AGIO
Price
$38.93
Change
+$2.32 (+6.34%)
Updated
Sep 26 closing price
Capitalization
2.26B
32 days until earnings call
LGND
Price
$169.72
Change
+$2.96 (+1.78%)
Updated
Sep 26 closing price
Capitalization
3.31B
38 days until earnings call
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AGIO vs LGND

Header iconAGIO vs LGND Comparison
Open Charts AGIO vs LGNDBanner chart's image
Agios Pharmaceuticals
Price$38.93
Change+$2.32 (+6.34%)
Volume$814.46K
Capitalization2.26B
Ligand Pharmaceuticals
Price$169.72
Change+$2.96 (+1.78%)
Volume$177.43K
Capitalization3.31B
AGIO vs LGND Comparison Chart in %
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AGIO
Daily Signalchanged days ago
Gain/Loss if bought
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LGND
Daily Signalchanged days ago
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AGIO vs. LGND commentary
Sep 29, 2025

To compare these two companies we present long-term analysis, their fundamental ratings and make comparative short-term technical analysis which are presented below. The conclusion is AGIO is a StrongBuy and LGND is a Buy.

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COMPARISON
Comparison
Sep 29, 2025
Stock price -- (AGIO: $38.93 vs. LGND: $169.72)
Brand notoriety: AGIO and LGND are both not notable
Both companies represent the Biotechnology industry
Current volume relative to the 65-day Moving Average: AGIO: 95% vs. LGND: 71%
Market capitalization -- AGIO: $2.26B vs. LGND: $3.31B
AGIO [@Biotechnology] is valued at $2.26B. LGND’s [@Biotechnology] market capitalization is $3.31B. The market cap for tickers in the [@Biotechnology] industry ranges from $98.9B to $0. The average market capitalization across the [@Biotechnology] industry is $1.89B.

Long-Term Analysis

It is best to consider a long-term outlook for a ticker by using Fundamental Analysis (FA) ratings. The rating of 1 to 100, where 1 is best and 100 is worst, is divided into thirds. The first third (a green rating of 1-33) indicates that the ticker is undervalued; the second third (a grey number between 34 and 66) means that the ticker is valued fairly; and the last third (red number of 67 to 100) reflects that the ticker is undervalued. We use an FA Score to show how many ratings show the ticker to be undervalued (green) or overvalued (red).

AGIO’s FA Score shows that 1 FA rating(s) are green whileLGND’s FA Score has 0 green FA rating(s).

  • AGIO’s FA Score: 1 green, 4 red.
  • LGND’s FA Score: 0 green, 5 red.
According to our system of comparison, AGIO is a better buy in the long-term than LGND.

Short-Term Analysis

It is best to consider a short-term outlook for a ticker by using Technical Analysis (TA) indicators. We use Odds of Success as the percentage of outcomes which confirm successful trade signals in the past.

If the Odds of Success (the likelihood of the continuation of a trend) for each indicator are greater than 50%, then the generated signal is confirmed. A green percentage from 90% to 51% indicates that the ticker is in a bullish trend. A red percentage from 90% - 51% indicates that the ticker is in a bearish trend. All grey percentages are below 50% and are considered not to confirm the trend signal.

AGIO’s TA Score shows that 5 TA indicator(s) are bullish while LGND’s TA Score has 3 bullish TA indicator(s).

  • AGIO’s TA Score: 5 bullish, 4 bearish.
  • LGND’s TA Score: 3 bullish, 5 bearish.
According to our system of comparison, AGIO is a better buy in the short-term than LGND.

Price Growth

AGIO (@Biotechnology) experienced а +3.26% price change this week, while LGND (@Biotechnology) price change was +1.93% for the same time period.

The average weekly price growth across all stocks in the @Biotechnology industry was +4.00%. For the same industry, the average monthly price growth was +9.18%, and the average quarterly price growth was +54.60%.

Reported Earning Dates

AGIO is expected to report earnings on Oct 30, 2025.

LGND is expected to report earnings on Nov 05, 2025.

Industries' Descriptions

@Biotechnology (+4.00% weekly)

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

SUMMARIES
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FUNDAMENTALS
Fundamentals
LGND($3.31B) has a higher market cap than AGIO($2.26B). LGND has higher P/E ratio than AGIO: LGND (46.19) vs AGIO (3.45). LGND YTD gains are higher at: 58.395 vs. AGIO (18.472). LGND has higher annual earnings (EBITDA): -45.94M vs. AGIO (-456.28M). AGIO has more cash in the bank: 939M vs. LGND (255M). LGND has less debt than AGIO: LGND (5.74M) vs AGIO (48.8M). LGND has higher revenues than AGIO: LGND (188M) vs AGIO (40.9M).
AGIOLGNDAGIO / LGND
Capitalization2.26B3.31B68%
EBITDA-456.28M-45.94M993%
Gain YTD18.47258.39532%
P/E Ratio3.4546.197%
Revenue40.9M188M22%
Total Cash939M255M368%
Total Debt48.8M5.74M850%
FUNDAMENTALS RATINGS
AGIO vs LGND: Fundamental Ratings
AGIO
LGND
OUTLOOK RATING
1..100
6168
VALUATION
overvalued / fair valued / undervalued
1..100
38
Fair valued
72
Overvalued
PROFIT vs RISK RATING
1..100
10039
SMR RATING
1..100
1795
PRICE GROWTH RATING
1..100
5139
P/E GROWTH RATING
1..100
6090
SEASONALITY SCORE
1..100
9050

Tickeron ratings are formulated such that a rating of 1 designates the most successful stocks in a given industry, while a rating of 100 points to the least successful stocks for that industry.

AGIO's Valuation (38) in the Biotechnology industry is somewhat better than the same rating for LGND (72). This means that AGIO’s stock grew somewhat faster than LGND’s over the last 12 months.

LGND's Profit vs Risk Rating (39) in the Biotechnology industry is somewhat better than the same rating for AGIO (100). This means that LGND’s stock grew somewhat faster than AGIO’s over the last 12 months.

AGIO's SMR Rating (17) in the Biotechnology industry is significantly better than the same rating for LGND (95). This means that AGIO’s stock grew significantly faster than LGND’s over the last 12 months.

LGND's Price Growth Rating (39) in the Biotechnology industry is in the same range as AGIO (51). This means that LGND’s stock grew similarly to AGIO’s over the last 12 months.

AGIO's P/E Growth Rating (60) in the Biotechnology industry is in the same range as LGND (90). This means that AGIO’s stock grew similarly to LGND’s over the last 12 months.

TECHNICAL ANALYSIS
Technical Analysis
AGIOLGND
RSI
ODDS (%)
N/A
Bearish Trend 3 days ago
64%
Stochastic
ODDS (%)
Bearish Trend 3 days ago
80%
Bearish Trend 3 days ago
70%
Momentum
ODDS (%)
Bullish Trend 3 days ago
81%
Bullish Trend 3 days ago
69%
MACD
ODDS (%)
Bullish Trend 3 days ago
81%
Bearish Trend 3 days ago
72%
TrendWeek
ODDS (%)
Bullish Trend 3 days ago
80%
Bullish Trend 3 days ago
75%
TrendMonth
ODDS (%)
Bullish Trend 3 days ago
82%
Bullish Trend 3 days ago
76%
Advances
ODDS (%)
Bullish Trend 17 days ago
77%
Bullish Trend 18 days ago
75%
Declines
ODDS (%)
Bearish Trend 4 days ago
75%
Bearish Trend 4 days ago
72%
BollingerBands
ODDS (%)
Bearish Trend 3 days ago
88%
Bearish Trend 3 days ago
68%
Aroon
ODDS (%)
Bullish Trend 3 days ago
78%
Bullish Trend 3 days ago
81%
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AGIO
Daily Signalchanged days ago
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LGND
Daily Signalchanged days ago
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AGIO and

Correlation & Price change

A.I.dvisor indicates that over the last year, AGIO has been loosely correlated with LGND. These tickers have moved in lockstep 49% of the time. This A.I.-generated data suggests there is some statistical probability that if AGIO jumps, then LGND could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To AGIO
1D Price
Change %
AGIO100%
+6.34%
LGND - AGIO
49%
Loosely correlated
+1.78%
VRDN - AGIO
49%
Loosely correlated
+5.82%
CRNX - AGIO
47%
Loosely correlated
+27.92%
OCUL - AGIO
46%
Loosely correlated
+2.37%
IMVT - AGIO
46%
Loosely correlated
+3.57%
More

LGND and

Correlation & Price change

A.I.dvisor indicates that over the last year, LGND has been loosely correlated with AGIO. These tickers have moved in lockstep 49% of the time. This A.I.-generated data suggests there is some statistical probability that if LGND jumps, then AGIO could also see price increases.

1D
1W
1M
1Q
6M
1Y
5Y
Ticker /
NAME
Correlation
To LGND
1D Price
Change %
LGND100%
+1.78%
AGIO - LGND
49%
Loosely correlated
+6.34%
CRSP - LGND
47%
Loosely correlated
+2.24%
SYRE - LGND
46%
Loosely correlated
+4.04%
ACLX - LGND
45%
Loosely correlated
+1.72%
OCUL - LGND
44%
Loosely correlated
+2.37%
More