CLGN
Price
$1.86
Change
-$0.07 (-3.61%)
Updated
Jun 9, 02:14 PM (EDT)
Capitalization
22.22M
73 days until earnings call
SPRO
Price
$2.50
Change
-$0.06 (-2.34%)
Updated
Jun 6 closing price
Capitalization
139.78M
59 days until earnings call
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CLGN vs SPRO

Header iconCLGN vs SPRO Comparison
Open Charts CLGN vs SPROBanner chart's image
CollPlant Biotechnologies
Price$1.86
Change-$0.07 (-3.61%)
Volume$100
Capitalization22.22M
Spero Therapeutics
Price$2.50
Change-$0.06 (-2.34%)
Volume$2.55M
Capitalization139.78M
CLGN vs SPRO Comparison Chart
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SPRO
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Gain/Loss if bought
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CLGN vs. SPRO commentary
Jun 09, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CLGN is a Hold and SPRO is a Buy.

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COMPARISON
Comparison
Jun 09, 2025
Stock price -- (CLGN: $3.40 vs. SPRO: $2.35)
Brand notoriety: CLGN and SPRO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: CLGN: 3170% vs. SPRO: 4440%
Market capitalization -- CLGN: $22.22M vs. SPRO: $139.78M
CLGN [@Biotechnology] is valued at $22.22M. SPRO’s [@Biotechnology] market capitalization is $139.78M. The market cap for tickers in the [@Biotechnology] industry ranges from $334.5B to $0. The average market capitalization across the [@Biotechnology] industry is $2.25B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CLGN’s FA Score shows that 1 FA rating(s) are green whileSPRO’s FA Score has 1 green FA rating(s).

  • CLGN’s FA Score: 1 green, 4 red.
  • SPRO’s FA Score: 1 green, 4 red.
According to our system of comparison, SPRO is a better buy in the long-term than CLGN.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

SPRO’s TA Score shows that 5 TA indicator(s) are bullish.

  • SPRO’s TA Score: 5 bullish, 4 bearish.

Price Growth

CLGN (@Biotechnology) experienced а +66.67% price change this week, while SPRO (@Biotechnology) price change was +242.67% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.11%. For the same industry, the average monthly price growth was +10.01%, and the average quarterly price growth was -2.16%.

Reported Earning Dates

CLGN is expected to report earnings on Aug 21, 2025.

SPRO is expected to report earnings on Aug 07, 2025.

Industries' Descriptions

@Biotechnology (+4.11% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SPRO($140M) has a higher market cap than CLGN($22.2M). SPRO YTD gains are higher at: 128.155 vs. CLGN (-5.556). SPRO has higher annual earnings (EBITDA): -2.45M vs. CLGN (-17.27M). SPRO has more cash in the bank: 76.3M vs. CLGN (15.4M). CLGN has less debt than SPRO: CLGN (3.25M) vs SPRO (4.62M). SPRO has higher revenues than CLGN: SPRO (89.9M) vs CLGN (650K).
CLGNSPROCLGN / SPRO
Capitalization22.2M140M16%
EBITDA-17.27M-2.45M706%
Gain YTD-5.556128.155-4%
P/E RatioN/A10.75-
Revenue650K89.9M1%
Total Cash15.4M76.3M20%
Total Debt3.25M4.62M70%
FUNDAMENTALS RATINGS
CLGN vs SPRO: Fundamental Ratings
CLGN
SPRO
OUTLOOK RATING
1..100
3539
VALUATION
overvalued / fair valued / undervalued
1..100
94
Overvalued
57
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9879
PRICE GROWTH RATING
1..100
9386
P/E GROWTH RATING
1..100
14
SEASONALITY SCORE
1..100
50n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SPRO's Valuation (57) in the Pharmaceuticals Major industry is somewhat better than the same rating for CLGN (94) in the Biotechnology industry. This means that SPRO’s stock grew somewhat faster than CLGN’s over the last 12 months.

SPRO's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as CLGN (100) in the Biotechnology industry. This means that SPRO’s stock grew similarly to CLGN’s over the last 12 months.

SPRO's SMR Rating (79) in the Pharmaceuticals Major industry is in the same range as CLGN (98) in the Biotechnology industry. This means that SPRO’s stock grew similarly to CLGN’s over the last 12 months.

SPRO's Price Growth Rating (86) in the Pharmaceuticals Major industry is in the same range as CLGN (93) in the Biotechnology industry. This means that SPRO’s stock grew similarly to CLGN’s over the last 12 months.

CLGN's P/E Growth Rating (1) in the Biotechnology industry is in the same range as SPRO (4) in the Pharmaceuticals Major industry. This means that CLGN’s stock grew similarly to SPRO’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
SPRO
RSI
ODDS (%)
Bearish Trend 13 days ago
79%
Stochastic
ODDS (%)
Bearish Trend 13 days ago
79%
Momentum
ODDS (%)
Bullish Trend 13 days ago
67%
MACD
ODDS (%)
Bullish Trend 13 days ago
80%
TrendWeek
ODDS (%)
Bullish Trend 13 days ago
73%
TrendMonth
ODDS (%)
Bullish Trend 13 days ago
75%
Advances
ODDS (%)
Bullish Trend 19 days ago
72%
Declines
ODDS (%)
Bearish Trend about 1 month ago
90%
BollingerBands
ODDS (%)
Bearish Trend 13 days ago
82%
Aroon
ODDS (%)
N/A
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SPRO
Daily Signalchanged days ago
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CLGN and

Correlation & Price change

A.I.dvisor indicates that over the last year, CLGN has been closely correlated with SPRO. These tickers have moved in lockstep 66% of the time. This A.I.-generated data suggests there is a high statistical probability that if CLGN jumps, then SPRO could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CLGN
1D Price
Change %
CLGN100%
+76.17%
SPRO - CLGN
66%
Closely correlated
+244.57%
ASBP - CLGN
46%
Loosely correlated
+197.43%
CLLS - CLGN
33%
Poorly correlated
-3.42%
CVM - CLGN
24%
Poorly correlated
-0.40%
ANNX - CLGN
22%
Poorly correlated
+3.05%
More

SPRO and

Correlation & Price change

A.I.dvisor indicates that over the last year, SPRO has been closely correlated with CLGN. These tickers have moved in lockstep 66% of the time. This A.I.-generated data suggests there is a high statistical probability that if SPRO jumps, then CLGN could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SPRO
1D Price
Change %
SPRO100%
+244.57%
CLGN - SPRO
66%
Closely correlated
+76.17%
ASBP - SPRO
62%
Loosely correlated
+197.43%
ITOS - SPRO
35%
Loosely correlated
+17.94%
XENE - SPRO
32%
Poorly correlated
-3.29%
SYRE - SPRO
31%
Poorly correlated
+0.60%
More