CRBU
Price
$2.13
Change
+$0.20 (+10.36%)
Updated
Sep 26 closing price
Capitalization
198.35M
45 days until earnings call
SYRE
Price
$16.24
Change
+$0.63 (+4.04%)
Updated
Sep 26 closing price
Capitalization
980.91M
40 days until earnings call
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CRBU vs SYRE

Header iconCRBU vs SYRE Comparison
Open Charts CRBU vs SYREBanner chart's image
Caribou Biosciences
Price$2.13
Change+$0.20 (+10.36%)
Volume$1.59M
Capitalization198.35M
Spyre Therapeutics
Price$16.24
Change+$0.63 (+4.04%)
Volume$985.41K
Capitalization980.91M
CRBU vs SYRE Comparison Chart in %
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CRBU
Daily Signalchanged days ago
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SYRE
Daily Signalchanged days ago
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CRBU vs. SYRE commentary
Sep 28, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CRBU is a Hold and SYRE is a Buy.

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COMPARISON
Comparison
Sep 28, 2025
Stock price -- (CRBU: $2.13 vs. SYRE: $16.24)
Brand notoriety: CRBU and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: CRBU: 140% vs. SYRE: 176%
Market capitalization -- CRBU: $198.35M vs. SYRE: $980.91M
CRBU [@Biotechnology] is valued at $198.35M. SYRE’s [@Biotechnology] market capitalization is $980.91M. The market cap for tickers in the [@Biotechnology] industry ranges from $98.9B to $0. The average market capitalization across the [@Biotechnology] industry is $1.9B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CRBU’s FA Score shows that 1 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • CRBU’s FA Score: 1 green, 4 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, CRBU is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

CRBU’s TA Score shows that 4 TA indicator(s) are bullish while SYRE’s TA Score has 6 bullish TA indicator(s).

  • CRBU’s TA Score: 4 bullish, 5 bearish.
  • SYRE’s TA Score: 6 bullish, 4 bearish.
According to our system of comparison, SYRE is a better buy in the short-term than CRBU.

Price Growth

CRBU (@Biotechnology) experienced а +26.04% price change this week, while SYRE (@Biotechnology) price change was +9.14% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.00%. For the same industry, the average monthly price growth was +9.18%, and the average quarterly price growth was +54.60%.

Reported Earning Dates

CRBU is expected to report earnings on Nov 11, 2025.

SYRE is expected to report earnings on Nov 06, 2025.

Industries' Descriptions

@Biotechnology (+4.00% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($981M) has a higher market cap than CRBU($198M). CRBU YTD gains are higher at: 33.962 vs. SYRE (-30.241). CRBU has higher annual earnings (EBITDA): -150.76M vs. SYRE (-222.15M). SYRE has more cash in the bank: 527M vs. CRBU (184M). SYRE has less debt than CRBU: SYRE (0) vs CRBU (25.9M). CRBU has higher revenues than SYRE: CRBU (9.12M) vs SYRE (0).
CRBUSYRECRBU / SYRE
Capitalization198M981M20%
EBITDA-150.76M-222.15M68%
Gain YTD33.962-30.241-112%
P/E RatioN/A1.68-
Revenue9.12M0-
Total Cash184M527M35%
Total Debt25.9M0-
FUNDAMENTALS RATINGS
SYRE: Fundamental Ratings
SYRE
OUTLOOK RATING
1..100
11
VALUATION
overvalued / fair valued / undervalued
1..100
67
Overvalued
PROFIT vs RISK RATING
1..100
100
SMR RATING
1..100
98
PRICE GROWTH RATING
1..100
64
P/E GROWTH RATING
1..100
82
SEASONALITY SCORE
1..100
34

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TECHNICAL ANALYSIS
Technical Analysis
CRBUSYRE
RSI
ODDS (%)
N/A
Bullish Trend 2 days ago
89%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
89%
Bullish Trend 2 days ago
84%
Momentum
ODDS (%)
Bullish Trend 2 days ago
69%
Bullish Trend 2 days ago
84%
MACD
ODDS (%)
Bullish Trend 2 days ago
81%
Bullish Trend 2 days ago
87%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
79%
Bullish Trend 2 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
82%
Bearish Trend 2 days ago
89%
Advances
ODDS (%)
Bullish Trend 25 days ago
79%
Bullish Trend 4 days ago
84%
Declines
ODDS (%)
Bearish Trend 11 days ago
89%
Bearish Trend 12 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
78%
Bullish Trend 2 days ago
83%
Aroon
ODDS (%)
Bearish Trend 4 days ago
90%
Bearish Trend 2 days ago
89%
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CRBU
Daily Signalchanged days ago
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SYRE
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CRBU and

Correlation & Price change

A.I.dvisor indicates that over the last year, CRBU has been loosely correlated with CRSP. These tickers have moved in lockstep 57% of the time. This A.I.-generated data suggests there is some statistical probability that if CRBU jumps, then CRSP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CRBU
1D Price
Change %
CRBU100%
+10.36%
CRSP - CRBU
57%
Loosely correlated
+2.24%
FATE - CRBU
52%
Loosely correlated
+3.01%
MGNX - CRBU
52%
Loosely correlated
+4.85%
BEAM - CRBU
51%
Loosely correlated
-0.52%
SYRE - CRBU
50%
Loosely correlated
+4.04%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with CGON. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then CGON could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+4.04%
CGON - SYRE
58%
Loosely correlated
+2.91%
IDYA - SYRE
58%
Loosely correlated
+4.44%
VRDN - SYRE
58%
Loosely correlated
+5.82%
XNCR - SYRE
57%
Loosely correlated
+12.00%
CRNX - SYRE
56%
Loosely correlated
+27.92%
More