ARWR
Price
$65.91
Change
+$0.37 (+0.56%)
Updated
Jan 14 closing price
Capitalization
9.13B
26 days until earnings call
Intraday BUY SELL Signals
IONS
Price
$78.88
Change
-$0.60 (-0.75%)
Updated
Jan 14, 04:59 PM (EDT)
Capitalization
12.87B
41 days until earnings call
Intraday BUY SELL Signals
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ARWR vs IONS

Header iconARWR vs IONS Comparison
Open Charts ARWR vs IONSBanner chart's image
Arrowhead Pharmaceuticals
Price$65.91
Change+$0.37 (+0.56%)
Volume$1.85M
Capitalization9.13B
Ionis Pharmaceuticals
Price$78.88
Change-$0.60 (-0.75%)
Volume$55.37K
Capitalization12.87B
ARWR vs IONS Comparison Chart in %
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VS
ARWR vs. IONS commentary
Jan 15, 2026

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is ARWR is a Hold and IONS is a Hold.

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COMPARISON
Comparison
Jan 15, 2026
Stock price -- (ARWR: $65.91 vs. IONS: $78.87)
Brand notoriety: ARWR: Notable vs. IONS: Not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: ARWR: 62% vs. IONS: 87%
Market capitalization -- ARWR: $9.13B vs. IONS: $12.77B
ARWR [@Biotechnology] is valued at $9.13B. IONS’s [@Biotechnology] market capitalization is $12.77B. The market cap for tickers in the [@Biotechnology] industry ranges from $114.05B to $0. The average market capitalization across the [@Biotechnology] industry is $2.24B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

ARWR’s FA Score shows that 1 FA rating(s) are green whileIONS’s FA Score has 0 green FA rating(s).

  • ARWR’s FA Score: 1 green, 4 red.
  • IONS’s FA Score: 0 green, 5 red.
According to our system of comparison, ARWR is a better buy in the long-term than IONS.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

ARWR’s TA Score shows that 3 TA indicator(s) are bullish while IONS’s TA Score has 2 bullish TA indicator(s).

  • ARWR’s TA Score: 3 bullish, 4 bearish.
  • IONS’s TA Score: 2 bullish, 5 bearish.
According to our system of comparison, ARWR is a better buy in the short-term than IONS.

Price Growth

ARWR (@Biotechnology) experienced а +0.33% price change this week, while IONS (@Biotechnology) price change was -5.17% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +0.47%. For the same industry, the average monthly price growth was +3.44%, and the average quarterly price growth was +44.89%.

Reported Earning Dates

ARWR is expected to report earnings on Feb 10, 2026.

IONS is expected to report earnings on Feb 25, 2026.

Industries' Descriptions

@Biotechnology (+0.47% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
IONS($12.9B) has a higher market cap than ARWR($9.13B). IONS YTD gains are higher at: 0.468 vs. ARWR (-0.723). ARWR has higher annual earnings (EBITDA): 165M vs. IONS (-153.61M). IONS has more cash in the bank: 2.24B vs. ARWR (919M). ARWR has less debt than IONS: ARWR (366M) vs IONS (1.49B). IONS has higher revenues than ARWR: IONS (967M) vs ARWR (829M).
ARWRIONSARWR / IONS
Capitalization9.13B12.9B71%
EBITDA165M-153.61M-107%
Gain YTD-0.7230.468-155%
P/E RatioN/AN/A-
Revenue829M967M86%
Total Cash919M2.24B41%
Total Debt366M1.49B25%
FUNDAMENTALS RATINGS
ARWR vs IONS: Fundamental Ratings
ARWR
IONS
OUTLOOK RATING
1..100
6212
VALUATION
overvalued / fair valued / undervalued
1..100
100
Overvalued
99
Overvalued
PROFIT vs RISK RATING
1..100
10056
SMR RATING
1..100
9297
PRICE GROWTH RATING
1..100
3537
P/E GROWTH RATING
1..100
268
SEASONALITY SCORE
1..100
50n/a

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

IONS's Valuation (99) in the Biotechnology industry is in the same range as ARWR (100). This means that IONS’s stock grew similarly to ARWR’s over the last 12 months.

IONS's Profit vs Risk Rating (56) in the Biotechnology industry is somewhat better than the same rating for ARWR (100). This means that IONS’s stock grew somewhat faster than ARWR’s over the last 12 months.

ARWR's SMR Rating (92) in the Biotechnology industry is in the same range as IONS (97). This means that ARWR’s stock grew similarly to IONS’s over the last 12 months.

ARWR's Price Growth Rating (35) in the Biotechnology industry is in the same range as IONS (37). This means that ARWR’s stock grew similarly to IONS’s over the last 12 months.

ARWR's P/E Growth Rating (2) in the Biotechnology industry is significantly better than the same rating for IONS (68). This means that ARWR’s stock grew significantly faster than IONS’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
ARWRIONS
RSI
ODDS (%)
Bearish Trend 2 days ago
76%
N/A
Stochastic
ODDS (%)
Bullish Trend 2 days ago
70%
Bearish Trend 2 days ago
71%
Momentum
ODDS (%)
Bearish Trend 2 days ago
86%
Bearish Trend 2 days ago
68%
MACD
ODDS (%)
Bearish Trend 2 days ago
86%
Bearish Trend 2 days ago
62%
TrendWeek
ODDS (%)
Bearish Trend 2 days ago
83%
Bearish Trend 2 days ago
67%
TrendMonth
ODDS (%)
Bearish Trend 2 days ago
83%
Bullish Trend 2 days ago
74%
Advances
ODDS (%)
Bullish Trend 20 days ago
80%
Bullish Trend 8 days ago
66%
Declines
ODDS (%)
Bearish Trend 6 days ago
83%
Bearish Trend 6 days ago
67%
BollingerBands
ODDS (%)
N/A
Bearish Trend 2 days ago
71%
Aroon
ODDS (%)
Bullish Trend 2 days ago
77%
Bullish Trend 2 days ago
77%
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ARWR
Daily Signal:
Gain/Loss:
IONS
Daily Signal:
Gain/Loss:
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ARWR and

Correlation & Price change

A.I.dvisor indicates that over the last year, ARWR has been loosely correlated with DNLI. These tickers have moved in lockstep 48% of the time. This A.I.-generated data suggests there is some statistical probability that if ARWR jumps, then DNLI could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ARWR
1D Price
Change %
ARWR100%
+0.56%
DNLI - ARWR
48%
Loosely correlated
+0.88%
IONS - ARWR
47%
Loosely correlated
-0.77%
ALGS - ARWR
47%
Loosely correlated
-2.06%
AXON - ARWR
46%
Loosely correlated
-1.92%
SYRE - ARWR
46%
Loosely correlated
+5.17%
More

IONS and

Correlation & Price change

A.I.dvisor indicates that over the last year, IONS has been loosely correlated with CYTK. These tickers have moved in lockstep 65% of the time. This A.I.-generated data suggests there is some statistical probability that if IONS jumps, then CYTK could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To IONS
1D Price
Change %
IONS100%
-2.67%
CYTK - IONS
65%
Loosely correlated
-2.03%
MNKD - IONS
50%
Loosely correlated
-2.25%
MLYS - IONS
48%
Loosely correlated
-0.12%
ARWR - IONS
47%
Loosely correlated
-0.58%
IDYA - IONS
47%
Loosely correlated
-4.75%
More