CPRX
Price
$23.09
Change
+$0.47 (+2.08%)
Updated
Dec 3, 04:59 PM (EDT)
Capitalization
2.79B
105 days until earnings call
Intraday BUY SELL Signals
SYRE
Price
$32.20
Change
+$3.80 (+13.38%)
Updated
Dec 3, 04:59 PM (EDT)
Capitalization
2.22B
84 days until earnings call
Intraday BUY SELL Signals
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CPRX vs SYRE

Header iconCPRX vs SYRE Comparison
Open Charts CPRX vs SYREBanner chart's image
Catalyst Pharmaceuticals
Price$23.09
Change+$0.47 (+2.08%)
Volume$22.45K
Capitalization2.79B
Spyre Therapeutics
Price$32.20
Change+$3.80 (+13.38%)
Volume$57.92K
Capitalization2.22B
CPRX vs SYRE Comparison Chart in %
CPRX
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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VS
CPRX vs. SYRE commentary
Dec 04, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CPRX is a Buy and SYRE is a Hold.

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COMPARISON
Comparison
Dec 04, 2025
Stock price -- (CPRX: $22.61 vs. SYRE: $28.40)
Brand notoriety: CPRX and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: CPRX: 30% vs. SYRE: 23%
Market capitalization -- CPRX: $2.79B vs. SYRE: $2.22B
CPRX [@Biotechnology] is valued at $2.79B. SYRE’s [@Biotechnology] market capitalization is $2.22B. The market cap for tickers in the [@Biotechnology] industry ranges from $107.98B to $0. The average market capitalization across the [@Biotechnology] industry is $2.19B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CPRX’s FA Score shows that 2 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • CPRX’s FA Score: 2 green, 3 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, CPRX is a better buy in the long-term than SYRE.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

CPRX’s TA Score shows that 4 TA indicator(s) are bullish while SYRE’s TA Score has 4 bullish TA indicator(s).

  • CPRX’s TA Score: 4 bullish, 4 bearish.
  • SYRE’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, both CPRX and SYRE are a good buy in the short-term.

Price Growth

CPRX (@Biotechnology) experienced а -4.15% price change this week, while SYRE (@Biotechnology) price change was -2.74% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.32%. For the same industry, the average monthly price growth was +1.23%, and the average quarterly price growth was +54.93%.

Reported Earning Dates

CPRX is expected to report earnings on Mar 18, 2026.

SYRE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+0.32% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
CPRX($2.79B) has a higher market cap than SYRE($2.22B). CPRX has higher P/E ratio than SYRE: CPRX (13.27) vs SYRE (1.72). SYRE YTD gains are higher at: 21.993 vs. CPRX (8.337). CPRX has higher annual earnings (EBITDA): 281M vs. SYRE (-222.15M). CPRX has more cash in the bank: 653M vs. SYRE (527M). SYRE has less debt than CPRX: SYRE (0) vs CPRX (2.99M). CPRX has higher revenues than SYRE: CPRX (558M) vs SYRE (0).
CPRXSYRECPRX / SYRE
Capitalization2.79B2.22B126%
EBITDA281M-222.15M-126%
Gain YTD8.33721.99338%
P/E Ratio13.271.72773%
Revenue558M0-
Total Cash653M527M124%
Total Debt2.99M0-
FUNDAMENTALS RATINGS
CPRX vs SYRE: Fundamental Ratings
CPRX
SYRE
OUTLOOK RATING
1..100
5050
VALUATION
overvalued / fair valued / undervalued
1..100
63
Fair valued
69
Overvalued
PROFIT vs RISK RATING
1..100
20100
SMR RATING
1..100
3397
PRICE GROWTH RATING
1..100
4836
P/E GROWTH RATING
1..100
7674
SEASONALITY SCORE
1..100
n/an/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

CPRX's Valuation (63) in the Pharmaceuticals Other industry is in the same range as SYRE (69) in the Pharmaceuticals Major industry. This means that CPRX’s stock grew similarly to SYRE’s over the last 12 months.

CPRX's Profit vs Risk Rating (20) in the Pharmaceuticals Other industry is significantly better than the same rating for SYRE (100) in the Pharmaceuticals Major industry. This means that CPRX’s stock grew significantly faster than SYRE’s over the last 12 months.

CPRX's SMR Rating (33) in the Pharmaceuticals Other industry is somewhat better than the same rating for SYRE (97) in the Pharmaceuticals Major industry. This means that CPRX’s stock grew somewhat faster than SYRE’s over the last 12 months.

SYRE's Price Growth Rating (36) in the Pharmaceuticals Major industry is in the same range as CPRX (48) in the Pharmaceuticals Other industry. This means that SYRE’s stock grew similarly to CPRX’s over the last 12 months.

SYRE's P/E Growth Rating (74) in the Pharmaceuticals Major industry is in the same range as CPRX (76) in the Pharmaceuticals Other industry. This means that SYRE’s stock grew similarly to CPRX’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
CPRXSYRE
RSI
ODDS (%)
Bearish Trend 6 days ago
87%
Bearish Trend 6 days ago
90%
Stochastic
ODDS (%)
Bearish Trend 6 days ago
77%
Bearish Trend 6 days ago
88%
Momentum
ODDS (%)
Bullish Trend 6 days ago
86%
Bullish Trend 6 days ago
87%
MACD
ODDS (%)
Bullish Trend 6 days ago
85%
Bullish Trend 6 days ago
80%
TrendWeek
ODDS (%)
Bullish Trend 6 days ago
82%
Bullish Trend 6 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 6 days ago
81%
Bullish Trend 6 days ago
83%
Advances
ODDS (%)
Bullish Trend 9 days ago
80%
Bullish Trend 6 days ago
85%
Declines
ODDS (%)
Bearish Trend 6 days ago
67%
Bearish Trend 28 days ago
90%
BollingerBands
ODDS (%)
Bearish Trend 6 days ago
72%
Bearish Trend 6 days ago
90%
Aroon
ODDS (%)
Bullish Trend 6 days ago
83%
Bullish Trend 6 days ago
82%
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CPRX
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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CPRX and

Correlation & Price change

A.I.dvisor indicates that over the last year, CPRX has been loosely correlated with VIR. These tickers have moved in lockstep 50% of the time. This A.I.-generated data suggests there is some statistical probability that if CPRX jumps, then VIR could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CPRX
1D Price
Change %
CPRX100%
-0.35%
VIR - CPRX
50%
Loosely correlated
-7.17%
SANA - CPRX
48%
Loosely correlated
-0.88%
IRON - CPRX
43%
Loosely correlated
-2.16%
ADMA - CPRX
41%
Loosely correlated
-0.62%
SYRE - CPRX
41%
Loosely correlated
-0.91%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with APGE. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then APGE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
-0.91%
APGE - SYRE
58%
Loosely correlated
+0.20%
CGON - SYRE
58%
Loosely correlated
-4.35%
RGNX - SYRE
57%
Loosely correlated
-3.10%
IDYA - SYRE
57%
Loosely correlated
-1.75%
ORKA - SYRE
56%
Loosely correlated
+0.56%
More