APGE
Price
$62.97
Change
-$0.13 (-0.21%)
Updated
Nov 13, 04:59 PM (EDT)
Capitalization
4.3B
Intraday BUY SELL Signals
SEPN
Price
$19.24
Change
+$0.01 (+0.05%)
Updated
Nov 13 closing price
Capitalization
862.13M
Intraday BUY SELL Signals
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APGE vs SEPN

Header iconAPGE vs SEPN Comparison
Open Charts APGE vs SEPNBanner chart's image
Apogee Therapeutics
Price$62.97
Change-$0.13 (-0.21%)
Volume$94.09K
Capitalization4.3B
Septerna
Price$19.24
Change+$0.01 (+0.05%)
Volume$150.95K
Capitalization862.13M
APGE vs SEPN Comparison Chart in %
APGE
Daily Signal:
Gain/Loss:
SEPN
Daily Signal:
Gain/Loss:
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VS
APGE vs. SEPN commentary
Nov 14, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is APGE is a StrongBuy and SEPN is a Hold.

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COMPARISON
Comparison
Nov 14, 2025
Stock price -- (APGE: $63.10 vs. SEPN: $19.23)
Brand notoriety: APGE and SEPN are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: APGE: 93% vs. SEPN: 73%
Market capitalization -- APGE: $4.3B vs. SEPN: $862.13M
APGE [@Biotechnology] is valued at $4.3B. SEPN’s [@Biotechnology] market capitalization is $862.13M. The market cap for tickers in the [@Biotechnology] industry ranges from $110.25B to $0. The average market capitalization across the [@Biotechnology] industry is $2.1B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

APGE’s FA Score shows that 0 FA rating(s) are green whileSEPN’s FA Score has 1 green FA rating(s).

  • APGE’s FA Score: 0 green, 5 red.
  • SEPN’s FA Score: 1 green, 4 red.
According to our system of comparison, both APGE and SEPN are a bad buy in the long-term.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

APGE’s TA Score shows that 4 TA indicator(s) are bullish while SEPN’s TA Score has 4 bullish TA indicator(s).

  • APGE’s TA Score: 4 bullish, 4 bearish.
  • SEPN’s TA Score: 4 bullish, 4 bearish.
According to our system of comparison, both APGE and SEPN are a good buy in the short-term.

Price Growth

APGE (@Biotechnology) experienced а +13.80% price change this week, while SEPN (@Biotechnology) price change was +0.52% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +1.51%. For the same industry, the average monthly price growth was -3.12%, and the average quarterly price growth was +61.90%.

Industries' Descriptions

@Biotechnology (+1.51% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
APGE($4.3B) has a higher market cap than SEPN($862M). APGE YTD gains are higher at: 39.294 vs. SEPN (-16.026). SEPN has higher annual earnings (EBITDA): -100.6M vs. APGE (-270.1M). APGE has more cash in the bank: 505M vs. SEPN (327M). APGE has less debt than SEPN: APGE (10.8M) vs SEPN (24.6M). SEPN has higher revenues than APGE: SEPN (726K) vs APGE (0).
APGESEPNAPGE / SEPN
Capitalization4.3B862M499%
EBITDA-270.1M-100.6M268%
Gain YTD39.294-16.026-245%
P/E RatioN/AN/A-
Revenue0726K-
Total Cash505M327M154%
Total Debt10.8M24.6M44%
TECHNICAL ANALYSIS
Technical Analysis
APGESEPN
RSI
ODDS (%)
Bearish Trend 2 days ago
90%
Bullish Trend 2 days ago
40%
Stochastic
ODDS (%)
Bearish Trend 2 days ago
82%
Bullish Trend 2 days ago
82%
Momentum
ODDS (%)
Bullish Trend 2 days ago
83%
Bearish Trend 2 days ago
73%
MACD
ODDS (%)
Bullish Trend 2 days ago
74%
Bearish Trend 2 days ago
33%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
84%
Bullish Trend 2 days ago
90%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
83%
Bearish Trend 2 days ago
85%
Advances
ODDS (%)
Bullish Trend 2 days ago
84%
N/A
Declines
ODDS (%)
Bearish Trend 7 days ago
70%
Bearish Trend 4 days ago
78%
BollingerBands
ODDS (%)
Bearish Trend 2 days ago
80%
Bullish Trend 2 days ago
75%
Aroon
ODDS (%)
Bullish Trend 2 days ago
90%
Bearish Trend 2 days ago
83%
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APGE
Daily Signal:
Gain/Loss:
SEPN
Daily Signal:
Gain/Loss:
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APGE and

Correlation & Price change

A.I.dvisor indicates that over the last year, APGE has been loosely correlated with SYRE. These tickers have moved in lockstep 59% of the time. This A.I.-generated data suggests there is some statistical probability that if APGE jumps, then SYRE could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To APGE
1D Price
Change %
APGE100%
+0.24%
SYRE - APGE
59%
Loosely correlated
+0.34%
NUVL - APGE
51%
Loosely correlated
+0.91%
IRON - APGE
51%
Loosely correlated
-0.06%
CLDX - APGE
50%
Loosely correlated
-0.49%
ELVN - APGE
50%
Loosely correlated
+3.36%
More

SEPN and

Correlation & Price change

A.I.dvisor indicates that over the last year, SEPN has been loosely correlated with RCUS. These tickers have moved in lockstep 41% of the time. This A.I.-generated data suggests there is some statistical probability that if SEPN jumps, then RCUS could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To SEPN
1D Price
Change %
SEPN100%
-0.05%
RCUS - SEPN
41%
Loosely correlated
-1.43%
APGE - SEPN
35%
Loosely correlated
+0.24%
IMTX - SEPN
35%
Loosely correlated
+16.10%
CGON - SEPN
31%
Poorly correlated
+1.47%
IMNM - SEPN
31%
Poorly correlated
-0.51%
More