ATXS
Price
$13.13
Change
+$0.04 (+0.31%)
Updated
Dec 4, 11:40 AM (EDT)
Capitalization
747.24M
91 days until earnings call
Intraday BUY SELL Signals
SYRE
Price
$32.20
Change
+$3.80 (+13.38%)
Updated
Dec 3 closing price
Capitalization
2.5B
84 days until earnings call
Intraday BUY SELL Signals
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ATXS vs SYRE

Header iconATXS vs SYRE Comparison
Open Charts ATXS vs SYREBanner chart's image
Astria Therapeutics
Price$13.13
Change+$0.04 (+0.31%)
Volume$1.61K
Capitalization747.24M
Spyre Therapeutics
Price$32.20
Change+$3.80 (+13.38%)
Volume$1.31M
Capitalization2.5B
ATXS vs SYRE Comparison Chart in %
ATXS
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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VS
ATXS vs. SYRE commentary
Dec 04, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is ATXS is a StrongBuy and SYRE is a Hold.

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COMPARISON
Comparison
Dec 04, 2025
Stock price -- (ATXS: $12.60 vs. SYRE: $28.40)
Brand notoriety: ATXS and SYRE are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: ATXS: 11% vs. SYRE: 23%
Market capitalization -- ATXS: $747.24M vs. SYRE: $2.5B
ATXS [@Biotechnology] is valued at $747.24M. SYRE’s [@Biotechnology] market capitalization is $2.5B. The market cap for tickers in the [@Biotechnology] industry ranges from $117.5B to $0. The average market capitalization across the [@Biotechnology] industry is $2.19B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

ATXS’s FA Score shows that 0 FA rating(s) are green whileSYRE’s FA Score has 0 green FA rating(s).

  • ATXS’s FA Score: 0 green, 5 red.
  • SYRE’s FA Score: 0 green, 5 red.
According to our system of comparison, both ATXS and SYRE are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

ATXS’s TA Score shows that 4 TA indicator(s) are bullish while SYRE’s TA Score has 4 bullish TA indicator(s).

  • ATXS’s TA Score: 4 bullish, 4 bearish.
  • SYRE’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, both ATXS and SYRE are a good buy in the short-term.

Price Growth

ATXS (@Biotechnology) experienced а +2.11% price change this week, while SYRE (@Biotechnology) price change was -2.74% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.32%. For the same industry, the average monthly price growth was +1.23%, and the average quarterly price growth was +54.93%.

Reported Earning Dates

ATXS is expected to report earnings on Mar 05, 2026.

SYRE is expected to report earnings on Feb 26, 2026.

Industries' Descriptions

@Biotechnology (+0.32% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
SYRE($2.5B) has a higher market cap than ATXS($747M). ATXS YTD gains are higher at: 40.940 vs. SYRE (21.993). ATXS has higher annual earnings (EBITDA): -131.42M vs. SYRE (-222.15M). SYRE has more cash in the bank: 527M vs. ATXS (259M). SYRE has less debt than ATXS: SYRE (0) vs ATXS (4.77M). ATXS (0) and SYRE (0) have equivalent revenues.
ATXSSYREATXS / SYRE
Capitalization747M2.5B30%
EBITDA-131.42M-222.15M59%
Gain YTD40.94021.993186%
P/E RatioN/A1.72-
Revenue00-
Total Cash259M527M49%
Total Debt4.77M0-
FUNDAMENTALS RATINGS
ATXS vs SYRE: Fundamental Ratings
ATXS
SYRE
OUTLOOK RATING
1..100
5050
VALUATION
overvalued / fair valued / undervalued
1..100
76
Overvalued
69
Overvalued
PROFIT vs RISK RATING
1..100
83100
SMR RATING
1..100
9797
PRICE GROWTH RATING
1..100
3636
P/E GROWTH RATING
1..100
10074
SEASONALITY SCORE
1..100
50n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

SYRE's Valuation (69) in the Pharmaceuticals Major industry is in the same range as ATXS (76) in the Biotechnology industry. This means that SYRE’s stock grew similarly to ATXS’s over the last 12 months.

ATXS's Profit vs Risk Rating (83) in the Biotechnology industry is in the same range as SYRE (100) in the Pharmaceuticals Major industry. This means that ATXS’s stock grew similarly to SYRE’s over the last 12 months.

ATXS's SMR Rating (97) in the Biotechnology industry is in the same range as SYRE (97) in the Pharmaceuticals Major industry. This means that ATXS’s stock grew similarly to SYRE’s over the last 12 months.

ATXS's Price Growth Rating (36) in the Biotechnology industry is in the same range as SYRE (36) in the Pharmaceuticals Major industry. This means that ATXS’s stock grew similarly to SYRE’s over the last 12 months.

SYRE's P/E Growth Rating (74) in the Pharmaceuticals Major industry is in the same range as ATXS (100) in the Biotechnology industry. This means that SYRE’s stock grew similarly to ATXS’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
ATXSSYRE
RSI
ODDS (%)
Bearish Trend 7 days ago
71%
Bearish Trend 7 days ago
90%
Stochastic
ODDS (%)
Bearish Trend 7 days ago
83%
Bearish Trend 7 days ago
88%
Momentum
ODDS (%)
Bullish Trend 7 days ago
79%
Bullish Trend 7 days ago
87%
MACD
ODDS (%)
Bearish Trend 7 days ago
90%
Bullish Trend 7 days ago
80%
TrendWeek
ODDS (%)
Bullish Trend 7 days ago
82%
Bullish Trend 7 days ago
83%
TrendMonth
ODDS (%)
Bullish Trend 7 days ago
86%
Bullish Trend 7 days ago
83%
Advances
ODDS (%)
Bullish Trend 7 days ago
80%
Bullish Trend 7 days ago
85%
Declines
ODDS (%)
Bearish Trend 10 days ago
90%
Bearish Trend 29 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 7 days ago
86%
Bearish Trend 7 days ago
90%
Aroon
ODDS (%)
Bullish Trend 7 days ago
88%
Bullish Trend 7 days ago
82%
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ATXS
Daily Signal:
Gain/Loss:
SYRE
Daily Signal:
Gain/Loss:
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ATXS and

Correlation & Price change

A.I.dvisor indicates that over the last year, ATXS has been loosely correlated with XENE. These tickers have moved in lockstep 48% of the time. This A.I.-generated data suggests there is some statistical probability that if ATXS jumps, then XENE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ATXS
1D Price
Change %
ATXS100%
-0.16%
XENE - ATXS
48%
Loosely correlated
-1.45%
RGNX - ATXS
48%
Loosely correlated
-3.10%
SYRE - ATXS
48%
Loosely correlated
-0.91%
ORKA - ATXS
45%
Loosely correlated
+0.56%
DYN - ATXS
44%
Loosely correlated
-2.96%
More

SYRE and

Correlation & Price change

A.I.dvisor indicates that over the last year, SYRE has been loosely correlated with APGE. These tickers have moved in lockstep 58% of the time. This A.I.-generated data suggests there is some statistical probability that if SYRE jumps, then APGE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SYRE
1D Price
Change %
SYRE100%
-0.91%
APGE - SYRE
58%
Loosely correlated
+0.20%
CGON - SYRE
58%
Loosely correlated
-4.35%
RGNX - SYRE
57%
Loosely correlated
-3.10%
IDYA - SYRE
57%
Loosely correlated
-1.75%
ORKA - SYRE
56%
Loosely correlated
+0.56%
More