ARWR
Price
$32.80
Change
+$1.14 (+3.60%)
Updated
Sep 26 closing price
Capitalization
4.53B
64 days until earnings call
IONS
Price
$64.09
Change
+$1.12 (+1.78%)
Updated
Sep 26 closing price
Capitalization
10.22B
32 days until earnings call
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ARWR vs IONS

Header iconARWR vs IONS Comparison
Open Charts ARWR vs IONSBanner chart's image
Arrowhead Pharmaceuticals
Price$32.80
Change+$1.14 (+3.60%)
Volume$1.86M
Capitalization4.53B
Ionis Pharmaceuticals
Price$64.09
Change+$1.12 (+1.78%)
Volume$1.52M
Capitalization10.22B
ARWR vs IONS Comparison Chart in %
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ARWR
Daily Signalchanged days ago
Gain/Loss if bought
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IONS
Daily Signalchanged days ago
Gain/Loss if bought
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ARWR vs. IONS commentary
Sep 29, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is ARWR is a StrongBuy and IONS is a StrongBuy.

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COMPARISON
Comparison
Sep 29, 2025
Stock price -- (ARWR: $32.80 vs. IONS: $64.09)
Brand notoriety: ARWR: Notable vs. IONS: Not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: ARWR: 74% vs. IONS: 58%
Market capitalization -- ARWR: $4.53B vs. IONS: $10.22B
ARWR [@Biotechnology] is valued at $4.53B. IONS’s [@Biotechnology] market capitalization is $10.22B. The market cap for tickers in the [@Biotechnology] industry ranges from $98.9B to $0. The average market capitalization across the [@Biotechnology] industry is $1.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

ARWR’s FA Score shows that 1 FA rating(s) are green whileIONS’s FA Score has 0 green FA rating(s).

  • ARWR’s FA Score: 1 green, 4 red.
  • IONS’s FA Score: 0 green, 5 red.
According to our system of comparison, ARWR is a better buy in the long-term than IONS.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

ARWR’s TA Score shows that 3 TA indicator(s) are bullish while IONS’s TA Score has 3 bullish TA indicator(s).

  • ARWR’s TA Score: 3 bullish, 3 bearish.
  • IONS’s TA Score: 3 bullish, 5 bearish.
According to our system of comparison, ARWR is a better buy in the short-term than IONS.

Price Growth

ARWR (@Biotechnology) experienced а +6.88% price change this week, while IONS (@Biotechnology) price change was +5.05% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.00%. For the same industry, the average monthly price growth was +9.18%, and the average quarterly price growth was +54.60%.

Reported Earning Dates

ARWR is expected to report earnings on Dec 01, 2025.

IONS is expected to report earnings on Oct 30, 2025.

Industries' Descriptions

@Biotechnology (+4.00% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
IONS($10.2B) has a higher market cap than ARWR($4.54B). IONS YTD gains are higher at: 83.324 vs. ARWR (74.468). ARWR has higher annual earnings (EBITDA): -52.51M vs. IONS (-170.69M). IONS has more cash in the bank: 2.29B vs. ARWR (900M). ARWR has less debt than IONS: ARWR (353M) vs IONS (1.42B). IONS has higher revenues than ARWR: IONS (944M) vs ARWR (573M).
ARWRIONSARWR / IONS
Capitalization4.54B10.2B44%
EBITDA-52.51M-170.69M31%
Gain YTD74.46883.32489%
P/E RatioN/AN/A-
Revenue573M944M61%
Total Cash900M2.29B39%
Total Debt353M1.42B25%
FUNDAMENTALS RATINGS
ARWR vs IONS: Fundamental Ratings
ARWR
IONS
OUTLOOK RATING
1..100
4137
VALUATION
overvalued / fair valued / undervalued
1..100
94
Overvalued
95
Overvalued
PROFIT vs RISK RATING
1..100
10077
SMR RATING
1..100
9798
PRICE GROWTH RATING
1..100
3536
P/E GROWTH RATING
1..100
260
SEASONALITY SCORE
1..100
5050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

ARWR's Valuation (94) in the Biotechnology industry is in the same range as IONS (95). This means that ARWR’s stock grew similarly to IONS’s over the last 12 months.

IONS's Profit vs Risk Rating (77) in the Biotechnology industry is in the same range as ARWR (100). This means that IONS’s stock grew similarly to ARWR’s over the last 12 months.

ARWR's SMR Rating (97) in the Biotechnology industry is in the same range as IONS (98). This means that ARWR’s stock grew similarly to IONS’s over the last 12 months.

ARWR's Price Growth Rating (35) in the Biotechnology industry is in the same range as IONS (36). This means that ARWR’s stock grew similarly to IONS’s over the last 12 months.

ARWR's P/E Growth Rating (2) in the Biotechnology industry is somewhat better than the same rating for IONS (60). This means that ARWR’s stock grew somewhat faster than IONS’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
ARWRIONS
RSI
ODDS (%)
Bearish Trend 3 days ago
81%
Bearish Trend 3 days ago
76%
Stochastic
ODDS (%)
Bearish Trend 3 days ago
84%
Bearish Trend 3 days ago
82%
Momentum
ODDS (%)
N/A
Bullish Trend 3 days ago
69%
MACD
ODDS (%)
N/A
Bearish Trend 3 days ago
69%
TrendWeek
ODDS (%)
Bullish Trend 3 days ago
77%
Bullish Trend 3 days ago
70%
TrendMonth
ODDS (%)
Bullish Trend 3 days ago
75%
Bullish Trend 3 days ago
72%
Advances
ODDS (%)
Bullish Trend 5 days ago
80%
Bullish Trend 5 days ago
65%
Declines
ODDS (%)
N/A
Bearish Trend 14 days ago
67%
BollingerBands
ODDS (%)
Bearish Trend 3 days ago
85%
Bearish Trend 3 days ago
67%
Aroon
ODDS (%)
Bullish Trend 3 days ago
73%
Bullish Trend 3 days ago
68%
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ARWR
Daily Signalchanged days ago
Gain/Loss if bought
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IONS
Daily Signalchanged days ago
Gain/Loss if bought
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ARWR and

Correlation & Price change

A.I.dvisor indicates that over the last year, ARWR has been loosely correlated with DNLI. These tickers have moved in lockstep 52% of the time. This A.I.-generated data suggests there is some statistical probability that if ARWR jumps, then DNLI could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To ARWR
1D Price
Change %
ARWR100%
+3.60%
DNLI - ARWR
52%
Loosely correlated
+3.87%
IMNM - ARWR
50%
Loosely correlated
+14.13%
IPSC - ARWR
49%
Loosely correlated
+4.39%
RGNX - ARWR
48%
Loosely correlated
+3.10%
IONS - ARWR
47%
Loosely correlated
+1.78%
More

IONS and

Correlation & Price change

A.I.dvisor indicates that over the last year, IONS has been loosely correlated with CYTK. These tickers have moved in lockstep 63% of the time. This A.I.-generated data suggests there is some statistical probability that if IONS jumps, then CYTK could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To IONS
1D Price
Change %
IONS100%
+1.78%
CYTK - IONS
63%
Loosely correlated
+5.37%
MLYS - IONS
52%
Loosely correlated
+3.84%
IDYA - IONS
48%
Loosely correlated
+4.44%
MNKD - IONS
48%
Loosely correlated
+3.75%
CRNX - IONS
48%
Loosely correlated
+27.92%
More