BCYC
Price
$6.00
Change
-$2.87 (-32.36%)
Updated
Feb 3 closing price
Capitalization
415.17M
27 days until earnings call
Intraday BUY SELL Signals
SYRE
Price
$33.29
Change
+$12.12 (+57.25%)
Updated
Feb 3 closing price
Capitalization
2.54B
22 days until earnings call
Intraday BUY SELL Signals
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BCYC vs SYRE

Header iconBCYC vs SYRE Comparison
Open Charts BCYC vs SYREBanner chart's image
Bicycle Therapeutics
Price$6.00
Change-$2.87 (-32.36%)
Volume$696.15K
Capitalization415.17M
Spyre Therapeutics
Price$33.29
Change+$12.12 (+57.25%)
Volume$453.78K
Capitalization2.54B
BCYC vs SYRE Comparison Chart in %
BCYC
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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VS
BCYC vs. SYRE commentary
Feb 04, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is BCYC is a Hold and SYRE is a Hold.

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COMPARISON
Comparison
Feb 04, 2026
Stock price -- (BCYC: $6.00 vs. SYRE: $33.29)
Brand notoriety: BCYC and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: BCYC: 269% vs. SYRE: 62%
Market capitalization -- BCYC: $415.17M vs. SYRE: $2.59B
BCYC [@Biotechnology] is valued at $415.17M. SYRE’s [@Biotechnology] market capitalization is $2.59B. The market cap for tickers in the [@Biotechnology] industry ranges from $118.13B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

BCYC’s FA Score shows that 1 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • BCYC’s FA Score: 1 green, 4 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, both BCYC and SYRE are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

BCYC’s TA Score shows that 3 TA indicator(s) are bullish while SYRE’s TA Score has 2 bullish TA indicator(s).

  • BCYC’s TA Score: 3 bullish, 5 bearish.
  • SYRE’s TA Score: 2 bullish, 4 bearish.
According to our system of comparison, both BCYC and SYRE are a bad buy in the short-term.

Price Growth

BCYC (@Biotechnology) experienced а -15.13% price change this week, while SYRE (@Biotechnology) price change was -0.21% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was -4.22%. For the same industry, the average monthly price growth was +3.03%, and the average quarterly price growth was +35.17%.

Reported Earning Dates

BCYC is expected to report earnings on Mar 03, 2026.

SYRE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (-4.22% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($2.54B) has a higher market cap than BCYC($415M). SYRE YTD gains are higher at: -0.031 vs. BCYC (-15.254). SYRE has higher annual earnings (EBITDA): -223.64M vs. BCYC (-245.86M). BCYC has more cash in the bank: 648M vs. SYRE (486M). SYRE has less debt than BCYC: SYRE (0) vs BCYC (5.74M). BCYC has higher revenues than SYRE: BCYC (28.3M) vs SYRE (0).
BCYCSYREBCYC / SYRE
Capitalization415M2.54B16%
EBITDA-245.86M-223.64M110%
Gain YTD-15.254-0.03149,981%
P/E RatioN/A1.72-
Revenue28.3M0-
Total Cash648M486M133%
Total Debt5.74M0-
FUNDAMENTALS RATINGS
BCYC vs SYRE: Fundamental Ratings
BCYC
SYRE
OUTLOOK RATING
1..100
311
VALUATION
overvalued / fair valued / undervalued
1..100
15
Undervalued
70
Overvalued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
9697
PRICE GROWTH RATING
1..100
7939
P/E GROWTH RATING
1..100
10078
SEASONALITY SCORE
1..100
8550

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

BCYC's Valuation (15) in the null industry is somewhat better than the same rating for SYRE (70) in the Pharmaceuticals Major industry. This means that BCYC’s stock grew somewhat faster than SYRE’s over the last 12 months.

BCYC's Profit vs Risk Rating (100) in the null industry is in the same range as SYRE (100) in the Pharmaceuticals Major industry. This means that BCYC’s stock grew similarly to SYRE’s over the last 12 months.

BCYC's SMR Rating (96) in the null industry is in the same range as SYRE (97) in the Pharmaceuticals Major industry. This means that BCYC’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's Price Growth Rating (39) in the Pharmaceuticals Major industry is somewhat better than the same rating for BCYC (79) in the null industry. This means that SYRE’s stock grew somewhat faster than BCYC’s over the last 12 months.

SYRE's P/E Growth Rating (78) in the Pharmaceuticals Major industry is in the same range as BCYC (100) in the null industry. This means that SYRE’s stock grew similarly to BCYC’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
BCYCSYRE
RSI
ODDS (%)
N/A
N/A
Stochastic
ODDS (%)
Bullish Trend 1 day ago
83%
Bearish Trend 3 days ago
90%
Momentum
ODDS (%)
Bearish Trend 1 day ago
88%
Bearish Trend 3 days ago
88%
MACD
ODDS (%)
Bearish Trend 1 day ago
90%
Bearish Trend 3 days ago
89%
TrendWeek
ODDS (%)
Bearish Trend 1 day ago
88%
Bullish Trend 3 days ago
84%
TrendMonth
ODDS (%)
Bearish Trend 1 day ago
86%
Bullish Trend 3 days ago
83%
Advances
ODDS (%)
Bullish Trend 9 days ago
81%
Bullish Trend 9 days ago
86%
Declines
ODDS (%)
Bearish Trend 6 days ago
88%
Bearish Trend about 1 month ago
89%
BollingerBands
ODDS (%)
Bullish Trend 1 day ago
90%
Bullish Trend 3 days ago
79%
Aroon
ODDS (%)
Bearish Trend 1 day ago
81%
Bearish Trend 3 days ago
89%
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BCYC
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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BCYC and

Correlation & Price change

A.I.dvisor indicates that over the last year, BCYC has been loosely correlated with NRIX. These tickers have moved in lockstep 53% of the time. This A.I.-generated data suggests there is some statistical probability that if BCYC jumps, then NRIX could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To BCYC
1D Price
Change %
BCYC100%
-7.55%
NRIX - BCYC
53%
Loosely correlated
-1.76%
NGNE - BCYC
51%
Loosely correlated
-4.20%
SYRE - BCYC
51%
Loosely correlated
+1.65%
RLAY - BCYC
48%
Loosely correlated
+6.38%
SLDB - BCYC
47%
Loosely correlated
+1.71%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with BEAM. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then BEAM could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
+2.41%
BEAM - SYRE
58%
Loosely correlated
+1.09%
ORKA - SYRE
57%
Loosely correlated
+0.20%
XNCR - SYRE
56%
Loosely correlated
+0.17%
RGNX - SYRE
55%
Loosely correlated
-3.41%
APGE - SYRE
54%
Loosely correlated
+0.18%
More