CRL
Price
$184.67
Change
+$9.91 (+5.67%)
Updated
Dec 3 closing price
Capitalization
9.09B
76 days until earnings call
Intraday BUY SELL Signals
OPK
Price
$1.37
Change
+$0.04 (+3.01%)
Updated
Dec 3 closing price
Capitalization
1.05B
77 days until earnings call
Intraday BUY SELL Signals
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CRL vs OPK

Header iconCRL vs OPK Comparison
Open Charts CRL vs OPKBanner chart's image
Charles River Laboratories International
Price$184.67
Change+$9.91 (+5.67%)
Volume$770.52K
Capitalization9.09B
OPKO Health
Price$1.37
Change+$0.04 (+3.01%)
Volume$2.99M
Capitalization1.05B
CRL vs OPK Comparison Chart in %
CRL
Daily Signal:
Gain/Loss:
OPK
Daily Signal:
Gain/Loss:
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VS
CRL vs. OPK commentary
Dec 04, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CRL is a StrongBuy and OPK is a Hold.

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COMPARISON
Comparison
Dec 04, 2025
Stock price -- (CRL: $174.80 vs. OPK: $1.34)
Brand notoriety: CRL and OPK are both not notable
Both companies represent the Medical Specialties industry
Current volume relative to the 65-day Moving Average: CRL: 16% vs. OPK: 75%
Market capitalization -- CRL: $9.09B vs. OPK: $1.05B
CRL [@Medical Specialties] is valued at $9.09B. OPK’s [@Medical Specialties] market capitalization is $1.05B. The market cap for tickers in the [@Medical Specialties] industry ranges from $3.82T to $0. The average market capitalization across the [@Medical Specialties] industry is $12.57B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CRL’s FA Score shows that 1 FA rating(s) are green whileOPK’s FA Score has 0 green FA rating(s).

  • CRL’s FA Score: 1 green, 4 red.
  • OPK’s FA Score: 0 green, 5 red.
According to our system of comparison, CRL is a better buy in the long-term than OPK.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

CRL’s TA Score shows that 4 TA indicator(s) are bullish while OPK’s TA Score has 5 bullish TA indicator(s).

  • CRL’s TA Score: 4 bullish, 6 bearish.
  • OPK’s TA Score: 5 bullish, 5 bearish.
According to our system of comparison, OPK is a better buy in the short-term than CRL.

Price Growth

CRL (@Medical Specialties) experienced а -1.83% price change this week, while OPK (@Medical Specialties) price change was -1.11% for the same time period.

The average weekly price growth across all stocks in the @Medical Specialties industry was -0.29%. For the same industry, the average monthly price growth was +2.65%, and the average quarterly price growth was +28.81%.

Reported Earning Dates

CRL is expected to report earnings on Feb 18, 2026.

OPK is expected to report earnings on Feb 19, 2026.

Industries' Descriptions

@Medical Specialties (-0.29% weekly)

Medical specialties are companies that make equipment used by the health care industry. Equipment manufactured and distributed by these companies include dialysis machines, blood analysis equipment, surgical equipment, dental instruments, and diagnostic tools, among other items. Large companies typically aim to produce and distribute high-quality products across a broad market spectrum. Smaller firms are more likely to specialize in a particular market segment. Due to the industry’s close association with medical treatments, they typically have low sensitivity to macroeconomic fluctuations. Within this industry, Abbott Laboratories, Medtronic Plc and Thermo Fisher Scientific Inc. are some of the companies with multi-billion market capitalizations in the U.S. stock markets.

SUMMARIES
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FUNDAMENTALS
Fundamentals
CRL($9.09B) has a higher market cap than OPK($1.05B). CRL YTD gains are higher at: -5.309 vs. OPK (-9.184). CRL has higher annual earnings (EBITDA): 528M vs. OPK (59.6M). OPK has more cash in the bank: 272M vs. CRL (183M). OPK has less debt than CRL: OPK (396M) vs CRL (2.79B). CRL has higher revenues than OPK: CRL (4.03B) vs OPK (664M).
CRLOPKCRL / OPK
Capitalization9.09B1.05B864%
EBITDA528M59.6M886%
Gain YTD-5.309-9.18458%
P/E Ratio577.05N/A-
Revenue4.03B664M607%
Total Cash183M272M67%
Total Debt2.79B396M704%
FUNDAMENTALS RATINGS
CRL vs OPK: Fundamental Ratings
CRL
OPK
OUTLOOK RATING
1..100
5050
VALUATION
overvalued / fair valued / undervalued
1..100
91
Overvalued
58
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9194
PRICE GROWTH RATING
1..100
4973
P/E GROWTH RATING
1..100
198
SEASONALITY SCORE
1..100
5022

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

OPK's Valuation (58) in the Biotechnology industry is somewhat better than the same rating for CRL (91) in the Miscellaneous Commercial Services industry. This means that OPK’s stock grew somewhat faster than CRL’s over the last 12 months.

OPK's Profit vs Risk Rating (100) in the Biotechnology industry is in the same range as CRL (100) in the Miscellaneous Commercial Services industry. This means that OPK’s stock grew similarly to CRL’s over the last 12 months.

CRL's SMR Rating (91) in the Miscellaneous Commercial Services industry is in the same range as OPK (94) in the Biotechnology industry. This means that CRL’s stock grew similarly to OPK’s over the last 12 months.

CRL's Price Growth Rating (49) in the Miscellaneous Commercial Services industry is in the same range as OPK (73) in the Biotechnology industry. This means that CRL’s stock grew similarly to OPK’s over the last 12 months.

CRL's P/E Growth Rating (1) in the Miscellaneous Commercial Services industry is significantly better than the same rating for OPK (98) in the Biotechnology industry. This means that CRL’s stock grew significantly faster than OPK’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
CRLOPK
RSI
ODDS (%)
Bearish Trend 7 days ago
62%
Bullish Trend 7 days ago
75%
Stochastic
ODDS (%)
Bearish Trend 7 days ago
84%
Bearish Trend 7 days ago
77%
Momentum
ODDS (%)
Bullish Trend 7 days ago
65%
Bullish Trend 7 days ago
76%
MACD
ODDS (%)
Bullish Trend 7 days ago
65%
Bullish Trend 7 days ago
78%
TrendWeek
ODDS (%)
Bullish Trend 7 days ago
69%
Bullish Trend 7 days ago
74%
TrendMonth
ODDS (%)
Bearish Trend 7 days ago
73%
Bearish Trend 7 days ago
77%
Advances
ODDS (%)
Bullish Trend 9 days ago
70%
Bullish Trend 16 days ago
74%
Declines
ODDS (%)
Bearish Trend 16 days ago
69%
Bearish Trend 22 days ago
79%
BollingerBands
ODDS (%)
Bearish Trend 7 days ago
76%
Bullish Trend 7 days ago
82%
Aroon
ODDS (%)
Bearish Trend 7 days ago
75%
Bearish Trend 7 days ago
83%
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CRL
Daily Signal:
Gain/Loss:
OPK
Daily Signal:
Gain/Loss:
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CRL and

Correlation & Price change

A.I.dvisor indicates that over the last year, CRL has been closely correlated with IQV. These tickers have moved in lockstep 73% of the time. This A.I.-generated data suggests there is a high statistical probability that if CRL jumps, then IQV could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CRL
1D Price
Change %
CRL100%
-0.73%
IQV - CRL
73%
Closely correlated
-1.23%
A - CRL
65%
Loosely correlated
-0.85%
RVTY - CRL
65%
Loosely correlated
+0.33%
MTD - CRL
63%
Loosely correlated
-1.48%
DHR - CRL
58%
Loosely correlated
+1.11%
More

OPK and

Correlation & Price change

A.I.dvisor indicates that over the last year, OPK has been loosely correlated with ICUI. These tickers have moved in lockstep 41% of the time. This A.I.-generated data suggests there is some statistical probability that if OPK jumps, then ICUI could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To OPK
1D Price
Change %
OPK100%
+1.14%
ICUI - OPK
41%
Loosely correlated
+0.21%
CLPT - OPK
39%
Loosely correlated
-2.98%
CRL - OPK
36%
Loosely correlated
-0.73%
UTMD - OPK
36%
Loosely correlated
+0.20%
NOTV - OPK
35%
Loosely correlated
-2.28%
More