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Jul 23, 2024

$ATXS, $CBAY, $ARDX, $VKTX: Metabolic Biotech Stocks Surge 10.24% in a Week

In the past week, biotechnology companies focusing on metabolic treatments have shown a notable performance increase of +10.24%. However, a deeper analysis reveals a negative outlook for these companies, as indicated by various technical indicators and market trends. Here's a comprehensive breakdown of key elements affecting this sector.

Group Tickers: The companies within this metabolic biotech theme include Intercept Pharmaceuticals (ICPT), Astria Therapeutics (ATXS), CymaBay Therapeutics (CBAY), Ardelyx (ARDX), Viking Therapeutics (VKTX), Madrigal Pharmaceuticals (MDGL), and Rhythm Pharmaceuticals (RYTM).

Stock Outlook: Despite the recent positive performance, the 15-indicator Stock Fear & Greed Index suggests a negative outlook. Tickeron predicts a further decline of over 4.00% within the next month, with a confidence level of 72%. The daily ratio of advancing to declining volumes over the past month was 2.46 to 1, reinforcing the prevailing negative sentiment.

Market Capitalization: The average market capitalization for the group stands at 1.6 billion dollars. The range is broad, with MDGL holding the highest valuation at 3.9 billion dollars and ATXS being the least valued at 171 million dollars.

Price Movements: While the average weekly price growth was 5.21%, the monthly and quarterly averages were more substantial at 22.14% and 72.85%, respectively. Notable mentions include ARDX experiencing the highest price growth at 31.94%, while RYTM saw a decline of -3.22%.

Noteworthy Events:

  • Viking Therapeutics (VKTX): Notably, VKTX emerged as a top weekly gainer with a +9.32% jump.
  • Ardelyx (ARDX): In a previous week, ARDX also saw a significant weekly gain of +10.45%, with expectations of an uptrend continuation.
  • CymaBay Therapeutics (CBAY): CBAY, on the other hand, was a top loser for the week, declining by -7.1%.

Volume Analysis: Volume growth across the group was robust, with average weekly, monthly, and quarterly volume growth rates of 27.1%, 43.89%, and 260.1%, respectively. Notably, there were sporadic instances of substantial volume spikes, such as Astria Therapeutics experiencing a record-breaking daily growth of 531% of the 65-Day Volume Moving Average.

Individual Stock Analysis:

  1. ATXS (Astria Therapeutics):

    • Aroon Indicator: The Aroon Indicator for ATXS shows a bullish signal, indicating a potential upward move. Historical data reveals a 90% success rate in similar situations, with a recent +61% uptrend.
  2. CBAY (CymaBay Therapeutics):

    • MACD Histogram: CBAY's MACD Histogram turned negative, suggesting a bearish outlook. Historical analysis indicates an 81% likelihood of a downward move, despite a recent uptrend of +15%.
  3. ARDX (Ardelyx):

    • Aroon Indicator: ARDX's Aroon Indicator signals a likely upward move. With an 87% historical success rate, the recent +63% uptrend strengthens the potential for further positive movement.

Summary: While recent performance figures suggest positive momentum in the biotech metabolic sector, caution is warranted. The negative outlook, as indicated by the Stock Fear & Greed Index and Tickeron's predictions, coupled with sporadic volume spikes and individual stock signals, emphasizes the volatility and uncertainty in this space. Investors should closely monitor these developments and consider a diversified approach to mitigate risks in this dynamic market.

Related Ticker: ATXS, CBAY, ARDX, VKTX, MDGL, RYTM, ICPT

ATXS in -2.87% downward trend, declining for three consecutive days on January 13, 2026

Moving lower for three straight days is viewed as a bearish sign. Keep an eye on this stock for future declines. Considering data from situations where ATXS declined for three days, in of 312 cases, the price declined further within the following month. The odds of a continued downward trend are .

Price Prediction Chart

Technical Analysis (Indicators)

Bearish Trend Analysis

The Momentum Indicator moved below the 0 level on January 09, 2026. You may want to consider selling the stock, shorting the stock, or exploring put options on ATXS as a result. In of 94 cases where the Momentum Indicator fell below 0, the stock fell further within the subsequent month. The odds of a continued downward trend are .

ATXS moved below its 50-day moving average on January 16, 2026 date and that indicates a change from an upward trend to a downward trend.

Bullish Trend Analysis

The Stochastic Oscillator shows that the ticker has stayed in the oversold zone for 4 days. The price of this ticker is presumed to bounce back soon, since the longer the ticker stays in the oversold zone, the more promptly an upward trend is expected.

Following a 3-day Advance, the price is estimated to grow further. Considering data from situations where ATXS advanced for three days, in of 260 cases, the price rose further within the following month. The odds of a continued upward trend are .

ATXS may jump back above the lower band and head toward the middle band. Traders may consider buying the stock or exploring call options.

The Aroon Indicator entered an Uptrend today. In of 193 cases where ATXS Aroon's Indicator entered an Uptrend, the price rose further within the following month. The odds of a continued Uptrend are .

The Tickeron Price Growth Rating for this company is (best 1 - 100 worst), indicating steady price growth. ATXS’s price grows at a higher rate over the last 12 months as compared to S&P 500 index constituents.

The Tickeron Valuation Rating of (best 1 - 100 worst) indicates that the company is slightly overvalued in the industry. This rating compares market capitalization estimated by our proprietary formula with the current market capitalization. This rating is based on the following metrics, as compared to industry averages: P/B Ratio (5.160) is normal, around the industry mean (27.905). P/E Ratio (0.000) is within average values for comparable stocks, (51.163). Projected Growth (PEG Ratio) (0.000) is also within normal values, averaging (1.895). Dividend Yield (0.000) settles around the average of (0.056) among similar stocks. P/S Ratio (1000.000) is also within normal values, averaging (324.226).

The Tickeron Seasonality Score of (best 1 - 100 worst) indicates that the company is significantly overvalued in the industry. The Tickeron Seasonality score describes the variance of predictable price changes around the same period every calendar year. These changes can be tied to a specific month, quarter, holiday or vacation period, as well as a meteorological or growing season.

The Tickeron SMR rating for this company is (best 1 - 100 worst), indicating weak sales and an unprofitable business model. SMR (Sales, Margin, Return on Equity) rating is based on comparative analysis of weighted Sales, Income Margin and Return on Equity values compared against S&P 500 index constituents. The weighted SMR value is a proprietary formula developed by Tickeron and represents an overall profitability measure for a stock.

The Tickeron PE Growth Rating for this company is (best 1 - 100 worst), pointing to worse than average earnings growth. The PE Growth rating is based on a comparative analysis of stock PE ratio increase over the last 12 months compared against S&P 500 index constituents.

The Tickeron Profit vs. Risk Rating rating for this company is (best 1 - 100 worst), indicating that the returns do not compensate for the risks. ATXS’s unstable profits reported over time resulted in significant Drawdowns within these last five years. A stable profit reduces stock drawdown and volatility. The average Profit vs. Risk Rating rating for the industry is 94, placing this stock worse than average.

Notable companies

The most notable companies in this group are Regeneron Pharmaceuticals (NASDAQ:REGN), Incyte Corp (NASDAQ:INCY), Moderna (NASDAQ:MRNA), Exelixis (NASDAQ:EXEL), Arrowhead Pharmaceuticals (NASDAQ:ARWR), Adaptive Biotechnologies Corp (NASDAQ:ADPT), Sarepta Therapeutics (NASDAQ:SRPT), Novavax (NASDAQ:NVAX), Nektar Therapeutics (NASDAQ:NKTR), Inovio Pharmaceuticals (NASDAQ:INO).

Industry description

Biotechnology involves genetic or protein engineering to produce medicines/therapies for treating and preventing ailments. The industry also provides crucial ingredients for diagnostics. This multi-billion-dollar industry is heavily focused on research and development, as companies attempt to continually come up with cutting-edge solutions for health. New discoveries for the treatment of diseases provide opportunities for growth for a company in this industry. Discoveries, however, must pass the regulatory approval from the U.S. Food and Drug Administration (FDA) before they can make it to markets. Amgen Inc., Gilead Sciences, Inc. and Celgene Corporation are examples of companies in this industry.

Market Cap

The average market capitalization across the Biotechnology Industry is 2.25B. The market cap for tickers in the group ranges from 58 to 111.98B. VRTX holds the highest valuation in this group at 111.98B. The lowest valued company is SEELQ at 58.

High and low price notable news

The average weekly price growth across all stocks in the Biotechnology Industry was 1%. For the same Industry, the average monthly price growth was 4%, and the average quarterly price growth was 42%. LADX experienced the highest price growth at 900%, while ATRA experienced the biggest fall at -67%.

Volume

The average weekly volume growth across all stocks in the Biotechnology Industry was 27%. For the same stocks of the Industry, the average monthly volume growth was -9% and the average quarterly volume growth was 26%

Fundamental Analysis Ratings

The average fundamental analysis ratings, where 1 is best and 100 is worst, are as follows

Valuation Rating: 50
P/E Growth Rating: 81
Price Growth Rating: 57
SMR Rating: 92
Profit Risk Rating: 94
Seasonality Score: 13 (-100 ... +100)
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ATXS
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A.I.Advisor
published price charts
These past five trading days, the stock lost 0.00% with an average daily volume of 0 shares traded.The stock tracked a drawdown of 0% for this period. ATXS showed earnings on November 12, 2025. You can read more about the earnings report here.
A.I. Advisor
published General Information

General Information

a developer of new medicines for the treatment of cardiovascular, metabolic and inflammatory diseases

Industry Biotechnology

Profile
Fundamentals
Details
Industry
Biotechnology
Address
75 State Street
Phone
+1 617 349-1971
Employees
59
Web
https://www.astriatx.com
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