CSTL
Price
$19.25
Change
-$0.11 (-0.57%)
Updated
Aug 11, 01:06 PM (EDT)
Capitalization
561.6M
91 days until earnings call
TWST
Price
$27.32
Change
+$1.68 (+6.55%)
Updated
Aug 11, 03:46 PM (EDT)
Capitalization
1.55B
105 days until earnings call
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CSTL vs TWST

Header iconCSTL vs TWST Comparison
Open Charts CSTL vs TWSTBanner chart's image
Castle Biosciences
Price$19.25
Change-$0.11 (-0.57%)
Volume$300
Capitalization561.6M
Twist Bioscience
Price$27.32
Change+$1.68 (+6.55%)
Volume$746
Capitalization1.55B
CSTL vs TWST Comparison Chart in %
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CSTL
Daily Signalchanged days ago
Gain/Loss if bought
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TWST
Daily Signalchanged days ago
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CSTL vs. TWST commentary
Aug 11, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CSTL is a StrongBuy and TWST is a Hold.

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COMPARISON
Comparison
Aug 11, 2025
Stock price -- (CSTL: $19.36 vs. TWST: $25.64)
Brand notoriety: CSTL and TWST are both not notable
Both companies represent the Medical Specialties industry
Current volume relative to the 65-day Moving Average: CSTL: 115% vs. TWST: 163%
Market capitalization -- CSTL: $561.6M vs. TWST: $1.55B
CSTL [@Medical Specialties] is valued at $561.6M. TWST’s [@Medical Specialties] market capitalization is $1.55B. The market cap for tickers in the [@Medical Specialties] industry ranges from $3.82T to $0. The average market capitalization across the [@Medical Specialties] industry is $9.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CSTL’s FA Score shows that 0 FA rating(s) are green whileTWST’s FA Score has 0 green FA rating(s).

  • CSTL’s FA Score: 0 green, 5 red.
  • TWST’s FA Score: 0 green, 5 red.
According to our system of comparison, TWST is a better buy in the long-term than CSTL.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

CSTL’s TA Score shows that 4 TA indicator(s) are bullish while TWST’s TA Score has 4 bullish TA indicator(s).

  • CSTL’s TA Score: 4 bullish, 5 bearish.
  • TWST’s TA Score: 4 bullish, 6 bearish.
According to our system of comparison, CSTL is a better buy in the short-term than TWST.

Price Growth

CSTL (@Medical Specialties) experienced а +32.15% price change this week, while TWST (@Medical Specialties) price change was -23.87% for the same time period.

The average weekly price growth across all stocks in the @Medical Specialties industry was +3.92%. For the same industry, the average monthly price growth was +1.56%, and the average quarterly price growth was -1.80%.

Reported Earning Dates

CSTL is expected to report earnings on Nov 10, 2025.

TWST is expected to report earnings on Nov 24, 2025.

Industries' Descriptions

@Medical Specialties (+3.92% weekly)

Medical specialties are companies that make equipment used by the health care industry. Equipment manufactured and distributed by these companies include dialysis machines, blood analysis equipment, surgical equipment, dental instruments, and diagnostic tools, among other items. Large companies typically aim to produce and distribute high-quality products across a broad market spectrum. Smaller firms are more likely to specialize in a particular market segment. Due to the industry’s close association with medical treatments, they typically have low sensitivity to macroeconomic fluctuations. Within this industry, Abbott Laboratories, Medtronic Plc and Thermo Fisher Scientific Inc. are some of the companies with multi-billion market capitalizations in the U.S. stock markets.

SUMMARIES
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FUNDAMENTALS
Fundamentals
TWST($1.55B) has a higher market cap than CSTL($562M). CSTL YTD gains are higher at: -27.355 vs. TWST (-44.825). CSTL has higher annual earnings (EBITDA): 40.8M vs. TWST (-162.85M). CSTL has more cash in the bank: 275M vs. TWST (257M). CSTL has less debt than TWST: CSTL (25.8M) vs TWST (80.3M). TWST (348M) and CSTL (347M) have equivalent revenues.
CSTLTWSTCSTL / TWST
Capitalization562M1.55B36%
EBITDA40.8M-162.85M-25%
Gain YTD-27.355-44.82561%
P/E Ratio30.24N/A-
Revenue347M348M100%
Total Cash275M257M107%
Total Debt25.8M80.3M32%
FUNDAMENTALS RATINGS
CSTL vs TWST: Fundamental Ratings
CSTL
TWST
OUTLOOK RATING
1..100
5050
VALUATION
overvalued / fair valued / undervalued
1..100
55
Fair valued
40
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9197
PRICE GROWTH RATING
1..100
6293
P/E GROWTH RATING
1..100
100100
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TWST's Valuation (40) in the Biotechnology industry is in the same range as CSTL (55) in the null industry. This means that TWST’s stock grew similarly to CSTL’s over the last 12 months.

TWST's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as CSTL (100) in the null industry. This means that TWST’s stock grew similarly to CSTL’s over the last 12 months.

CSTL's SMR Rating (91) in the null industry is in the same range as TWST (97) in the Biotechnology industry. This means that CSTL’s stock grew similarly to TWST’s over the last 12 months.

CSTL's Price Growth Rating (62) in the null industry is in the same range as TWST (93) in the Biotechnology industry. This means that CSTL’s stock grew similarly to TWST’s over the last 12 months.

CSTL's P/E Growth Rating (100) in the null industry is in the same range as TWST (100) in the Biotechnology industry. This means that CSTL’s stock grew similarly to TWST’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
CSTLTWST
RSI
ODDS (%)
Bullish Trend 4 days ago
90%
Bullish Trend 4 days ago
90%
Stochastic
ODDS (%)
Bearish Trend 4 days ago
77%
Bullish Trend 4 days ago
90%
Momentum
ODDS (%)
Bullish Trend 4 days ago
80%
Bearish Trend 4 days ago
84%
MACD
ODDS (%)
Bullish Trend 4 days ago
79%
Bearish Trend 4 days ago
89%
TrendWeek
ODDS (%)
Bullish Trend 4 days ago
81%
Bearish Trend 4 days ago
88%
TrendMonth
ODDS (%)
Bearish Trend 4 days ago
81%
Bearish Trend 4 days ago
86%
Advances
ODDS (%)
N/A
Bullish Trend 15 days ago
78%
Declines
ODDS (%)
Bearish Trend 4 days ago
85%
Bearish Trend 5 days ago
89%
BollingerBands
ODDS (%)
Bearish Trend 4 days ago
85%
Bullish Trend 4 days ago
80%
Aroon
ODDS (%)
Bearish Trend 4 days ago
81%
Bearish Trend 4 days ago
86%
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CSTL
Daily Signalchanged days ago
Gain/Loss if bought
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TWST
Daily Signalchanged days ago
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CSTL and

Correlation & Price change

A.I.dvisor indicates that over the last year, CSTL has been loosely correlated with IMTH. These tickers have moved in lockstep 41% of the time. This A.I.-generated data suggests there is some statistical probability that if CSTL jumps, then IMTH could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CSTL
1D Price
Change %
CSTL100%
-1.48%
IMTH - CSTL
41%
Loosely correlated
+0.07%
VCYT - CSTL
39%
Loosely correlated
-1.12%
NTRA - CSTL
38%
Loosely correlated
+7.70%
GH - CSTL
38%
Loosely correlated
+7.62%
TWST - CSTL
38%
Loosely correlated
+2.56%
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