  • DNLI’s FA Score: 0 green, 5 red.
  • PTGX’s FA Score: 1 green, 4 red.
According to our system of comparison, PTGX is a better buy in the long-term than DNLI.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

DNLI’s TA Score shows that 5 TA indicator(s) are bullish while PTGX’s TA Score has 4 bullish TA indicator(s).

  • DNLI’s TA Score: 5 bullish, 4 bearish.
  • PTGX’s TA Score: 4 bullish, 6 bearish.
According to our system of comparison, DNLI is a better buy in the short-term than PTGX.

Price Growth

DNLI (@Biotechnology) experienced а +5.33% price change this week, while PTGX (@Biotechnology) price change was +2.21% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.24%. For the same industry, the average monthly price growth was +4.14%, and the average quarterly price growth was +42.40%.

Reported Earning Dates

DNLI is expected to report earnings on Mar 02, 2026.

PTGX is expected to report earnings on Mar 18, 2026.

Industries' Descriptions

@Biotechnology (+1.24% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
PTGX($5.13B) has a higher market cap than DNLI($2.81B). DNLI YTD gains are higher at: 8.964 vs. PTGX (-6.125). PTGX has higher annual earnings (EBITDA): 21.7M vs. DNLI (-534.17M). DNLI has more cash in the bank: 848M vs. PTGX (576M). PTGX has less debt than DNLI: PTGX (10.7M) vs DNLI (44.4M). PTGX has higher revenues than DNLI: PTGX (209M) vs DNLI (0).
DNLIPTGXDNLI / PTGX
Capitalization2.81B5.13B55%
EBITDA-534.17M21.7M-2,462%
Gain YTD8.964-6.125-146%
P/E RatioN/A124.23-
Revenue0209M-
Total Cash848M576M147%
Total Debt44.4M10.7M415%
FUNDAMENTALS RATINGS
DNLI vs PTGX: Fundamental Ratings
DNLI
PTGX
OUTLOOK RATING
1..100
1463
VALUATION
overvalued / fair valued / undervalued
1..100
93
Overvalued
92
Overvalued
PROFIT vs RISK RATING
1..100
10035
SMR RATING
1..100
9767
PRICE GROWTH RATING
1..100
4641
P/E GROWTH RATING
1..100
992
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

PTGX's Valuation (92) in the Biotechnology industry is in the same range as DNLI (93). This means that PTGX’s stock grew similarly to DNLI’s over the last 12 months.

PTGX's Profit vs Risk Rating (35) in the Biotechnology industry is somewhat better than the same rating for DNLI (100). This means that PTGX’s stock grew somewhat faster than DNLI’s over the last 12 months.

PTGX's SMR Rating (67) in the Biotechnology industry is in the same range as DNLI (97). This means that PTGX’s stock grew similarly to DNLI’s over the last 12 months.

PTGX's Price Growth Rating (41) in the Biotechnology industry is in the same range as DNLI (46). This means that PTGX’s stock grew similarly to DNLI’s over the last 12 months.

PTGX's P/E Growth Rating (2) in the Biotechnology industry is significantly better than the same rating for DNLI (99). This means that PTGX’s stock grew significantly faster than DNLI’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
DNLIPTGX
RSI
ODDS (%)
N/A
Bullish Trend 2 days ago
65%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
81%
Momentum
ODDS (%)
Bullish Trend 2 days ago
74%
Bearish Trend 2 days ago
72%
MACD
ODDS (%)
Bullish Trend 2 days ago
80%
Bearish Trend 2 days ago
77%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
77%
Bullish Trend 2 days ago
80%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
73%
Bearish Trend 2 days ago
80%
Advances
ODDS (%)
Bullish Trend 3 days ago
76%
Bullish Trend 4 days ago
78%
Declines
ODDS (%)
Bearish Trend 13 days ago
82%
Bearish Trend 2 days ago
74%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
81%
Bullish Trend 2 days ago
86%
Aroon
ODDS (%)
Bearish Trend 2 days ago
82%
Bearish Trend 2 days ago
82%
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DNLI
Daily Signal:
Gain/Loss:
PTGX
Daily Signal:
Gain/Loss:
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PTGX and

Correlation & Price change

A.I.dvisor indicates that over the last year, PTGX has been loosely correlated with BIESF. These tickers have moved in lockstep 61% of the time. This A.I.-generated data suggests there is some statistical probability that if PTGX jumps, then BIESF could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To PTGX
1D Price
Change %
PTGX100%
-3.26%
BIESF - PTGX
61%
Loosely correlated
N/A
TRVI - PTGX
44%
Loosely correlated
-2.60%
DNLI - PTGX
41%
Loosely correlated
-4.21%
ORMP - PTGX
37%
Loosely correlated
+6.98%
MLYS - PTGX
37%
Loosely correlated
+4.33%
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