CLGN
Price
$1.62
Change
-$0.06 (-3.57%)
Updated
Feb 4, 03:11 PM (EDT)
Capitalization
21.08M
56 days until earnings call
Intraday BUY SELL Signals
SPRO
Price
$2.29
Change
+$0.15 (+7.01%)
Updated
Feb 4 closing price
Capitalization
128.45M
49 days until earnings call
Intraday BUY SELL Signals
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CLGN vs SPRO

Header iconCLGN vs SPRO Comparison
Open Charts CLGN vs SPROBanner chart's image
CollPlant Biotechnologies
Price$1.62
Change-$0.06 (-3.57%)
Volume$400
Capitalization21.08M
Spero Therapeutics
Price$2.29
Change+$0.15 (+7.01%)
Volume$937.76K
Capitalization128.45M
CLGN vs SPRO Comparison Chart in %
CLGN
Daily Signal:
Gain/Loss:
SPRO
Daily Signal:
Gain/Loss:
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CLGN vs. SPRO commentary
Feb 05, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is CLGN is a Buy and SPRO is a Hold.

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COMPARISON
Comparison
Feb 05, 2026
Stock price -- (CLGN: $1.68 vs. SPRO: $2.14)
Brand notoriety: CLGN and SPRO are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: CLGN: 53% vs. SPRO: 169%
Market capitalization -- CLGN: $21.08M vs. SPRO: $128.45M
CLGN [@Biotechnology] is valued at $21.08M. SPRO’s [@Biotechnology] market capitalization is $128.45M. The market cap for tickers in the [@Biotechnology] industry ranges from $119.38B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

CLGN’s FA Score shows that 1 FA rating(s) are green whileSPRO’s FA Score has 1 green FA rating(s).

  • CLGN’s FA Score: 1 green, 4 red.
  • SPRO’s FA Score: 1 green, 4 red.
According to our system of comparison, SPRO is a better buy in the long-term than CLGN.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

CLGN’s TA Score shows that 5 TA indicator(s) are bullish while SPRO’s TA Score has 4 bullish TA indicator(s).

  • CLGN’s TA Score: 5 bullish, 5 bearish.
  • SPRO’s TA Score: 4 bullish, 6 bearish.
According to our system of comparison, CLGN is a better buy in the short-term than SPRO.

Price Growth

CLGN (@Biotechnology) experienced а -13.67% price change this week, while SPRO (@Biotechnology) price change was -9.70% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -2.56%. For the same industry, the average monthly price growth was +1.40%, and the average quarterly price growth was +33.10%.

Reported Earning Dates

CLGN is expected to report earnings on Apr 02, 2026.

SPRO is expected to report earnings on Mar 26, 2026.

Industries' Descriptions

@Biotechnology (-2.56% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SPRO($128M) has a higher market cap than CLGN($21.1M). CLGN YTD gains are higher at: 20.000 vs. SPRO (-8.154). CLGN has higher annual earnings (EBITDA): -11.37M vs. SPRO (-45.09M). SPRO has more cash in the bank: 48.6M vs. CLGN (8.55M). CLGN has less debt than SPRO: CLGN (2.94M) vs SPRO (3.35M). SPRO has higher revenues than CLGN: SPRO (29.3M) vs CLGN (2.48M).
CLGNSPROCLGN / SPRO
Capitalization21.1M128M16%
EBITDA-11.37M-45.09M25%
Gain YTD20.000-8.154-245%
P/E RatioN/A10.75-
Revenue2.48M29.3M8%
Total Cash8.55M48.6M18%
Total Debt2.94M3.35M88%
FUNDAMENTALS RATINGS
CLGN vs SPRO: Fundamental Ratings
CLGN
SPRO
OUTLOOK RATING
1..100
7966
VALUATION
overvalued / fair valued / undervalued
1..100
98
Overvalued
61
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9999
PRICE GROWTH RATING
1..100
6244
P/E GROWTH RATING
1..100
15
SEASONALITY SCORE
1..100
9050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SPRO's Valuation (61) in the Pharmaceuticals Major industry is somewhat better than the same rating for CLGN (98) in the Biotechnology industry. This means that SPRO’s stock grew somewhat faster than CLGN’s over the last 12 months.

SPRO's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as CLGN (100) in the Biotechnology industry. This means that SPRO’s stock grew similarly to CLGN’s over the last 12 months.

SPRO's SMR Rating (99) in the Pharmaceuticals Major industry is in the same range as CLGN (99) in the Biotechnology industry. This means that SPRO’s stock grew similarly to CLGN’s over the last 12 months.

SPRO's Price Growth Rating (44) in the Pharmaceuticals Major industry is in the same range as CLGN (62) in the Biotechnology industry. This means that SPRO’s stock grew similarly to CLGN’s over the last 12 months.

CLGN's P/E Growth Rating (1) in the Biotechnology industry is in the same range as SPRO (5) in the Pharmaceuticals Major industry. This means that CLGN’s stock grew similarly to SPRO’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
CLGNSPRO
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
90%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
77%
Momentum
ODDS (%)
Bullish Trend 2 days ago
77%
Bearish Trend 2 days ago
86%
MACD
ODDS (%)
Bullish Trend 2 days ago
81%
Bearish Trend 2 days ago
89%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
90%
Bearish Trend 2 days ago
87%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
76%
Bearish Trend 2 days ago
88%
Advances
ODDS (%)
Bullish Trend 13 days ago
80%
Bullish Trend 29 days ago
69%
Declines
ODDS (%)
Bearish Trend 2 days ago
88%
Bearish Trend 8 days ago
89%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
73%
Aroon
ODDS (%)
Bullish Trend 2 days ago
82%
Bullish Trend 2 days ago
75%
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CLGN
Daily Signal:
Gain/Loss:
SPRO
Daily Signal:
Gain/Loss:
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CLGN and

Correlation & Price change

A.I.dvisor indicates that over the last year, CLGN has been loosely correlated with SPRO. These tickers have moved in lockstep 41% of the time. This A.I.-generated data suggests there is some statistical probability that if CLGN jumps, then SPRO could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To CLGN
1D Price
Change %
CLGN100%
-8.70%
SPRO - CLGN
41%
Loosely correlated
-4.04%
CMVLF - CLGN
37%
Loosely correlated
N/A
CLLS - CLGN
33%
Poorly correlated
-7.59%
ALZN - CLGN
28%
Poorly correlated
-3.69%
NEVPF - CLGN
26%
Poorly correlated
N/A
More

SPRO and

Correlation & Price change

A.I.dvisor indicates that over the last year, SPRO has been loosely correlated with ASBP. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SPRO jumps, then ASBP could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SPRO
1D Price
Change %
SPRO100%
-4.04%
ASBP - SPRO
58%
Loosely correlated
-4.12%
CLGN - SPRO
37%
Loosely correlated
-8.70%
XENE - SPRO
32%
Poorly correlated
+1.62%
MGTX - SPRO
30%
Poorly correlated
+2.68%
MTVA - SPRO
30%
Poorly correlated
-17.75%
More