AGIO
Price
$29.17
Change
+$4.58 (+18.63%)
Updated
Dec 24 closing price
Capitalization
1.7B
49 days until earnings call
Intraday BUY SELL Signals
TPST
Price
$3.08
Change
+$0.04 (+1.32%)
Updated
Dec 24 closing price
Capitalization
15.18M
Intraday BUY SELL Signals
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AGIO vs TPST

Header iconAGIO vs TPST Comparison
Open Charts AGIO vs TPSTBanner chart's image
Agios Pharmaceuticals
Price$29.17
Change+$4.58 (+18.63%)
Volume$6.31M
Capitalization1.7B
Tempest Therapeutics
Price$3.08
Change+$0.04 (+1.32%)
Volume$61.7K
Capitalization15.18M
AGIO vs TPST Comparison Chart in %
AGIO
Daily Signal:
Gain/Loss:
TPST
Daily Signal:
Gain/Loss:
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AGIO vs. TPST commentary
Dec 26, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is AGIO is a StrongBuy and TPST is a Hold.

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COMPARISON
Comparison
Dec 26, 2025
Stock price -- (AGIO: $29.17 vs. TPST: $3.08)
Brand notoriety: AGIO and TPST are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: AGIO: 360% vs. TPST: 47%
Market capitalization -- AGIO: $1.7B vs. TPST: $15.18M
AGIO [@Biotechnology] is valued at $1.7B. TPST’s [@Biotechnology] market capitalization is $15.18M. The market cap for tickers in the [@Biotechnology] industry ranges from $117.47B to $0. The average market capitalization across the [@Biotechnology] industry is $2.23B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

AGIO’s FA Score shows that 0 FA rating(s) are green whileTPST’s FA Score has 0 green FA rating(s).

  • AGIO’s FA Score: 0 green, 5 red.
  • TPST’s FA Score: 0 green, 5 red.
According to our system of comparison, AGIO is a better buy in the long-term than TPST.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

AGIO’s TA Score shows that 6 TA indicator(s) are bullish while TPST’s TA Score has 5 bullish TA indicator(s).

  • AGIO’s TA Score: 6 bullish, 3 bearish.
  • TPST’s TA Score: 5 bullish, 4 bearish.
According to our system of comparison, AGIO is a better buy in the short-term than TPST.

Price Growth

AGIO (@Biotechnology) experienced а +14.62% price change this week, while TPST (@Biotechnology) price change was +5.12% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +2.88%. For the same industry, the average monthly price growth was +4.46%, and the average quarterly price growth was +55.39%.

Reported Earning Dates

AGIO is expected to report earnings on Feb 12, 2026.

Industries' Descriptions

@Biotechnology (+2.88% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
AGIO($1.7B) has a higher market cap than TPST($15.2M). AGIO YTD gains are higher at: -11.229 vs. TPST (-71.609). TPST has higher annual earnings (EBITDA): -35.35M vs. AGIO (-470.31M). AGIO has more cash in the bank: 953M vs. TPST (7.51M). TPST has less debt than AGIO: TPST (8.41M) vs AGIO (44.5M). AGIO has higher revenues than TPST: AGIO (44.8M) vs TPST (0).
AGIOTPSTAGIO / TPST
Capitalization1.7B15.2M11,191%
EBITDA-470.31M-35.35M1,330%
Gain YTD-11.229-71.60916%
P/E Ratio3.82N/A-
Revenue44.8M0-
Total Cash953M7.51M12,683%
Total Debt44.5M8.41M529%
FUNDAMENTALS RATINGS
AGIO vs TPST: Fundamental Ratings
AGIO
TPST
OUTLOOK RATING
1..100
7214
VALUATION
overvalued / fair valued / undervalued
1..100
42
Fair valued
37
Fair valued
PROFIT vs RISK RATING
1..100
100100
SMR RATING
1..100
96100
PRICE GROWTH RATING
1..100
8493
P/E GROWTH RATING
1..100
5088
SEASONALITY SCORE
1..100
n/a50

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

TPST's Valuation (37) in the Pharmaceuticals Major industry is in the same range as AGIO (42) in the Biotechnology industry. This means that TPST’s stock grew similarly to AGIO’s over the last 12 months.

TPST's Profit vs Risk Rating (100) in the Pharmaceuticals Major industry is in the same range as AGIO (100) in the Biotechnology industry. This means that TPST’s stock grew similarly to AGIO’s over the last 12 months.

AGIO's SMR Rating (96) in the Biotechnology industry is in the same range as TPST (100) in the Pharmaceuticals Major industry. This means that AGIO’s stock grew similarly to TPST’s over the last 12 months.

AGIO's Price Growth Rating (84) in the Biotechnology industry is in the same range as TPST (93) in the Pharmaceuticals Major industry. This means that AGIO’s stock grew similarly to TPST’s over the last 12 months.

AGIO's P/E Growth Rating (50) in the Biotechnology industry is somewhat better than the same rating for TPST (88) in the Pharmaceuticals Major industry. This means that AGIO’s stock grew somewhat faster than TPST’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
AGIOTPST
RSI
ODDS (%)
Bullish Trend 2 days ago
58%
Bullish Trend 2 days ago
81%
Stochastic
ODDS (%)
Bullish Trend 2 days ago
78%
Bullish Trend 2 days ago
86%
Momentum
ODDS (%)
Bullish Trend 2 days ago
82%
Bearish Trend 2 days ago
90%
MACD
ODDS (%)
Bullish Trend 2 days ago
77%
Bullish Trend 2 days ago
90%
TrendWeek
ODDS (%)
Bullish Trend 2 days ago
79%
Bullish Trend 2 days ago
78%
TrendMonth
ODDS (%)
Bullish Trend 2 days ago
81%
Bearish Trend 2 days ago
90%
Advances
ODDS (%)
Bullish Trend 28 days ago
77%
Bullish Trend 7 days ago
81%
Declines
ODDS (%)
Bearish Trend 7 days ago
75%
Bearish Trend 11 days ago
90%
BollingerBands
ODDS (%)
Bullish Trend 2 days ago
71%
Bullish Trend 4 days ago
76%
Aroon
ODDS (%)
N/A
Bearish Trend 2 days ago
88%
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AGIO
Daily Signal:
Gain/Loss:
TPST
Daily Signal:
Gain/Loss:
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AGIO and

Correlation & Price change

A.I.dvisor indicates that over the last year, AGIO has been loosely correlated with TPST. These tickers have moved in lockstep 55% of the time. This A.I.-generated data suggests there is some statistical probability that if AGIO jumps, then TPST could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To AGIO
1D Price
Change %
AGIO100%
+18.63%
TPST - AGIO
55%
Loosely correlated
+1.32%
AXON - AGIO
45%
Loosely correlated
+0.02%
NRIX - AGIO
45%
Loosely correlated
+0.36%
RAPT - AGIO
41%
Loosely correlated
+1.24%
VCYT - AGIO
38%
Loosely correlated
-0.35%
More

TPST and

Correlation & Price change

A.I.dvisor indicates that over the last year, TPST has been loosely correlated with AGIO. These tickers have moved in lockstep 54% of the time. This A.I.-generated data suggests there is some statistical probability that if TPST jumps, then AGIO could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To TPST
1D Price
Change %
TPST100%
+1.32%
AGIO - TPST
54%
Loosely correlated
+18.63%
PHIO - TPST
49%
Loosely correlated
+1.94%
NRIX - TPST
40%
Loosely correlated
+0.36%
PVLA - TPST
35%
Loosely correlated
+5.55%
GLMD - TPST
34%
Loosely correlated
+0.03%
More